CA1315482C - Process for reducing methionine sulfoxide residues - Google Patents
Process for reducing methionine sulfoxide residuesInfo
- Publication number
- CA1315482C CA1315482C CA000574821A CA574821A CA1315482C CA 1315482 C CA1315482 C CA 1315482C CA 000574821 A CA000574821 A CA 000574821A CA 574821 A CA574821 A CA 574821A CA 1315482 C CA1315482 C CA 1315482C
- Authority
- CA
- Canada
- Prior art keywords
- peptide
- acid
- sulfide
- residues
- haloacid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
- C07K1/122—Hydrolysis with acids different from HF
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/088,739 US4835254A (en) | 1987-08-24 | 1987-08-24 | Process for reducing methionine sulfoxide residues in peptides or proteins |
| US07/088,739 | 1987-08-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1315482C true CA1315482C (en) | 1993-03-30 |
Family
ID=22213162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000574821A Expired - Fee Related CA1315482C (en) | 1987-08-24 | 1988-08-16 | Process for reducing methionine sulfoxide residues |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4835254A (ref) |
| JP (1) | JPH02262590A (ref) |
| KR (1) | KR890003798A (ref) |
| CN (1) | CN1029976C (ref) |
| BE (1) | BE1004198A3 (ref) |
| CA (1) | CA1315482C (ref) |
| CH (1) | CH675879A5 (ref) |
| DE (1) | DE3828287A1 (ref) |
| DK (1) | DK465588A (ref) |
| FR (1) | FR2619820B1 (ref) |
| GB (1) | GB2209033B (ref) |
| HU (1) | HU200438B (ref) |
| IL (1) | IL87479A (ref) |
| IT (1) | IT1226864B (ref) |
| NL (1) | NL8802041A (ref) |
| SE (1) | SE503255C2 (ref) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2682061B2 (ja) * | 1988-10-07 | 1997-11-26 | 藤沢薬品工業株式会社 | ペプチドの分子内ジスルフィド結合の形成法 |
| US5272135A (en) * | 1991-03-01 | 1993-12-21 | Chiron Ophthalmics, Inc. | Method for the stabilization of methionine-containing polypeptides |
| GB2451441B (en) | 2007-07-30 | 2012-07-11 | Lein Applied Diagnostics Ltd | Optical alignment apparatus and method thereof |
| KR102650195B1 (ko) | 2020-11-11 | 2024-04-09 | 주식회사 제론메드 | 유리 메티오닌ｒ설폭사이드를 정량적으로 측정할 수 있는 형광단백질 센서 및 이의 용도 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4745178A (en) * | 1987-04-22 | 1988-05-17 | Eli Lilly And Company | Process for selective peptide bond cleavage using sulfoxides and CF3 CO |
-
1987
- 1987-08-24 US US07/088,739 patent/US4835254A/en not_active Expired - Lifetime
-
1988
- 1988-08-12 CH CH3045/88A patent/CH675879A5/de not_active IP Right Cessation
- 1988-08-16 CA CA000574821A patent/CA1315482C/en not_active Expired - Fee Related
- 1988-08-17 NL NL8802041A patent/NL8802041A/nl not_active Application Discontinuation
- 1988-08-17 IL IL87479A patent/IL87479A/xx not_active IP Right Cessation
- 1988-08-18 IT IT8821716A patent/IT1226864B/it active
- 1988-08-19 KR KR1019880010521A patent/KR890003798A/ko not_active Ceased
- 1988-08-19 DE DE3828287A patent/DE3828287A1/de not_active Withdrawn
- 1988-08-19 SE SE8802941A patent/SE503255C2/sv not_active IP Right Cessation
- 1988-08-19 DK DK465588A patent/DK465588A/da unknown
- 1988-08-22 BE BE8800956A patent/BE1004198A3/fr not_active IP Right Cessation
- 1988-08-22 FR FR8811081A patent/FR2619820B1/fr not_active Expired - Lifetime
- 1988-08-22 GB GB8819861A patent/GB2209033B/en not_active Expired - Lifetime
- 1988-08-22 CN CN88106236A patent/CN1029976C/zh not_active Expired - Fee Related
- 1988-08-23 JP JP63209319A patent/JPH02262590A/ja active Pending
- 1988-08-23 HU HU884435A patent/HU200438B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL87479A0 (en) | 1989-01-31 |
| DK465588A (da) | 1989-03-17 |
| IT8821716A0 (it) | 1988-08-18 |
| GB2209033B (en) | 1991-01-02 |
| US4835254A (en) | 1989-05-30 |
| SE503255C2 (sv) | 1996-04-29 |
| JPH02262590A (ja) | 1990-10-25 |
| NL8802041A (nl) | 1989-03-16 |
| GB2209033A (en) | 1989-04-26 |
| KR890003798A (ko) | 1989-04-18 |
| CN1031538A (zh) | 1989-03-08 |
| DE3828287A1 (de) | 1989-03-09 |
| DK465588D0 (da) | 1988-08-19 |
| IT1226864B (it) | 1991-02-20 |
| BE1004198A3 (fr) | 1992-10-13 |
| FR2619820B1 (fr) | 1992-11-13 |
| FR2619820A1 (fr) | 1989-03-03 |
| CH675879A5 (ref) | 1990-11-15 |
| HU200438B (en) | 1990-06-28 |
| CN1029976C (zh) | 1995-10-11 |
| GB8819861D0 (en) | 1988-09-21 |
| SE8802941L (sv) | 1989-02-25 |
| HUT48560A (en) | 1989-06-28 |
| SE8802941D0 (sv) | 1988-08-19 |
| IL87479A (en) | 1993-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKLA | Lapsed |