CA1327571C - Imidazodiazepine derivatives - Google Patents

Imidazodiazepine derivatives

Info

Publication number
CA1327571C
CA1327571C CA000559547A CA559547A CA1327571C CA 1327571 C CA1327571 C CA 1327571C CA 000559547 A CA000559547 A CA 000559547A CA 559547 A CA559547 A CA 559547A CA 1327571 C CA1327571 C CA 1327571C
Authority
CA
Canada
Prior art keywords
signifies
methyl
dihydro
cycloalkyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000559547A
Other languages
English (en)
French (fr)
Inventor
Walter Hunkeler
Marc Meier
Emilio Kyburz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1327571C publication Critical patent/CA1327571C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000559547A 1987-03-10 1988-02-23 Imidazodiazepine derivatives Expired - Fee Related CA1327571C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH880/87 1987-03-10
CH88087 1987-03-10
CH59/88 1988-01-08
CH5988 1988-01-08

Publications (1)

Publication Number Publication Date
CA1327571C true CA1327571C (en) 1994-03-08

Family

ID=25683391

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000559547A Expired - Fee Related CA1327571C (en) 1987-03-10 1988-02-23 Imidazodiazepine derivatives

Country Status (17)

Country Link
US (1) US4863920A (cg-RX-API-DMAC7.html)
EP (1) EP0285837B1 (cg-RX-API-DMAC7.html)
KR (1) KR880011159A (cg-RX-API-DMAC7.html)
AU (1) AU604300B2 (cg-RX-API-DMAC7.html)
CA (1) CA1327571C (cg-RX-API-DMAC7.html)
DE (1) DE3872559D1 (cg-RX-API-DMAC7.html)
DK (1) DK127288A (cg-RX-API-DMAC7.html)
ES (1) ES2051781T3 (cg-RX-API-DMAC7.html)
FI (1) FI880814A7 (cg-RX-API-DMAC7.html)
GR (1) GR3005909T3 (cg-RX-API-DMAC7.html)
HU (1) HU201763B (cg-RX-API-DMAC7.html)
IL (1) IL85624A0 (cg-RX-API-DMAC7.html)
MC (1) MC1918A1 (cg-RX-API-DMAC7.html)
NO (1) NO167027C (cg-RX-API-DMAC7.html)
NZ (1) NZ223736A (cg-RX-API-DMAC7.html)
PT (1) PT86925B (cg-RX-API-DMAC7.html)
YU (1) YU47988A (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1327572C (en) * 1988-08-31 1994-03-08 F. Hoffmann-La Roche Ag Imidazodiazepine derivatives
GB8909700D0 (en) * 1989-04-27 1989-06-14 Roussel Lab Ltd Chemical compounds
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
CA2150805C (en) * 1992-12-04 2006-08-15 Frans Eduard Janssens Antiallergic imidazo[1,2-a](pyrrolo, thieno or furano)[2,3-d]azepine derivatives
EP1781300A1 (en) 2004-07-16 2007-05-09 ProteoSys AG Muscarinic antagonists with parp and sir modulatng activity as agents for inflammatory diseases
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment
CA3004680A1 (en) * 2015-11-13 2017-05-18 Mavalon Therapeutics Limited Substituted tricyclic 1,4-benzodiazepinone derivatives as allosteric modulators of group ii metabotropic glutamate receptors
CN110769830A (zh) 2017-05-12 2020-02-07 马瓦隆治疗有限公司 作为ii组代谢型谷氨酸受体的别构调节剂的取代的杂环化合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA755418B (en) * 1974-09-11 1977-06-29 Hoffmann La Roche Diazepine derivatives
US4280957A (en) * 1974-09-11 1981-07-28 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
CA1174673A (en) * 1981-02-27 1984-09-18 Walter Hunkeler Imidazodiazepines
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
CS249146B2 (en) * 1984-01-19 1987-03-12 Hoffmann La Roche Method of new imidazodiazepine's derivatives production
DE202441T1 (de) * 1985-05-17 1987-03-19 Aktieselskabet Ferrosan, Soeborg Oxadiazolylimidazobenzodiazepine, verfahren zu ihrer herstellung und pharmazeutische zubereitungen.
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
GB8720414D0 (en) * 1987-08-28 1987-10-07 Roussel Lab Ltd Chemical compounds
CA1327572C (en) * 1988-08-31 1994-03-08 F. Hoffmann-La Roche Ag Imidazodiazepine derivatives

Also Published As

Publication number Publication date
KR880011159A (ko) 1988-10-26
IL85624A0 (en) 1988-08-31
AU1271088A (en) 1988-09-15
NO167027B (no) 1991-06-17
MC1918A1 (fr) 1989-04-06
PT86925B (pt) 1992-05-29
AU604300B2 (en) 1990-12-13
PT86925A (pt) 1988-04-01
NO881054L (no) 1988-09-12
FI880814A7 (fi) 1988-09-11
HUT47282A (en) 1989-02-28
HU201763B (en) 1990-12-28
NZ223736A (en) 1992-01-29
ES2051781T3 (es) 1994-07-01
EP0285837B1 (de) 1992-07-08
YU47988A (en) 1991-04-30
DK127288D0 (da) 1988-03-09
NO167027C (no) 1991-09-25
DE3872559D1 (de) 1992-08-13
DK127288A (da) 1988-09-11
FI880814A0 (fi) 1988-02-22
US4863920A (en) 1989-09-05
EP0285837A1 (de) 1988-10-12
NO881054D0 (no) 1988-03-09
GR3005909T3 (cg-RX-API-DMAC7.html) 1993-06-07

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