CA1268208A - Magnetic micro-particles as contrast agents in nuclear magnetic resonance imaging - Google Patents
Magnetic micro-particles as contrast agents in nuclear magnetic resonance imagingInfo
- Publication number
- CA1268208A CA1268208A CA000485587A CA485587A CA1268208A CA 1268208 A CA1268208 A CA 1268208A CA 000485587 A CA000485587 A CA 000485587A CA 485587 A CA485587 A CA 485587A CA 1268208 A CA1268208 A CA 1268208A
- Authority
- CA
- Canada
- Prior art keywords
- tissue
- magnetic
- micro
- particles
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64003784A | 1984-08-10 | 1984-08-10 | |
US640,037 | 1984-08-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1268208A true CA1268208A (en) | 1990-04-24 |
Family
ID=24566571
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000485587A Expired - Fee Related CA1268208A (en) | 1984-08-10 | 1985-06-27 | Magnetic micro-particles as contrast agents in nuclear magnetic resonance imaging |
Country Status (4)
Country | Link |
---|---|
CA (1) | CA1268208A (de) |
DE (1) | DE3590398T1 (de) |
GB (1) | GB2177199A (de) |
WO (1) | WO1986001112A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62181229A (ja) * | 1985-11-05 | 1987-08-08 | ザ・ゼネラル・ホスピタル・コ−ポレ−シヨン | 負に荷電した特異親和性試薬 |
US5223242A (en) * | 1985-11-05 | 1993-06-29 | The General Hospital Corporation | Negatively charged specific affinity reagents |
US5314679A (en) * | 1986-07-03 | 1994-05-24 | Advanced Magnetics Inc. | Vascular magnetic resonance imaging agent comprising nanoparticles |
US5055288A (en) * | 1987-06-26 | 1991-10-08 | Advanced Magnetics, Inc. | Vascular magnetic imaging method and agent comprising biodegradeable superparamagnetic metal oxides |
FR2612400A1 (fr) * | 1987-03-16 | 1988-09-23 | Centre Nat Rech Scient | Microcapsules contenant un marqueur radioactif et/ou paramagnetique sous forme de chelate, et leur utilisation dans le domaine de l'imagerie medicale |
DE3709851A1 (de) * | 1987-03-24 | 1988-10-06 | Silica Gel Gmbh Adsorptions Te | Nmr-diagnostische fluessigkeitszusammensetzungen |
US5314681A (en) * | 1988-12-23 | 1994-05-24 | Nycomed Innovation Ab | Composition of positive and negative contrast agents for electron spin resonance enhanced magnetic resonance imaging |
US5164297A (en) * | 1990-05-03 | 1992-11-17 | Advanced Magnetics Inc. | Solvent mediated relaxation assay system |
US5948384A (en) * | 1990-09-14 | 1999-09-07 | Syngenix Limited | Particulate agents |
WO1992004916A2 (en) * | 1990-09-14 | 1992-04-02 | St. George's Enterprises Limited | Particulate agents |
GB9020075D0 (en) | 1990-09-14 | 1990-10-24 | Filler Aaron G | Contrast agents for magnetic resonance imaging of axonal transport |
US6919067B2 (en) | 1991-09-13 | 2005-07-19 | Syngenix Limited | Compositions comprising a tissue glue and therapeutic agents |
DE4309333A1 (de) * | 1993-03-17 | 1994-09-22 | Silica Gel Gmbh | Superparamagnetische Teilchen, Verfahren zu ihrer Herstellung und Verwendung derselben |
DE69628731T3 (de) * | 1995-11-01 | 2012-09-20 | Bracco Suisse S.A. | Gezielte magnetisch markierte molekularmarkersysteme als nmr-bilderzeugungsmittel |
ATE291439T1 (de) | 1996-01-10 | 2005-04-15 | Amersham Health As | Kontrastmittel |
GB9600427D0 (en) * | 1996-01-10 | 1996-03-13 | Nycomed Imaging As | Contrast media |
WO2006124726A2 (en) | 2005-05-12 | 2006-11-23 | The General Hospital Corporation | Novel biotinylated compositions |
CA2883130A1 (en) | 2012-08-31 | 2014-03-06 | The General Hospital Corporation | Biotin complexes for treatment and diagnosis of alzheimer's disease |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
US4452773A (en) * | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
US4454106A (en) * | 1982-06-07 | 1984-06-12 | Gansow Otto A | Use of metal chelate conjugated monoclonal antibodies |
-
1985
- 1985-06-27 CA CA000485587A patent/CA1268208A/en not_active Expired - Fee Related
- 1985-08-06 DE DE19853590398 patent/DE3590398T1/de not_active Withdrawn
- 1985-08-06 WO PCT/US1985/001495 patent/WO1986001112A1/en active Application Filing
- 1985-08-06 GB GB08607629A patent/GB2177199A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE3590398T1 (de) | 1986-08-28 |
GB2177199A (en) | 1987-01-14 |
WO1986001112A1 (en) | 1986-02-27 |
GB8607629D0 (en) | 1986-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKLA | Lapsed |