EP0465580A4 - Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs - Google Patents

Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs

Info

Publication number
EP0465580A4
EP0465580A4 EP19900906019 EP90906019A EP0465580A4 EP 0465580 A4 EP0465580 A4 EP 0465580A4 EP 19900906019 EP19900906019 EP 19900906019 EP 90906019 A EP90906019 A EP 90906019A EP 0465580 A4 EP0465580 A4 EP 0465580A4
Authority
EP
European Patent Office
Prior art keywords
enhance
ophthalmic drugs
corneal penetration
phosphoglycerides
monoacyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900906019
Other versions
EP0465580A1 (en
Inventor
Tai-Lee Ke
Eugene R. Cooper
Douglas F. Hager
Jamieson Charles Keister
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of EP0465580A1 publication Critical patent/EP0465580A1/en
Publication of EP0465580A4 publication Critical patent/EP0465580A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP19900906019 1989-03-29 1990-03-28 Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs Withdrawn EP0465580A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US329924 1988-03-29
US32992489A 1989-03-29 1989-03-29

Publications (2)

Publication Number Publication Date
EP0465580A1 EP0465580A1 (en) 1992-01-15
EP0465580A4 true EP0465580A4 (en) 1992-03-18

Family

ID=23287604

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900906019 Withdrawn EP0465580A4 (en) 1989-03-29 1990-03-28 Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs

Country Status (7)

Country Link
EP (1) EP0465580A4 (en)
JP (1) JPH04504258A (en)
AU (1) AU631204B2 (en)
CA (1) CA2013225A1 (en)
IL (1) IL93925A0 (en)
WO (1) WO1990011079A1 (en)
ZA (1) ZA902442B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109118A (en) * 1989-07-06 1992-04-28 Yutaka Mizushima Modified biologically active proteins
FR2673513B1 (en) * 1991-03-05 1993-10-29 Institut Recherche Biologique Sa NOVEL DIETETIC COMPOSITIONS BASED ON PHOSPHORYLATED LIPIDS AND THEIR USE IN IMPROVING VISION DISORDERS.
US6344576B1 (en) 1997-08-18 2002-02-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Phospholipid-analogous compounds
PL2574341T3 (en) 2004-03-29 2017-09-29 University Of South Florida Effective treatment of tumors and cancer with triciribine phosphate
US8669241B2 (en) * 2008-12-02 2014-03-11 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
US20210038612A1 (en) * 2018-04-03 2021-02-11 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253472A1 (en) * 1986-05-16 1988-01-20 Green Cross Corporation Ophthalmic flurbiprofen preparation
WO1988009163A1 (en) * 1987-05-22 1988-12-01 Danbiosyst U.K. Limited Enhanced uptake drug delivery system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253472A1 (en) * 1986-05-16 1988-01-20 Green Cross Corporation Ophthalmic flurbiprofen preparation
WO1988009163A1 (en) * 1987-05-22 1988-12-01 Danbiosyst U.K. Limited Enhanced uptake drug delivery system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9011079A1 *

Also Published As

Publication number Publication date
CA2013225A1 (en) 1990-09-29
EP0465580A1 (en) 1992-01-15
AU631204B2 (en) 1992-11-19
WO1990011079A1 (en) 1990-10-04
AU5403090A (en) 1990-10-22
IL93925A0 (en) 1990-12-23
JPH04504258A (en) 1992-07-30
ZA902442B (en) 1991-01-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19910927

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HAGER, DOUGLAS, F.

Inventor name: COOPER, EUGENE, R.

Inventor name: KE, TAI-LEE

Inventor name: KEISTER, JAMIESON, CHARLES

A4 Supplementary search report drawn up and despatched

Effective date: 19920127

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE

17Q First examination report despatched

Effective date: 19930202

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930615