CA1309022C - Methode pour la preparation d'une composition pharmaceutique a liberation prolongee et la composition ainsi obtenue - Google Patents

Methode pour la preparation d'une composition pharmaceutique a liberation prolongee et la composition ainsi obtenue

Info

Publication number
CA1309022C
CA1309022C CA000534045A CA534045A CA1309022C CA 1309022 C CA1309022 C CA 1309022C CA 000534045 A CA000534045 A CA 000534045A CA 534045 A CA534045 A CA 534045A CA 1309022 C CA1309022 C CA 1309022C
Authority
CA
Canada
Prior art keywords
particles
process according
theophylline
composition
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000534045A
Other languages
English (en)
Inventor
Richard James Harwood
Gunvant Nathubhai Mehta
Ramesh Chandra Jhawar
Liang-Li Huang
Wayne Martin Grim
Shun Por Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Rhone Poulenc Rorer International Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer International Holdings Inc filed Critical Rhone Poulenc Rorer International Holdings Inc
Application granted granted Critical
Publication of CA1309022C publication Critical patent/CA1309022C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005Coating of tablets or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000534045A 1986-04-07 1987-04-07 Methode pour la preparation d'une composition pharmaceutique a liberation prolongee et la composition ainsi obtenue Expired - Lifetime CA1309022C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84899186A 1986-04-07 1986-04-07
US848,991 1986-04-07

Publications (1)

Publication Number Publication Date
CA1309022C true CA1309022C (fr) 1992-10-20

Family

ID=25304802

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000534045A Expired - Lifetime CA1309022C (fr) 1986-04-07 1987-04-07 Methode pour la preparation d'une composition pharmaceutique a liberation prolongee et la composition ainsi obtenue

Country Status (4)

Country Link
JP (1) JP2541835B2 (fr)
AU (1) AU7280387A (fr)
CA (1) CA1309022C (fr)
WO (1) WO1987006098A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162110A (en) * 1990-12-19 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Binding theophylline to ion exchange resins
US5744164A (en) * 1994-12-16 1998-04-28 Nestec S.A. Sustained release microparticulate caffeine formulation
SE505146C2 (sv) * 1995-10-19 1997-06-30 Biogram Ab Partiklar för fördröjd frisättning

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297088A (fr) * 1961-01-31
JPS57171429A (en) * 1981-04-13 1982-10-22 Glatt Gmbh Rotary disk type granulator
JPS58501128A (ja) * 1981-07-15 1983-07-14 キイ・フア−マシユ−テイカルズ・インコ−ポレイテツド 徐放性テオフイリン
US4600645A (en) * 1985-01-31 1986-07-15 Warner-Lambert Company Process for treating dosage forms

Also Published As

Publication number Publication date
JPH01501936A (ja) 1989-07-06
WO1987006098A1 (fr) 1987-10-22
JP2541835B2 (ja) 1996-10-09
AU7280387A (en) 1987-11-09

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Legal Events

Date Code Title Description
MKEX Expiry