CA2020158A1 - Procede de purification du (25,35)-2, 3-dihydro-3-hydroxy -2-(4-methoxy-phenyl)-1, 5-benzothiazepine-4(5h)-one - Google Patents

Procede de purification du (25,35)-2, 3-dihydro-3-hydroxy -2-(4-methoxy-phenyl)-1, 5-benzothiazepine-4(5h)-one

Info

Publication number
CA2020158A1
CA2020158A1 CA2020158A CA2020158A CA2020158A1 CA 2020158 A1 CA2020158 A1 CA 2020158A1 CA 2020158 A CA2020158 A CA 2020158A CA 2020158 A CA2020158 A CA 2020158A CA 2020158 A1 CA2020158 A1 CA 2020158A1
Authority
CA
Canada
Prior art keywords
benzothiazepin
dihydro
hydroxy
purification
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2020158A
Other languages
English (en)
Other versions
CA2020158C (fr
Inventor
Claudio Giordano
Dario Tentorio
Laura Russo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zach System SpA
Original Assignee
Zambon Group SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA filed Critical Zambon Group SpA
Publication of CA2020158A1 publication Critical patent/CA2020158A1/fr
Application granted granted Critical
Publication of CA2020158C publication Critical patent/CA2020158C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002020158A 1989-07-12 1990-06-29 Procede de purification du (25,35)-2, 3-dihydro-3-hydroxy -2-(4-methoxy-phenyl)-1, 5-benzothiazepine-4(5h)-one Expired - Lifetime CA2020158C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8921166A IT1234387B (it) 1989-07-12 1989-07-12 Processo di purificazione di intermedi utili nella preparazione del diltiazem
IT21166A/89 1989-07-12

Publications (2)

Publication Number Publication Date
CA2020158A1 true CA2020158A1 (fr) 1991-01-13
CA2020158C CA2020158C (fr) 1997-03-04

Family

ID=11177746

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002020158A Expired - Lifetime CA2020158C (fr) 1989-07-12 1990-06-29 Procede de purification du (25,35)-2, 3-dihydro-3-hydroxy -2-(4-methoxy-phenyl)-1, 5-benzothiazepine-4(5h)-one

Country Status (13)

Country Link
US (1) US5315005A (fr)
JP (1) JP2979240B2 (fr)
AT (1) AT401649B (fr)
BE (1) BE1003313A3 (fr)
CA (1) CA2020158C (fr)
CH (1) CH680219A5 (fr)
DE (1) DE4021999C2 (fr)
ES (1) ES2020722A6 (fr)
FR (1) FR2649706B1 (fr)
GB (1) GB2233646B (fr)
IT (1) IT1234387B (fr)
NL (1) NL9001515A (fr)
SE (1) SE509636C2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559229A (en) * 1995-06-01 1996-09-24 Acic (Canada) Inc. Method for the manufacture of benzothiazepine
US7513937B2 (en) 2005-07-08 2009-04-07 Refined Global Solutions, Inc. Oil reconditioning device and associated methods

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
FR2360124A1 (fr) * 1976-07-30 1978-02-24 Amiens Const Electro Mecan Procede de controle de commutation de la puissance de chauffage dans un appareil electrodomestique a programmateur et dispositif pour la mise en oeuvre dudit procede
DE3263466D1 (en) * 1981-02-27 1985-06-20 Tanabe Seiyaku Co Novel process for preparing threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)-propionic ester
SE449611B (sv) * 1982-07-09 1987-05-11 Tanabe Seiyaku Co Sett att framstella 1,5-bensotiazepinderivat
IT1152721B (it) * 1982-10-15 1987-01-07 Luso Farmaco Inst Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico
IT1217988B (it) * 1988-01-28 1990-03-30 Ind Chimica Profarmaco Spa Procedimento per la risoluzione ottica di un pacemo
ZA893392B (en) * 1988-05-24 1990-01-31 Hoffmann La Roche Process for the manufacture of optically active naphthothiazepinones
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
FR2642425A1 (fr) * 1989-01-30 1990-08-03 Sanofi Sa Procede de preparation de derives de benzothiazepine-1,5 one-4
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
JPH0798813B2 (ja) * 1989-04-28 1995-10-25 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体の製法
DE69015682T2 (de) * 1989-04-28 1995-05-11 Tanabe Seiyaku Co Verfahren zur Herstellung von 1,5-Benzothiazepinderivaten.

Also Published As

Publication number Publication date
NL194274B (fr) 2001-07-02
AT401649B (de) 1996-10-25
GB2233646A (en) 1991-01-16
NL9001515A (nl) 1991-02-01
DE4021999C2 (de) 2002-08-29
GB9014799D0 (en) 1990-08-22
IT1234387B (it) 1992-05-18
ES2020722A6 (es) 1991-09-01
NL194274C (fr) 2001-11-05
SE9002410L (sv) 1991-01-13
FR2649706A1 (fr) 1991-01-18
ATA147690A (de) 1996-03-15
US5315005A (en) 1994-05-24
JP2979240B2 (ja) 1999-11-15
IT8921166A0 (it) 1989-07-12
SE9002410D0 (sv) 1990-07-11
GB2233646B (en) 1993-01-27
CA2020158C (fr) 1997-03-04
CH680219A5 (fr) 1992-07-15
JPH0348671A (ja) 1991-03-01
DE4021999A1 (de) 1991-01-17
SE509636C2 (sv) 1999-02-15
BE1003313A3 (fr) 1992-02-25
FR2649706B1 (fr) 1994-10-07

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