CA2066661C - Viral vaccine conjugates - Google Patents

Viral vaccine conjugates Download PDF

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Publication number
CA2066661C
CA2066661C CA002066661A CA2066661A CA2066661C CA 2066661 C CA2066661 C CA 2066661C CA 002066661 A CA002066661 A CA 002066661A CA 2066661 A CA2066661 A CA 2066661A CA 2066661 C CA2066661 C CA 2066661C
Authority
CA
Canada
Prior art keywords
vaccine
virus
live
pharmaceutically acceptable
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002066661A
Other languages
English (en)
French (fr)
Other versions
CA2066661A1 (en
Inventor
Craig E. Whitfill
Tommy L. Fredericksen
Julius K. Tyczkowski
James P. Thaxton, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Arkansas at Little Rock
Original Assignee
Embrex LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Embrex LLC filed Critical Embrex LLC
Priority claimed from PCT/US1990/005581 external-priority patent/WO1991004750A1/en
Publication of CA2066661A1 publication Critical patent/CA2066661A1/en
Application granted granted Critical
Publication of CA2066661C publication Critical patent/CA2066661C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Chemical Treatment Of Metals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002066661A 1989-10-02 1990-10-01 Viral vaccine conjugates Expired - Lifetime CA2066661C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US41603589A 1989-10-02 1989-10-02
US416,035 1989-10-02
US48067890A 1990-02-15 1990-02-15
US480,678 1990-02-15
US586,859 1990-09-21
US58685990A 1990-09-24 1990-09-24
PCT/US1990/005581 WO1991004750A1 (en) 1989-10-02 1990-10-01 Method of treatment

Publications (2)

Publication Number Publication Date
CA2066661A1 CA2066661A1 (en) 1991-04-03
CA2066661C true CA2066661C (en) 2001-05-08

Family

ID=27411077

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002066661A Expired - Lifetime CA2066661C (en) 1989-10-02 1990-10-01 Viral vaccine conjugates

Country Status (11)

Country Link
US (4) US5397569A (enExample)
EP (2) EP0495008B1 (enExample)
AT (2) ATE200735T1 (enExample)
AU (2) AU6714290A (enExample)
BR (1) BR9007702A (enExample)
CA (1) CA2066661C (enExample)
DE (2) DE69030383T2 (enExample)
DK (2) DK0495008T3 (enExample)
ES (2) ES2158200T3 (enExample)
IL (1) IL95867A (enExample)
WO (1) WO1991004749A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104382A0 (en) * 1992-01-17 1993-05-13 Solvay Animal Health Inc Vaccine containing acemannan as an adjuvant
JPH07206705A (ja) * 1993-11-03 1995-08-08 American Cyanamid Co 生インオボ（ｉｎ ｏｖｏ）ワクチン
US5807551A (en) * 1996-04-01 1998-09-15 Iowa State University Research Foundation, Inc. Method to provide artificial passive immunity in birds
KR100382224B1 (ko) * 1996-09-30 2003-04-26 엠브렉스, 인코포레이티드 백신 컨쥬게이트를 이용한 능동면역 생성방법
US6592869B2 (en) 1999-08-24 2003-07-15 Teva Pharmaceutical Industries, Ltd. Vaccine composition and method of using the same
EP1212045B1 (en) * 1999-08-24 2016-08-17 Abic Biological Laboratories Ltd. A vaccine composition and method of using the same
US6682754B2 (en) 1999-11-24 2004-01-27 Willmar Poultry Company, Inc. Ovo delivery of an immunogen containing implant
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
EP1161953A3 (en) * 2000-06-09 2004-02-04 Akzo Nobel N.V. IBDV strain for in OVO administration
ZA200104596B (en) * 2000-06-09 2001-12-06 Akzo Nobel Nv IBDV strain for in ovo administration.
US7029681B2 (en) 2002-03-08 2006-04-18 Schweitzer Chemical Corporation Multiple and multivalent DNA vaccines in ovo
US7037506B2 (en) 2002-03-08 2006-05-02 Schweltzer Chemical Corporation Ltd. Vaccine accelerator factor (VAF) for improvement of vaccinations in poultry
JP4504023B2 (ja) 2002-03-22 2010-07-14 ザイモジェネティクス インコーポレーティッド 抗ｉｌ−ｔｉｆ抗体および炎症において使用する方法
US6729265B2 (en) * 2002-06-27 2004-05-04 Arkion Life Sciences Llc Supplemented antibody feed to enter the circulating system of newborns
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
WO2008147847A1 (en) * 2007-05-22 2008-12-04 Baylor College Of Medicine Immune complex vaccination as a strategy to enhance immunity in the elderly and other immune compromised populations
WO2013158217A1 (en) 2012-04-20 2013-10-24 Thomas Jefferson University Engineered antibody for inhibition of fibrosis
WO2014110092A1 (en) * 2013-01-08 2014-07-17 Humabs Biomed Sa Methods of generating robust passive and active immune responses
CN103341164B (zh) * 2013-07-19 2015-06-24 天津瑞普生物技术股份有限公司 一种鸡传染性法氏囊病抗原抗体复合物、制剂及制备方法
NZ785701A (en) 2019-09-11 2025-10-31 Zoetis Services Llc Recombinant herpesvirus of turkey vectors expressing antigens of avian pathogens and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2518978A (en) * 1946-09-12 1950-08-15 American Cyanamid Co Hog cholera vaccine
DE1041214B (de) * 1957-03-11 1958-10-16 Dr Med Karl Theurer Verfahren zur Herstellung von Impfstoffen gegen Viruserkrankungen
US3846543A (en) * 1963-01-02 1974-11-05 Monsanto Co Process for the separation of virus from non-viral proteins
US3326767A (en) * 1966-03-21 1967-06-20 Abbott Lab Avian leukosis treatment with inactivated rous sarcoma virus
US3651213A (en) * 1969-05-29 1972-03-21 Monsanto Co Method for the immunization of a living animal body against viral disease
US3853467A (en) * 1973-08-15 1974-12-10 Gen Electric Method and apparatus for immunological detection of biological particles
CA1039649A (en) * 1973-08-30 1978-10-03 General Electric Company Method of forming multilayer immunologically complexed films
JPS57136528A (en) * 1981-02-09 1982-08-23 Hayashibara Biochem Lab Inc Preparation of viral vaccine
EP0073856A1 (en) * 1981-08-28 1983-03-16 Gist-Brocades N.V. Infectious-bronchitis vaccines for poultry, combined infectious-bronchitis vaccines, process for preparing such vaccines, process for preventing infectious bronchitis and infectious-bronchitis virus strain
US4458630A (en) * 1982-06-22 1984-07-10 The United States Of America As Represented By The Secretary Of Agriculture Disease control in avian species by embryonal vaccination
US4493825A (en) * 1982-10-05 1985-01-15 Iowa State University Research Foundation Purified and antigenically selective vaccines for domestic animals
US4530831A (en) * 1982-11-02 1985-07-23 Akzo N.V. Infectious Bursal Disease vaccine
US4614793A (en) * 1983-10-14 1986-09-30 Merck & Co., Inc. Hepatitis A--subunit antigen
US4743562A (en) * 1984-08-21 1988-05-10 The Board Of Trustees Of The Leland Stanford Junior University Purified human cytomegalovirus protein
US4824668A (en) * 1987-03-09 1989-04-25 Sterwin Laboratories Inc. Attenuated infectious bursal disease virus strain and vaccine therefrom
US4956452A (en) * 1987-06-14 1990-09-11 The University Of Maryland Monoclonal antibody which neutralizes multiple strains of infectious bursal disease virus
US4867975A (en) * 1988-01-27 1989-09-19 University Of Delaware Live attenuated temperature-sensitive avian infectious bronchitis virus vaccines and preparation and use thereof
US5057314A (en) * 1988-09-30 1991-10-15 Whitfill Craig E Low molecular weight antiviral factors

Also Published As

Publication number Publication date
US6136319A (en) 2000-10-24
DE69030383T2 (de) 1997-10-23
US6299874B1 (en) 2001-10-09
ATE200735T1 (de) 2001-05-15
US5871748A (en) 1999-02-16
ES2102368T3 (es) 1997-08-01
EP0495008A1 (en) 1992-07-22
WO1991004749A1 (en) 1991-04-18
EP0755684A1 (en) 1997-01-29
DK0495008T3 (da) 1997-10-13
IL95867A0 (enExample) 1991-07-18
EP0495008B1 (en) 1997-04-02
AU641958B2 (en) 1993-10-07
ATE150976T1 (de) 1997-04-15
DK0755684T3 (da) 2001-08-20
AU6755990A (en) 1991-04-28
EP0755684B1 (en) 2001-04-25
US5397569A (en) 1995-03-14
IL95867A (en) 1994-10-07
EP0495008A4 (en) 1993-05-05
DE69033728T2 (de) 2001-11-22
AU6714290A (en) 1991-04-28
DE69033728D1 (de) 2001-05-31
ES2158200T3 (es) 2001-09-01
BR9007702A (pt) 1992-08-18
CA2066661A1 (en) 1991-04-03
DE69030383D1 (de) 1997-05-07

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