CA1292593C - Polyetherurethane urea polymers as space filling tissue adhesives - Google Patents

Polyetherurethane urea polymers as space filling tissue adhesives

Info

Publication number
CA1292593C
CA1292593C CA000559548A CA559548A CA1292593C CA 1292593 C CA1292593 C CA 1292593C CA 000559548 A CA000559548 A CA 000559548A CA 559548 A CA559548 A CA 559548A CA 1292593 C CA1292593 C CA 1292593C
Authority
CA
Canada
Prior art keywords
methane
prepolymer
isocyanatocyclohexyl
compound
chain extending
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000559548A
Other languages
English (en)
French (fr)
Inventor
Nebojsa Nash Marinovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MTG Divestitures LLC
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1292593C publication Critical patent/CA1292593C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J175/00—Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
    • C09J175/04—Polyurethanes
    • C09J175/12—Polyurethanes from compounds containing nitrogen and active hydrogen, the nitrogen atom not being part of an isocyanate group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/75—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Sealing Material Composition (AREA)
CA000559548A 1987-02-25 1988-02-23 Polyetherurethane urea polymers as space filling tissue adhesives Expired - Lifetime CA1292593C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US018,546 1987-02-25
US07/018,546 US4743632A (en) 1987-02-25 1987-02-25 Polyetherurethane urea polymers as space filling tissue adhesives

Publications (1)

Publication Number Publication Date
CA1292593C true CA1292593C (en) 1991-11-26

Family

ID=21788490

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000559548A Expired - Lifetime CA1292593C (en) 1987-02-25 1988-02-23 Polyetherurethane urea polymers as space filling tissue adhesives

Country Status (8)

Country Link
US (1) US4743632A (enExample)
EP (1) EP0280451B1 (enExample)
JP (1) JPS63225681A (enExample)
AT (1) ATE80898T1 (enExample)
CA (1) CA1292593C (enExample)
DE (1) DE3874770T2 (enExample)
ES (1) ES2043804T3 (enExample)
GR (1) GR3006289T3 (enExample)

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US4829099A (en) * 1987-07-17 1989-05-09 Bioresearch, Inc. Metabolically acceptable polyisocyanate adhesives
EP0390481B1 (en) * 1989-03-23 1996-02-28 Sanyo Chemical Industries Ltd. Surgical adhesive sheet
DE4110316A1 (de) * 1991-03-28 1992-10-01 Uwe Storch Verwendung einer mischung fuer die herstellung von medizinischen implantaten
US5250652A (en) * 1992-07-30 1993-10-05 Lever Brothers Company, Division Of Conopco, Inc. High loading water-dispersible UVA and/or UVB light-absorbing copolymer
ZA935531B (en) * 1992-07-30 1995-01-30 Unilever Plc High loading water-dispersible UVA and/or UVB light-absorbing co-polymer
US6140452A (en) * 1994-05-06 2000-10-31 Advanced Bio Surfaces, Inc. Biomaterial for in situ tissue repair
US20050043808A1 (en) * 1994-05-06 2005-02-24 Advanced Bio Surfaces, Inc. Knee joint prosthesis
US5817303A (en) * 1995-05-05 1998-10-06 Protein Polymer Technologies, Inc. Bonding together tissue with adhesive containing polyfunctional crosslinking agent and protein polymer
JP2002505592A (ja) 1996-11-15 2002-02-19 アドバンスト バイオ サーフェイシズ，インコーポレイティド 生体内原位置で組織を修復するのに用いる生体用材料システム
US6302916B1 (en) * 1998-12-24 2001-10-16 Biopro, Inc. Polyurethane and so forth containing joints
US6626945B2 (en) * 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US6632246B1 (en) * 2000-03-14 2003-10-14 Chondrosite, Llc Cartilage repair plug
EP1315470B1 (en) 2000-08-28 2009-07-15 Disc Dynamics, Inc. System for mammalian joint resurfacing
US6524327B1 (en) * 2000-09-29 2003-02-25 Praxis, Llc In-situ bonds
AR032052A1 (es) * 2000-12-29 2003-10-22 Artimplant Ab Polimero lineal de bloques, procedimiento para su preparacion, su uso, implantes, material para relleno, composiciones farmaceuticas y material polimerico poroso que comprenden dicho polimero lineal de bloques
US20040068078A1 (en) * 2001-12-12 2004-04-08 Milbocker Michael T. In situ polymerizing medical compositions
US8501165B2 (en) * 2001-12-12 2013-08-06 Promethean Surgical Devices Llc In situ bonds
WO2003053278A2 (en) * 2001-12-19 2003-07-03 Advanced Bio Surfaces, Inc. Bone smoothing method and system
WO2003061522A2 (en) * 2002-01-22 2003-07-31 Advanced Bio Surfaces, Inc. Interpositional arthroplasty system and method
CA2492030A1 (en) * 2002-07-11 2004-01-22 Advanced Bio Surfaces, Inc. Method and kit for interpositional arthroplasty
HUP0203719A2 (en) * 2002-10-31 2007-09-28 Stepan Dr Gudak Polyuretan composition for fillin blood vessels and method of aplication of it
US20050215748A1 (en) * 2004-03-29 2005-09-29 Milbocker Michael T Surgical adhesive formulations and methods of preparation
US20060282169A1 (en) * 2004-12-17 2006-12-14 Felt Jeffrey C System and method for upper extremity joint arthroplasty
US20060195191A1 (en) * 2005-01-08 2006-08-31 Alphaspine Inc. Modular disc device
US7267690B2 (en) * 2005-03-09 2007-09-11 Vertebral Technologies, Inc. Interlocked modular disc nucleus prosthesis
CA2628580C (en) * 2005-12-06 2014-07-08 Tyco Healthcare Group Lp Bioabsorbable compounds and compositions containing them
EP2633834A1 (en) 2005-12-06 2013-09-04 Covidien LP Bioabsorbable Surgical Composition
AU2006321911B2 (en) * 2005-12-06 2012-05-17 Covidien Lp Biocompatible surgical compositions
CA2630327C (en) 2005-12-08 2015-05-26 Tyco Healthcare Group Lp Biocompatible surgical compositons
US9737414B2 (en) 2006-11-21 2017-08-22 Vertebral Technologies, Inc. Methods and apparatus for minimally invasive modular interbody fusion devices
US8043308B2 (en) * 2006-12-14 2011-10-25 Depuy Mitek, Inc. Bone suture
US7858835B2 (en) * 2007-06-27 2010-12-28 Tyco Healthcare Group Lp Foam control for synthetic adhesive/sealant
US8182647B2 (en) * 2007-07-23 2012-05-22 Cohera Medical, Inc. Hydrophilic biodegradable adhesives
US8500947B2 (en) * 2007-11-15 2013-08-06 Covidien Lp Speeding cure rate of bioadhesives
US8263704B2 (en) * 2008-04-23 2012-09-11 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US20110125158A1 (en) * 2008-05-01 2011-05-26 Ashish Dhar Diwan Systems, methods and apparatuses for formation and insertion of tissue prostheses
US9510953B2 (en) 2012-03-16 2016-12-06 Vertebral Technologies, Inc. Modular segmented disc nucleus implant

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2929804A (en) * 1955-01-31 1960-03-22 Du Pont Elastic filaments of linear segmented polymers
GB930458A (en) * 1960-11-23 1963-07-03 Ici Ltd Process for the purification of isocyanate group-containing compounds
US3415790A (en) * 1964-06-29 1968-12-10 Eastman Kodak Co Removing unreacted diisocyanates from macrodiisocyanates and polymerizing to form segmented polyurethane copolymers
US3384624A (en) * 1965-03-01 1968-05-21 Mobay Chemical Corp Prepolymer composition
US3271352A (en) * 1965-03-09 1966-09-06 Johnson & Johnson Polyurethane coating from mixed polyurethane polymers
CH1209368D (enExample) * 1967-09-18
US3752786A (en) * 1971-11-05 1973-08-14 Usm Corp Polyurethane polyureas
IT967742B (it) * 1972-09-22 1974-03-11 Montedison Spa Procedimento per la preparazione di poliisocianati ad alto peso molecolare
IN141398B (enExample) * 1973-05-16 1977-02-26 Ethicon Inc
US4169175A (en) * 1976-06-14 1979-09-25 W. R. Grace & Co. Removal of unreacted tolylene diisocyanate from urethane prepolymers
DE3203775A1 (de) * 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
US4385171A (en) * 1982-04-30 1983-05-24 Olin Corporation Research Center Removal of unreacted diisocyanate from polyurethane prepolymers
CA1205745A (en) * 1982-07-02 1986-06-10 John D. Dell Film-forming composition containing an antimicrobial agent and method
US4477604A (en) * 1982-09-20 1984-10-16 Oechsle Iii Sixtus J Polyurethane compositions and their use as luting agents
IT1153909B (it) * 1982-12-17 1987-01-21 Sogimi Srl Polimeri reattivi per la cura di affezioni cutanee
JPS61200114A (ja) * 1985-02-28 1986-09-04 Nippon Zeon Co Ltd 抗血栓性ポリウレタン化合物及びその製造方法
DD251565B5 (de) * 1986-07-29 1995-10-19 Basf Schwarzheide Gmbh Verfahren zur Herstellung physiologisch unbedenklicher Polyurethanformstoffe

Also Published As

Publication number Publication date
EP0280451A2 (en) 1988-08-31
DE3874770T2 (de) 1993-02-04
JPH0583110B2 (enExample) 1993-11-24
ES2043804T3 (es) 1994-01-01
DE3874770D1 (de) 1992-10-29
EP0280451A3 (en) 1989-11-29
JPS63225681A (ja) 1988-09-20
US4743632A (en) 1988-05-10
GR3006289T3 (enExample) 1993-06-21
ATE80898T1 (de) 1992-10-15
EP0280451B1 (en) 1992-09-23

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