CA1318456C - Peptides - Google Patents

Peptides

Info

Publication number
CA1318456C
CA1318456C CA000551991A CA551991A CA1318456C CA 1318456 C CA1318456 C CA 1318456C CA 000551991 A CA000551991 A CA 000551991A CA 551991 A CA551991 A CA 551991A CA 1318456 C CA1318456 C CA 1318456C
Authority
CA
Canada
Prior art keywords
lys
leu
glu
val
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000551991A
Other languages
English (en)
French (fr)
Inventor
Olga Nyeki Nee Kuprina
Istvan Schon
Lajos Kisfaludy
Laszlo Denes
Gyorgy Hajos
Laszlo Szporny
Bela Szende
Karoly Lapis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of CA1318456C publication Critical patent/CA1318456C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA000551991A 1986-11-21 1987-11-17 Peptides Expired - Fee Related CA1318456C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU4827/86 1986-11-21
HU864827A HUT46044A (en) 1986-11-21 1986-11-21 Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same

Publications (1)

Publication Number Publication Date
CA1318456C true CA1318456C (en) 1993-05-25

Family

ID=10968962

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000551991A Expired - Fee Related CA1318456C (en) 1986-11-21 1987-11-17 Peptides

Country Status (12)

Country Link
US (1) US5041535A (en, 2012)
EP (1) EP0269389B1 (en, 2012)
JP (1) JPH0796557B2 (en, 2012)
AT (1) ATE81134T1 (en, 2012)
AU (1) AU597749B2 (en, 2012)
CA (1) CA1318456C (en, 2012)
DE (1) DE3782006T2 (en, 2012)
DK (1) DK610287A (en, 2012)
ES (1) ES2055708T3 (en, 2012)
GR (1) GR3006357T3 (en, 2012)
HU (1) HUT46044A (en, 2012)
IL (1) IL84551A (en, 2012)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1216908B (it) * 1987-03-19 1990-03-14 Eniricerche Spa Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.
DE69124274T2 (de) * 1990-02-27 1997-08-14 Agency Ind Science Techn Oligopeptide, sie enthaltende pharmazeutische und Futterzusammensetzung und Benützung von Oligopeptiden
US6066622A (en) * 1991-10-28 2000-05-23 Cytran, Inc. Immunomodulating peptides and methods of use
WO1995003067A1 (en) * 1993-07-21 1995-02-02 Khavinson Vladimir Khatskelevi Pharmaceutical with immunomodulating activity
CA2665351A1 (en) * 2006-10-04 2008-04-10 Inimex Pharmaceuticals Inc. Novel peptides for treating and preventing immune-related disorders, including treating and preventing infection by modulating innate immunity
RU2656188C1 (ru) * 2017-05-03 2018-06-04 Общество с ограниченной ответственностью "Анкрим" (ООО "Анкрим") Синтетическое анальгетическое средство пептидной природы и способ его применения
CN118638025A (zh) 2017-08-21 2024-09-13 细胞基因公司 制备(s)-4,5-二氨基-5-氧代戊酸叔丁酯的工艺
HUP2300355A1 (hu) * 2023-10-19 2025-04-28 Denes Laszlo Dr TP3 (thymopentin-analog) tartalmú gyógyszerkészítmény alkalmazása emlõs élõlények immunrendszerének védekezési mechanizmusában résztvevõ sejtaktivitásoknak és számának növelésével, a betegségek megelõzésére és/vagy kezelésére az átlagéletkor meghosszabbítására

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821188A (en) * 1972-06-14 1974-06-28 American Home Prod Proline and pyroglutamic acid containing tripeptides
GR73585B (en, 2012) * 1978-09-11 1984-03-26 Univ Miami
DE3161915D1 (en) * 1980-03-05 1984-02-23 Univ Miami Angiotensin converting enzyme inhibitors
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
US4629723A (en) * 1984-06-27 1986-12-16 Ortho Pharmaceutical Corporation Potent thymopentin analogs
IT1188645B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante

Also Published As

Publication number Publication date
ES2055708T3 (es) 1994-09-01
IL84551A0 (en) 1988-04-29
ATE81134T1 (de) 1992-10-15
JPH0796557B2 (ja) 1995-10-18
AU8144687A (en) 1988-05-26
US5041535A (en) 1991-08-20
DK610287A (da) 1988-05-22
AU597749B2 (en) 1990-06-07
DE3782006T2 (de) 1993-04-22
GR3006357T3 (en, 2012) 1993-06-21
HUT46044A (en) 1988-09-28
DK610287D0 (da) 1987-11-20
EP0269389A2 (en) 1988-06-01
IL84551A (en) 1992-06-21
DE3782006D1 (en) 1992-11-05
EP0269389A3 (en) 1990-02-07
JPS63198698A (ja) 1988-08-17
EP0269389B1 (en) 1992-09-30

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