CA2013225A1 - Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs - Google Patents

Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs

Info

Publication number
CA2013225A1
CA2013225A1 CA002013225A CA2013225A CA2013225A1 CA 2013225 A1 CA2013225 A1 CA 2013225A1 CA 002013225 A CA002013225 A CA 002013225A CA 2013225 A CA2013225 A CA 2013225A CA 2013225 A1 CA2013225 A1 CA 2013225A1
Authority
CA
Canada
Prior art keywords
composition
monoacyl
phosphoglyceride
lysolecithin
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002013225A
Other languages
English (en)
French (fr)
Inventor
Tai-Lee Ke
Jamieson C. Keister
Eugene R. Cooper
Douglas F. Hager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2013225A1 publication Critical patent/CA2013225A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA002013225A 1989-03-29 1990-03-28 Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs Abandoned CA2013225A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32992489A 1989-03-29 1989-03-29
US329,924 1989-03-29

Publications (1)

Publication Number Publication Date
CA2013225A1 true CA2013225A1 (en) 1990-09-29

Family

ID=23287604

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002013225A Abandoned CA2013225A1 (en) 1989-03-29 1990-03-28 Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs

Country Status (7)

Country Link
EP (1) EP0465580A4 (xx)
JP (1) JPH04504258A (xx)
AU (1) AU631204B2 (xx)
CA (1) CA2013225A1 (xx)
IL (1) IL93925A0 (xx)
WO (1) WO1990011079A1 (xx)
ZA (1) ZA902442B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109118A (en) * 1989-07-06 1992-04-28 Yutaka Mizushima Modified biologically active proteins
FR2673513B1 (fr) * 1991-03-05 1993-10-29 Institut Recherche Biologique Sa Nouvelles compositions dietetiques a base de lipides phosphoryles et leur utilisation dans l'amelioration des troubles de la vision.
PT1019417E (pt) 1997-08-18 2003-03-31 Max Planck Ges Zur Forderung W Compostos analogos de fosfolipidos
PL2574341T3 (pl) 2004-03-29 2017-09-29 University Of South Florida Efektywne leczenie guzów i raka fosforanem tricyrybiny
US8669241B2 (en) * 2008-12-02 2014-03-11 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
WO2019193513A1 (en) * 2018-04-03 2019-10-10 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62270521A (ja) * 1986-05-16 1987-11-24 Green Cross Corp:The フルルビプロフエン眼投与製剤
GB8712176D0 (en) * 1987-05-22 1987-06-24 Cosmas Damian Ltd Drug delivery system

Also Published As

Publication number Publication date
AU631204B2 (en) 1992-11-19
ZA902442B (en) 1991-01-30
JPH04504258A (ja) 1992-07-30
IL93925A0 (en) 1990-12-23
EP0465580A1 (en) 1992-01-15
AU5403090A (en) 1990-10-22
EP0465580A4 (en) 1992-03-18
WO1990011079A1 (en) 1990-10-04

Similar Documents

Publication Publication Date Title
US8008255B2 (en) Methods and compositions for enhanced transmucosal delivery of peptides and proteins
US10829518B2 (en) Peptide compositions and methods of use
RU2572214C2 (ru) Способ получения цинковых комплексов инсулина
EP1720520B1 (en) Particles comprising a core of calcium phosphate nanoparticles, a biomolecule and a bile acid, methods of manufacturing, therapeutic use thereof
AU2010277560B2 (en) Long acting insulin composition
US20150157725A1 (en) Transmucosal delivery of peptides and proteins
KR20140103099A (ko) 안구 병태의 예방 및 치료
AU2010277559A1 (en) Prodrugs comprising an insulin linker conjugate
EP1093818A1 (en) Powdery preparation for mucosal administration containing polymeric medicine
CA2013225A1 (en) Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs
US20130004592A1 (en) Pharmaceutical compositions for parenteral administration
US11298399B2 (en) Carbetocin drug product and process for preparing same
ES2221530A1 (es) Nanoparticulas para la administracion de ingredientes activos,procedimiento para la elaboracion de dichas particulas y composicion que las contiene.
Melgar-Asensio et al. Extended intravitreal rabbit eye residence of nanoparticles conjugated with cationic arginine peptides for intraocular drug delivery: in vivo imaging
CN116036292A (zh) 一种具有增溶和促吸收作用的低共熔混合物及载药组合物
WO2023045778A1 (zh) 一种自分散粒子系统及其制备与应用
WO2023221774A1 (zh) 一种姜黄自分散粒子系统及其制备方法、制备装置与应用
ES2944784A1 (es) Microemulsión oftálmica, procedimiento de obtención y uso dado a la misma
WO2023166528A1 (en) "formulation for nasal delivery of insulin and other proteins and peptides"
CN118717705A (zh) 一种新型核黄素-脂质纳米颗粒复合制剂及其应用
US20160271060A1 (en) Ophthalmic emulsion composition of cyclosporine

Legal Events

Date Code Title Description
FZDE Discontinued