CA2064373C - Derives de la piperidine - Google Patents

Derives de la piperidine Download PDF

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Publication number
CA2064373C
CA2064373C CA 2064373 CA2064373A CA2064373C CA 2064373 C CA2064373 C CA 2064373C CA 2064373 CA2064373 CA 2064373 CA 2064373 A CA2064373 A CA 2064373A CA 2064373 C CA2064373 C CA 2064373C
Authority
CA
Canada
Prior art keywords
alkyl
substituted
nhch2c
ethyl acetate
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA 2064373
Other languages
English (en)
Other versions
CA2064373A1 (fr
Inventor
Buddy Eugene Cantrell
Dennis Michael Zimmerman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of CA2064373A1 publication Critical patent/CA2064373A1/fr
Application granted granted Critical
Publication of CA2064373C publication Critical patent/CA2064373C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA 2064373 1991-03-29 1992-03-27 Derives de la piperidine Expired - Lifetime CA2064373C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66704291A 1991-03-29 1991-03-29
US677,042 1991-03-29

Publications (2)

Publication Number Publication Date
CA2064373A1 CA2064373A1 (fr) 1992-09-30
CA2064373C true CA2064373C (fr) 2005-08-23

Family

ID=24676573

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2064373 Expired - Lifetime CA2064373C (fr) 1991-03-29 1992-03-27 Derives de la piperidine

Country Status (1)

Country Link
CA (1) CA2064373C (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8685995B2 (en) 2008-03-21 2014-04-01 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2373936C2 (ru) * 2003-04-08 2009-11-27 Проджиникс Фармасьютикалз, Инк. Применение метилналтрексона для лечения синдрома раздраженного кишечника
SI2368553T1 (sl) 2003-04-08 2015-05-29 Progenics Pharmaceuticals, Inc. Farmacevtske formulacije, vsebujoče metilnatrekson
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
ES2714198T3 (es) 2005-03-07 2019-05-27 Univ Chicago Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
MX2009010550A (es) 2007-03-29 2009-12-14 Progenics Pharm Inc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
EP3064503A1 (fr) 2007-03-29 2016-09-07 Progenics Pharmaceuticals, Inc. Antagonistes des récepteurs opioïdes périphériques et leur utilisation
CA2713568C (fr) 2008-02-06 2016-09-20 Progenics Pharmaceuticals, Inc. Preparation et utilisation de (r),(r)-2,2'-bis-methylnaltrexone
CA2676881C (fr) 2008-09-30 2017-04-25 Wyeth Antagonistes de recepteurs opioides peripheriques, et leurs utilisations

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8685995B2 (en) 2008-03-21 2014-04-01 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
US9526723B2 (en) 2008-03-21 2016-12-27 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors

Also Published As

Publication number Publication date
CA2064373A1 (fr) 1992-09-30

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