CA2008911A1 - Process for preparing ethyl 6-bromo-5-hydroxy-4- dimethylaminomethyl-1-methyl-2-phenylthiomethylindole-3- carboxylate hydrochloride monohydrate and a pharmaceutical preparation containing the same having the antiviral, interferon-inducing and immunomodulatory effects - Google Patents

Process for preparing ethyl 6-bromo-5-hydroxy-4- dimethylaminomethyl-1-methyl-2-phenylthiomethylindole-3- carboxylate hydrochloride monohydrate and a pharmaceutical preparation containing the same having the antiviral, interferon-inducing and immunomodulatory effects

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Publication number
CA2008911A1
CA2008911A1 CA2008911A CA2008911A CA2008911A1 CA 2008911 A1 CA2008911 A1 CA 2008911A1 CA 2008911 A CA2008911 A CA 2008911A CA 2008911 A CA2008911 A CA 2008911A CA 2008911 A1 CA2008911 A1 CA 2008911A1
Authority
CA
Canada
Prior art keywords
bromo
hydroxy
ethyl
dimethylaminomethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2008911A
Other languages
French (fr)
Other versions
CA2008911C (en
Inventor
Fedor A. Trofimov
Nina G. Tsyshkova
Nadezhda S. Bogdanova
Irina S. Nikolaeva
Svetlana A. Zotova
Ljudmila A. Savinova
Alexei Nikolaevich Grinev
Grigory Nikolaevich Pershin
Zinaida M. Sakhaschik
Evgenia A. Svirina
Alla N. Fomina
Elena N. Padeiskaya
Dmitry M. Zlydnikov
Olga I. Kubar
Evgenia G. Shvetsova
Elena A. Bryantseva
Valentina V. Peters
Svetlana N. Kutchak
Anatoly G. Konoplyannikov
Boris P. Surinov
Vera A. Yadrovskaya
Elena P. Savina
Nina A. Karpova
Ljudmila S. Safonova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LENINGRADSKY NAUCHNO-ISSLEDOVATELSKY INSTITUT EPIDEMIOLOGII I MIKROBIOLOGII IMENI PASTERA
NAUCHNO-ISSLEDOVATELSKY INSTITUT MEDITSINSKOI RADIOLOGII AKADEMII MEDITSINSKIKH NAUK SSSR
Vsesojuzny Nauchno-Issledovatelsky Khimiko-Farmatsevtichesky Institut Imeni Sordzhonikidze (vnikhfi)
Original Assignee
LENINGRADSKY NAUCHNO-ISSLEDOVATELSKY INSTITUT EPIDEMIOLOGII I MIKROBIOLOGII IMENI PASTERA
NAUCHNO-ISSLEDOVATELSKY INSTITUT MEDITSINSKOI RADIOLOGII AKADEMII MEDITSINSKIKH NAUK SSSR
Vsesojuzny Nauchno-Issledovatelsky Khimiko-Farmatsevtichesky Institut Imeni Sordzhonikidze (vnikhfi)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LENINGRADSKY NAUCHNO-ISSLEDOVATELSKY INSTITUT EPIDEMIOLOGII I MIKROBIOLOGII IMENI PASTERA, NAUCHNO-ISSLEDOVATELSKY INSTITUT MEDITSINSKOI RADIOLOGII AKADEMII MEDITSINSKIKH NAUK SSSR, Vsesojuzny Nauchno-Issledovatelsky Khimiko-Farmatsevtichesky Institut Imeni Sordzhonikidze (vnikhfi) filed Critical LENINGRADSKY NAUCHNO-ISSLEDOVATELSKY INSTITUT EPIDEMIOLOGII I MIKROBIOLOGII IMENI PASTERA
Priority to CA002008911A priority Critical patent/CA2008911C/en
Publication of CA2008911A1 publication Critical patent/CA2008911A1/en
Application granted granted Critical
Publication of CA2008911C publication Critical patent/CA2008911C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04B—GENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
    • E04B1/00—Constructions in general; Structures which are not restricted either to walls, e.g. partitions, or floors or ceilings or roofs
    • E04B1/32—Arched structures; Vaulted structures; Folded structures
    • E04B1/3211—Structures with a vertical rotation axis or the like, e.g. semi-spherical structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04B—GENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
    • E04B1/00—Constructions in general; Structures which are not restricted either to walls, e.g. partitions, or floors or ceilings or roofs
    • E04B1/32—Arched structures; Vaulted structures; Folded structures
    • E04B2001/327—Arched structures; Vaulted structures; Folded structures comprised of a number of panels or blocs connected together forming a self-supporting structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Architecture (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Electromagnetism (AREA)
  • Civil Engineering (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A process for preparing a novel compound - ethyl 6-bromo-5-hydroxy-4-dimethylaminomethyl-1-methyl-2-phenyl-thiomethyl-3-carboxylate hydrochloride monohydrate of the following formula:
CA002008911A 1990-01-30 1990-01-30 Process for preparing ethyl 6-bromo-5-hydroxy-4- dimethylaminomethyl-1-methyl-2-phenylthiomethylindole-3- carboxylate hydrochloride monohydrate and a pharmaceutical preparation containing the same having the antiviral, interferon-inducing and immunomodulatory effects Expired - Fee Related CA2008911C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002008911A CA2008911C (en) 1990-01-30 1990-01-30 Process for preparing ethyl 6-bromo-5-hydroxy-4- dimethylaminomethyl-1-methyl-2-phenylthiomethylindole-3- carboxylate hydrochloride monohydrate and a pharmaceutical preparation containing the same having the antiviral, interferon-inducing and immunomodulatory effects

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002008911A CA2008911C (en) 1990-01-30 1990-01-30 Process for preparing ethyl 6-bromo-5-hydroxy-4- dimethylaminomethyl-1-methyl-2-phenylthiomethylindole-3- carboxylate hydrochloride monohydrate and a pharmaceutical preparation containing the same having the antiviral, interferon-inducing and immunomodulatory effects

Publications (2)

Publication Number Publication Date
CA2008911A1 true CA2008911A1 (en) 1991-07-30
CA2008911C CA2008911C (en) 1996-12-10

Family

ID=76956514

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002008911A Expired - Fee Related CA2008911C (en) 1990-01-30 1990-01-30 Process for preparing ethyl 6-bromo-5-hydroxy-4- dimethylaminomethyl-1-methyl-2-phenylthiomethylindole-3- carboxylate hydrochloride monohydrate and a pharmaceutical preparation containing the same having the antiviral, interferon-inducing and immunomodulatory effects

Country Status (1)

Country Link
CA (1) CA2008911C (en)

Also Published As

Publication number Publication date
CA2008911C (en) 1996-12-10

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