FR2611715B1 - Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2611715B1
FR2611715B1 FR8702631A FR8702631A FR2611715B1 FR 2611715 B1 FR2611715 B1 FR 2611715B1 FR 8702631 A FR8702631 A FR 8702631A FR 8702631 A FR8702631 A FR 8702631A FR 2611715 B1 FR2611715 B1 FR 2611715B1
Authority
FR
France
Prior art keywords
radical
dihydro
phenyl
derived
benzofurannone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8702631A
Other languages
English (en)
French (fr)
Other versions
FR2611715A1 (fr
Inventor
Gilbert Lavielle
Jean Lepagnol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Servier de Medecine Translationnelle SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Priority to FR8702631A priority Critical patent/FR2611715B1/fr
Priority to CA000558388A priority patent/CA1313872C/fr
Priority to US07/155,353 priority patent/US4812469A/en
Priority to JP63044082A priority patent/JPS63227583A/ja
Priority to DE8888400442T priority patent/DE3860117D1/de
Priority to IE52988A priority patent/IE61990B1/en
Priority to NZ223664A priority patent/NZ223664A/xx
Priority to PT86852A priority patent/PT86852B/pt
Priority to ZA881384A priority patent/ZA881384B/xx
Priority to AT88400442T priority patent/ATE53839T1/de
Priority to AU12345/88A priority patent/AU598346B2/en
Priority to GR880100112A priority patent/GR1000161B/el
Priority to DK104488A priority patent/DK163922C/da
Priority to EP88400442A priority patent/EP0281471B1/fr
Priority to OA59291A priority patent/OA08719A/xx
Priority to ES8800578A priority patent/ES2006336A6/es
Publication of FR2611715A1 publication Critical patent/FR2611715A1/fr
Application granted granted Critical
Publication of FR2611715B1 publication Critical patent/FR2611715B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
FR8702631A 1987-02-27 1987-02-27 Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent Expired FR2611715B1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR8702631A FR2611715B1 (fr) 1987-02-27 1987-02-27 Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
CA000558388A CA1313872C (fr) 1987-02-27 1988-02-08 Acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US07/155,353 US4812469A (en) 1987-02-27 1988-02-12 Acetamides derived from 2,3-dihydro-3-phenyl-2-benzofuranone
DK104488A DK163922C (da) 1987-02-27 1988-02-26 2,3-dihydro-3-phenyl-2-benzofuranonderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem
IE52988A IE61990B1 (en) 1987-02-27 1988-02-26 "New acetamides derived from 2,3-dihydro-3-phenyl-2-benzofuranone, processes for preparing them and the pharmaceutical compositions which contain them"
NZ223664A NZ223664A (en) 1987-02-27 1988-02-26 2,3-dihydro-3-phenyl-2-oxo-benzofuranylacetic acid amide derivatives and pharmaceutical compositions
PT86852A PT86852B (pt) 1987-02-27 1988-02-26 Processo para a preparacao de novas acetamidas derivadas da 2,3-dihidro-3-fenil-2-benzofuranona
ZA881384A ZA881384B (en) 1987-02-27 1988-02-26 Acetamides derived from 2,3-dihydro-3-phenyl-2-benzofuranone,processes for preparing them and the pharmaceutical compositions which contain them
JP63044082A JPS63227583A (ja) 1987-02-27 1988-02-26 ２，３−ジヒドロ−３−フエニル−２−ベンゾフラノン誘導体
AU12345/88A AU598346B2 (en) 1987-02-27 1988-02-26 New acetamides derived from 2,3-dihydro-3-phenyl-2-benzofuranone, processes for preparing them and the pharmaceutical compositions which contain them
GR880100112A GR1000161B (el) 1987-02-27 1988-02-26 Μεθοδος παρασκευης νεων ακεταμιδικων παραγωγων της διυδρο-2,3 φαινυλ-3 βενζοφουρανονης-2
DE8888400442T DE3860117D1 (de) 1987-02-27 1988-02-26 2,3-dihydro-3-phenyl-benzofuran-2-on-acetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
EP88400442A EP0281471B1 (fr) 1987-02-27 1988-02-26 Nouveaux acétamides dérivés de la dihydro-2,3 phényl-3 benzofurannone-2, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
OA59291A OA08719A (fr) 1987-02-27 1988-02-26 Nouveaux acétamides dérivés de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
AT88400442T ATE53839T1 (de) 1987-02-27 1988-02-26 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ES8800578A ES2006336A6 (es) 1987-02-27 1988-02-27 Procedimiento de preparacion de nuevas acetamidas derivadas de la 2,3-dihidro-3-fenil-2-benzofuranona.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8702631A FR2611715B1 (fr) 1987-02-27 1987-02-27 Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FR2611715A1 FR2611715A1 (fr) 1988-09-09
FR2611715B1 true FR2611715B1 (fr) 1989-05-12

Family

ID=9348402

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8702631A Expired FR2611715B1 (fr) 1987-02-27 1987-02-27 Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (16)

Country Link
US (1) US4812469A (enExample)
EP (1) EP0281471B1 (enExample)
JP (1) JPS63227583A (enExample)
AT (1) ATE53839T1 (enExample)
AU (1) AU598346B2 (enExample)
CA (1) CA1313872C (enExample)
DE (1) DE3860117D1 (enExample)
DK (1) DK163922C (enExample)
ES (1) ES2006336A6 (enExample)
FR (1) FR2611715B1 (enExample)
GR (1) GR1000161B (enExample)
IE (1) IE61990B1 (enExample)
NZ (1) NZ223664A (enExample)
OA (1) OA08719A (enExample)
PT (1) PT86852B (enExample)
ZA (1) ZA881384B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0474589A1 (de) * 1990-08-02 1992-03-11 Ciba-Geigy Ag Orthophenolacetamide
US20140315881A1 (en) * 2011-07-29 2014-10-23 Tempero Pharmaceuticals, Inc. Compounds and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB176309A (en) * 1921-03-03 1922-09-21 Mario Calderara Improvements in or relating to the renewal of electric incandescent lamps
US2472666A (en) * 1946-05-16 1949-06-07 Du Pont Production of dye intermediates
GB2044272B (en) * 1979-02-05 1983-03-16 Sandoz Ltd Stabilising polymers
US4618621A (en) * 1984-09-21 1986-10-21 The Upjohn Company Method for treating medical conditions involving cerebral ischemia
FR2593504B1 (fr) * 1986-01-30 1988-12-09 Ile De France Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques

Also Published As

Publication number Publication date
DK163922B (da) 1992-04-21
JPS63227583A (ja) 1988-09-21
GR1000161B (el) 1991-10-10
AU598346B2 (en) 1990-06-21
AU1234588A (en) 1988-09-01
FR2611715A1 (fr) 1988-09-09
OA08719A (fr) 1989-03-31
NZ223664A (en) 1989-09-27
IE880529L (en) 1988-08-27
DK163922C (da) 1992-09-21
GR880100112A (en) 1988-12-16
ATE53839T1 (de) 1990-06-15
US4812469A (en) 1989-03-14
ZA881384B (en) 1989-05-30
EP0281471B1 (fr) 1990-05-02
PT86852B (pt) 1992-05-29
IE61990B1 (en) 1994-12-14
EP0281471A1 (fr) 1988-09-07
DK104488D0 (da) 1988-02-26
PT86852A (pt) 1988-03-01
CA1313872C (fr) 1993-02-23
DE3860117D1 (de) 1990-06-07
ES2006336A6 (es) 1989-04-16
DK104488A (da) 1988-08-28
JPH0558634B2 (enExample) 1993-08-27

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Legal Events

Date Code Title Description
ST Notification of lapse