CA1271966C - Les aryl-et aralarylsulfonyl-l-prolines - Google Patents

Les aryl-et aralarylsulfonyl-l-prolines

Info

Publication number
CA1271966C
CA1271966C CA615516A CA615516A CA1271966C CA 1271966 C CA1271966 C CA 1271966C CA 615516 A CA615516 A CA 615516A CA 615516 A CA615516 A CA 615516A CA 1271966 C CA1271966 C CA 1271966C
Authority
CA
Canada
Prior art keywords
prolines
aryl
formula
aralkyl sulfonyl
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA615516A
Other languages
English (en)
Other versions
CA1271966A (fr
Inventor
John Krapcho
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA615516A priority Critical patent/CA1271966C/fr
Application granted granted Critical
Publication of CA1271966A publication Critical patent/CA1271966A/fr
Publication of CA1271966C publication Critical patent/CA1271966C/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA615516A 1983-04-25 1984-04-17 Les aryl-et aralarylsulfonyl-l-prolines Expired CA1271966C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA615516A CA1271966C (fr) 1983-04-25 1984-04-17 Les aryl-et aralarylsulfonyl-l-prolines

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48847783A 1983-04-25 1983-04-25
US488,477 1983-04-25
CA615516A CA1271966C (fr) 1983-04-25 1984-04-17 Les aryl-et aralarylsulfonyl-l-prolines
CA000452213A CA1266661A (fr) 1983-04-25 1984-04-17 Derives acylmercaptoalcanoyle et mercaptoalcanoyle d'aryl- et d'aralcoylsulfinyl- ou sulfonyl-l- prolines

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA000452213A Division CA1266661A (fr) 1983-04-25 1984-04-17 Derives acylmercaptoalcanoyle et mercaptoalcanoyle d'aryl- et d'aralcoylsulfinyl- ou sulfonyl-l- prolines

Publications (2)

Publication Number Publication Date
CA1271966A CA1271966A (fr) 1990-07-24
CA1271966C true CA1271966C (fr) 1990-07-24

Family

ID=34117156

Family Applications (2)

Application Number Title Priority Date Filing Date
CA615516A Expired CA1271966C (fr) 1983-04-25 1984-04-17 Les aryl-et aralarylsulfonyl-l-prolines
CA000452213A Expired - Lifetime CA1266661A (fr) 1983-04-25 1984-04-17 Derives acylmercaptoalcanoyle et mercaptoalcanoyle d'aryl- et d'aralcoylsulfinyl- ou sulfonyl-l- prolines

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA000452213A Expired - Lifetime CA1266661A (fr) 1983-04-25 1984-04-17 Derives acylmercaptoalcanoyle et mercaptoalcanoyle d'aryl- et d'aralcoylsulfinyl- ou sulfonyl-l- prolines

Country Status (1)

Country Link
CA (2) CA1271966C (fr)

Also Published As

Publication number Publication date
CA1266661C (fr) 1990-03-13
CA1271966A (fr) 1990-07-24
CA1266661A (fr) 1990-03-13

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Legal Events

Date Code Title Description
MKLA Lapsed
MKLA Lapsed

Effective date: 20020724