CA2046324A1 - Stabilisation de solutions de proteines hydrophobes a base d'eau et vehicules de liberation prolongee - Google Patents

Stabilisation de solutions de proteines hydrophobes a base d'eau et vehicules de liberation prolongee

Info

Publication number
CA2046324A1
CA2046324A1 CA 2046324 CA2046324A CA2046324A1 CA 2046324 A1 CA2046324 A1 CA 2046324A1 CA 2046324 CA2046324 CA 2046324 CA 2046324 A CA2046324 A CA 2046324A CA 2046324 A1 CA2046324 A1 CA 2046324A1
Authority
CA
Canada
Prior art keywords
sustained release
protein
release vehicle
phase
hydrophobic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2046324
Other languages
English (en)
Inventor
Wen-Ghih Tsang
Andrew S. Magee
Ann W. Shyr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Biotech Inc
Original Assignee
Abbott Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Biotech Inc filed Critical Abbott Biotech Inc
Publication of CA2046324A1 publication Critical patent/CA2046324A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA 2046324 1989-01-26 1990-01-10 Stabilisation de solutions de proteines hydrophobes a base d'eau et vehicules de liberation prolongee Abandoned CA2046324A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30241089A 1989-01-26 1989-01-26
US302,410 1989-01-26

Publications (1)

Publication Number Publication Date
CA2046324A1 true CA2046324A1 (fr) 1990-07-27

Family

ID=23167629

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2046324 Abandoned CA2046324A1 (fr) 1989-01-26 1990-01-10 Stabilisation de solutions de proteines hydrophobes a base d'eau et vehicules de liberation prolongee

Country Status (5)

Country Link
EP (1) EP0457837A4 (fr)
JP (1) JPH04502768A (fr)
AU (1) AU5107490A (fr)
CA (1) CA2046324A1 (fr)
WO (1) WO1990008551A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827707A (en) * 1995-06-07 1998-10-27 Neocrin Company Method for manufacturing minimal volume capsules containing biological materials
US6656508B2 (en) * 1997-04-17 2003-12-02 Amgen Inc. Sustained-release alginate gels
EP0947201B1 (fr) * 1998-02-04 2006-06-28 Curis, Inc. Compositions pharmaceutiques contenant des protéines Hedgehog, et leur utilisation
EP1025861A1 (fr) * 1999-02-04 2000-08-09 Roche Diagnostics GmbH Compositions pharmaceutiques des Proteines Hedgehog rendues hydrophobes, et leur utilisation
JP4623233B2 (ja) * 2009-02-02 2011-02-02 Ｊｆｅスチール株式会社 高強度溶融亜鉛めっき鋼板およびその製造方法
CN107208025A (zh) 2014-11-25 2017-09-26 康宁股份有限公司 延续细胞培养基的材料和方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1160892A (fr) * 1980-04-04 1984-01-24 Soliman Y. K. Shenouda Fibres artificielles a base de proteines
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
WO1985005029A1 (fr) * 1984-05-09 1985-11-21 Medaphore Inc. Insuline administree par voie orale et son procede de preparation
EP0193917A3 (fr) * 1985-03-06 1987-09-23 American Cyanamid Company Compositions dispersibles et solubles dans l'eau de polymères pour administration parentérale

Also Published As

Publication number Publication date
WO1990008551A1 (fr) 1990-08-09
AU5107490A (en) 1990-08-24
EP0457837A1 (fr) 1991-11-27
JPH04502768A (ja) 1992-05-21
EP0457837A4 (en) 1993-09-15

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Legal Events

Date Code Title Description
FZDE Dead