CA1313872C - Acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
CA1313872C
CA1313872C CA000558388A CA558388A CA1313872C CA 1313872 C CA1313872 C CA 1313872C CA 000558388 A CA000558388 A CA 000558388A CA 558388 A CA558388 A CA 558388A CA 1313872 C CA1313872 C CA 1313872C
Authority
CA
Canada
Prior art keywords
radical
general formula
carbon atoms
substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000558388A
Other languages
English (en)
French (fr)
Inventor
Jean Lepagnol
Gilbert Lavielle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Servier de Medecine Translationnelle SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of CA1313872C publication Critical patent/CA1313872C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
CA000558388A 1987-02-27 1988-02-08 Acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent Expired - Fee Related CA1313872C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR87.02631 1987-02-27
FR8702631A FR2611715B1 (fr) 1987-02-27 1987-02-27 Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
CA1313872C true CA1313872C (fr) 1993-02-23

Family

ID=9348402

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000558388A Expired - Fee Related CA1313872C (fr) 1987-02-27 1988-02-08 Acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (16)

Country Link
US (1) US4812469A (enExample)
EP (1) EP0281471B1 (enExample)
JP (1) JPS63227583A (enExample)
AT (1) ATE53839T1 (enExample)
AU (1) AU598346B2 (enExample)
CA (1) CA1313872C (enExample)
DE (1) DE3860117D1 (enExample)
DK (1) DK163922C (enExample)
ES (1) ES2006336A6 (enExample)
FR (1) FR2611715B1 (enExample)
GR (1) GR1000161B (enExample)
IE (1) IE61990B1 (enExample)
NZ (1) NZ223664A (enExample)
OA (1) OA08719A (enExample)
PT (1) PT86852B (enExample)
ZA (1) ZA881384B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0474589A1 (de) * 1990-08-02 1992-03-11 Ciba-Geigy Ag Orthophenolacetamide
US20140315881A1 (en) * 2011-07-29 2014-10-23 Tempero Pharmaceuticals, Inc. Compounds and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB176309A (en) * 1921-03-03 1922-09-21 Mario Calderara Improvements in or relating to the renewal of electric incandescent lamps
US2472666A (en) * 1946-05-16 1949-06-07 Du Pont Production of dye intermediates
GB2044272B (en) * 1979-02-05 1983-03-16 Sandoz Ltd Stabilising polymers
US4618621A (en) * 1984-09-21 1986-10-21 The Upjohn Company Method for treating medical conditions involving cerebral ischemia
FR2593504B1 (fr) * 1986-01-30 1988-12-09 Ile De France Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques

Also Published As

Publication number Publication date
DK163922B (da) 1992-04-21
JPS63227583A (ja) 1988-09-21
GR1000161B (el) 1991-10-10
AU598346B2 (en) 1990-06-21
AU1234588A (en) 1988-09-01
FR2611715A1 (fr) 1988-09-09
OA08719A (fr) 1989-03-31
NZ223664A (en) 1989-09-27
IE880529L (en) 1988-08-27
DK163922C (da) 1992-09-21
FR2611715B1 (fr) 1989-05-12
GR880100112A (en) 1988-12-16
ATE53839T1 (de) 1990-06-15
US4812469A (en) 1989-03-14
ZA881384B (en) 1989-05-30
EP0281471B1 (fr) 1990-05-02
PT86852B (pt) 1992-05-29
IE61990B1 (en) 1994-12-14
EP0281471A1 (fr) 1988-09-07
DK104488D0 (da) 1988-02-26
PT86852A (pt) 1988-03-01
DE3860117D1 (de) 1990-06-07
ES2006336A6 (es) 1989-04-16
DK104488A (da) 1988-08-28
JPH0558634B2 (enExample) 1993-08-27

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