CA1316786C - Systeme d'administration de medicament par ionophorese - Google Patents

Systeme d'administration de medicament par ionophorese

Info

Publication number
CA1316786C
CA1316786C CA000566715A CA566715A CA1316786C CA 1316786 C CA1316786 C CA 1316786C CA 000566715 A CA000566715 A CA 000566715A CA 566715 A CA566715 A CA 566715A CA 1316786 C CA1316786 C CA 1316786C
Authority
CA
Canada
Prior art keywords
medication
current
accordance
delivery system
body location
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000566715A
Other languages
English (en)
Inventor
Martin H. Newman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avitar Inc
Original Assignee
Martin H. Newman
Avitar, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martin H. Newman, Avitar, Inc. filed Critical Martin H. Newman
Application granted granted Critical
Publication of CA1316786C publication Critical patent/CA1316786C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
CA000566715A 1987-05-15 1988-05-13 Systeme d'administration de medicament par ionophorese Expired - Fee Related CA1316786C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5107987A 1987-05-15 1987-05-15
US051,079 1987-05-15

Publications (1)

Publication Number Publication Date
CA1316786C true CA1316786C (fr) 1993-04-27

Family

ID=21969198

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000566715A Expired - Fee Related CA1316786C (fr) 1987-05-15 1988-05-13 Systeme d'administration de medicament par ionophorese

Country Status (4)

Country Link
EP (1) EP0313638A4 (fr)
JP (1) JPH02500339A (fr)
CA (1) CA1316786C (fr)
WO (1) WO1988008729A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135477A (en) * 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US5108363A (en) * 1988-02-19 1992-04-28 Gensia Pharmaceuticals, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
IL86076A (en) * 1988-04-14 1992-12-01 Inventor S Funding Corp Ltd Transdermal drug delivery device
ES2012944A6 (es) * 1989-01-09 1990-04-16 Tomas Justribo Jose Ramon Procedimiento y su dispositivo para la admionistracion de farmacos mediante ionoforesis, para tratamiento loco-regionales.
IT1244030B (it) * 1989-12-21 1994-06-28 Elan Corp Plc Dispostitivo in due parti per la somministrazione controllata di un ingrediente
CH684725B5 (fr) * 1989-12-26 1995-06-15 Elan Corp Plc Dispositif formé de deux unités pour l'administration sélective d'un médicament.
DE4028125A1 (de) * 1990-01-17 1991-07-18 Klimke Markus Applikationsvorrichtung fuer die geregelte dosierung verschiedener pharmakons mittels elektrischem strom zum perkutanen transport zur lokalen und systemischen therapie
AU7242091A (en) * 1990-01-26 1991-08-21 Gensia Pharmaceuticals, Inc. Iontophoretic transfer electrode and method
US6004309A (en) * 1990-03-30 1999-12-21 Alza Corporation Method and apparatus for controlled environment electrotransport
AU647103B2 (en) * 1990-03-30 1994-03-17 Alza Corporation Iontophoretic delivery device
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
WO1991015261A1 (fr) * 1990-03-30 1991-10-17 Medtronic, Inc. Dispositif d'administration de medicaments par electrotransport regulee par l'activite
US5207752A (en) * 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
US5213568A (en) * 1990-03-30 1993-05-25 Medtronic Inc. Activity controlled electrotransport drug delivery device
AU7574091A (en) * 1990-04-04 1991-10-30 Isabella Koster Exciting current device for very low currents and electrodes with sensor switching
US5383848A (en) * 1990-04-12 1995-01-24 Gensia, Inc. Iontophoretic administration of drugs
US5169384A (en) * 1991-08-16 1992-12-08 Bosniak Stephen L Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue
EP0615461B1 (fr) * 1991-12-03 1996-09-25 Alza Corporation Dispositif d'administration iontophoretique et son alimentation
US5499967A (en) * 1992-02-27 1996-03-19 Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De Dietetique (L.H.D.) Transdermal drug delivery device with waveshape generator
FR2688106B1 (fr) * 1992-02-27 1994-09-09 Lhd Lab Hygiene Dietetique Dispositif de generation d'une tension electrique de forme d'onde predeterminee, appareil ionophoretique d'administration transdermique de medicaments.
DE69530290T2 (de) * 1995-01-27 2004-01-29 Alessandro Aloisi Vorrichtung für iontophoretische physiotherapie mit gefrorenen arzneikristallen
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
US6175763B1 (en) * 1996-03-29 2001-01-16 Alza Corporation Electrotransport drug delivery device having tactile signaling means
US6718201B1 (en) 1996-06-07 2004-04-06 Alza Corporation Electrotransport agent delivery method and apparatus
US6029083A (en) * 1997-04-04 2000-02-22 Becton, Dickinson And Company Circuit and method for automatically turning off an iontophoresis system
US6208891B1 (en) * 1997-04-04 2001-03-27 Drug Delivery Technologies, Inc. Disabling circuit for an iontophoretic system
FR2766093B1 (fr) * 1997-07-15 1999-09-03 Lhd Lab Hygiene Dietetique Procede de commande d'un dispositif d'administration transdermique de medicament sous champ electrique
DE69837163T2 (de) 1997-12-17 2007-11-22 Alza Corp., Mountain View Iontophoretische vorrichtung mit programmierbarer elektrischer stromeinstellung
IT1307852B1 (it) 1999-03-22 2001-11-19 Africa Antonino D Un dispositivo per la somministrazione per via transcutanea dimolecole contenute in un prodotto veicolante relativamente viscoso,
US6385488B1 (en) * 1999-05-20 2002-05-07 Vyteris, Inc. Circuits for increasing the reliability of an iontophoretic system
IT1315207B1 (it) 1999-06-09 2003-02-03 Antonino D Africa Dispositvo e metodo per il trasporto molecolare transdermico.
IT1316594B1 (it) 2000-08-02 2003-04-24 Elisabetta Rossi Elettrodo e contenitore per la somministrazione per via transcutaneadi molecole contenute in un prodotto veicolante
GB2372705A (en) * 2000-11-03 2002-09-04 Kieron Loy A hand-held self-administered iontophoretic drug applicator with roller-ball skin electrode
US6823202B2 (en) 2002-04-01 2004-11-23 Iomed, Inc. Iontophoretic power supply

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3163166A (en) * 1961-04-28 1964-12-29 Colgate Palmolive Co Iontophoresis apparatus
FR2260359A1 (en) * 1974-02-08 1975-09-05 Legrand Jean Jacques Medicament administering device - carries medicament through the skin by ionisation or electrophoresis
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4292968A (en) * 1979-11-26 1981-10-06 Sybron Corporation Electric supply for ion therapy
FR2500689A3 (fr) * 1981-02-20 1982-08-27 Faiveley Sa Generateur de courant unidirectionnel pour l'electrologie
US4416274A (en) * 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
DE3273269D1 (en) * 1981-03-06 1986-10-23 Medtronic Inc Iontophoretic electrode
EP0092015A1 (fr) * 1982-04-16 1983-10-26 Roland Brodard Dispositif d'ionisation
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
JPS6131169A (ja) * 1984-07-23 1986-02-13 株式会社アドバンス イオントフォレ−ゼ用デバイス
US4570637A (en) * 1983-10-20 1986-02-18 Andover Medical Incorporated Electrode
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
EP0225872B1 (fr) * 1985-06-10 1992-09-02 Drug Delivery Systems Inc. Commande programmable et systeme de montage d'un applicateur de medicaments transdermiques
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system

Also Published As

Publication number Publication date
EP0313638A4 (fr) 1989-06-14
WO1988008729A1 (fr) 1988-11-17
JPH02500339A (ja) 1990-02-08
EP0313638A1 (fr) 1989-05-03

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Legal Events

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