JPH04502768A - 疎水性蛋白質水溶液の安定化及び持続的放出ビヒクル - Google Patents

疎水性蛋白質水溶液の安定化及び持続的放出ビヒクル

Info

Publication number
JPH04502768A
JPH04502768A JP50368490A JP50368490A JPH04502768A JP H04502768 A JPH04502768 A JP H04502768A JP 50368490 A JP50368490 A JP 50368490A JP 50368490 A JP50368490 A JP 50368490A JP H04502768 A JPH04502768 A JP H04502768A
Authority
JP
Japan
Prior art keywords
sustained release
protein
release vehicle
phase
hydrophobic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP50368490A
Other languages
English (en)
Japanese (ja)
Inventor
ツァン，ウェンギ
マギー，アンドルー　エス．
シル，アン　ダブリュー．
Original Assignee
アボット　バイオテク，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アボット　バイオテク，インコーポレイテッド filed Critical アボット　バイオテク，インコーポレイテッド
Publication of JPH04502768A publication Critical patent/JPH04502768A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP50368490A 1989-01-26 1990-01-10 疎水性蛋白質水溶液の安定化及び持続的放出ビヒクル Pending JPH04502768A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30241089A 1989-01-26 1989-01-26
US302,410 1989-01-26

Publications (1)

Publication Number Publication Date
JPH04502768A true JPH04502768A (ja) 1992-05-21

Family

ID=23167629

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50368490A Pending JPH04502768A (ja) 1989-01-26 1990-01-10 疎水性蛋白質水溶液の安定化及び持続的放出ビヒクル

Country Status (5)

Country Link
EP (1) EP0457837A4 (fr)
JP (1) JPH04502768A (fr)
AU (1) AU5107490A (fr)
CA (1) CA2046324A1 (fr)
WO (1) WO1990008551A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827707A (en) * 1995-06-07 1998-10-27 Neocrin Company Method for manufacturing minimal volume capsules containing biological materials
US6656508B2 (en) 1997-04-17 2003-12-02 Amgen Inc. Sustained-release alginate gels
EP0947201B1 (fr) * 1998-02-04 2006-06-28 Curis, Inc. Compositions pharmaceutiques contenant des protéines Hedgehog, et leur utilisation
EP1025861A1 (fr) * 1999-02-04 2000-08-09 Roche Diagnostics GmbH Compositions pharmaceutiques des Proteines Hedgehog rendues hydrophobes, et leur utilisation
JP4623233B2 (ja) * 2009-02-02 2011-02-02 Ｊｆｅスチール株式会社 高強度溶融亜鉛めっき鋼板およびその製造方法
PL3224341T3 (pl) 2014-11-25 2021-11-08 Corning Incorporated Materiały i sposoby do przedłużania pożywki do hodowli komórkowej

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1160892A (fr) * 1980-04-04 1984-01-24 Soliman Y. K. Shenouda Fibres artificielles a base de proteines
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
WO1985005029A1 (fr) * 1984-05-09 1985-11-21 Medaphore Inc. Insuline administree par voie orale et son procede de preparation
EP0193917A3 (fr) * 1985-03-06 1987-09-23 American Cyanamid Company Compositions dispersibles et solubles dans l'eau de polymères pour administration parentérale

Also Published As

Publication number Publication date
CA2046324A1 (fr) 1990-07-27
AU5107490A (en) 1990-08-24
EP0457837A4 (en) 1993-09-15
WO1990008551A1 (fr) 1990-08-09
EP0457837A1 (fr) 1991-11-27

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