CA1268208A - Micro-particules magnetiques servant d'agents de contraste en imagerie a resonance magnetique nucleaire - Google Patents

Micro-particules magnetiques servant d'agents de contraste en imagerie a resonance magnetique nucleaire

Info

Publication number
CA1268208A
CA1268208A CA000485587A CA485587A CA1268208A CA 1268208 A CA1268208 A CA 1268208A CA 000485587 A CA000485587 A CA 000485587A CA 485587 A CA485587 A CA 485587A CA 1268208 A CA1268208 A CA 1268208A
Authority
CA
Canada
Prior art keywords
tissue
magnetic
micro
particles
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000485587A
Other languages
English (en)
Inventor
Truman Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fox Chase Cancer Center
Original Assignee
Fox Chase Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fox Chase Cancer Center filed Critical Fox Chase Cancer Center
Application granted granted Critical
Publication of CA1268208A publication Critical patent/CA1268208A/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
CA000485587A 1984-08-10 1985-06-27 Micro-particules magnetiques servant d'agents de contraste en imagerie a resonance magnetique nucleaire Expired - Fee Related CA1268208A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64003784A 1984-08-10 1984-08-10
US640,037 1984-08-10

Publications (1)

Publication Number Publication Date
CA1268208A true CA1268208A (fr) 1990-04-24

Family

ID=24566571

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000485587A Expired - Fee Related CA1268208A (fr) 1984-08-10 1985-06-27 Micro-particules magnetiques servant d'agents de contraste en imagerie a resonance magnetique nucleaire

Country Status (4)

Country Link
CA (1) CA1268208A (fr)
DE (1) DE3590398T1 (fr)
GB (1) GB2177199A (fr)
WO (1) WO1986001112A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223242A (en) * 1985-11-05 1993-06-29 The General Hospital Corporation Negatively charged specific affinity reagents
EP0268707A3 (fr) * 1985-11-05 1989-03-08 The General Hospital Corporation Réactifs d'affinité spécifique portant une charge négative
US5055288A (en) * 1987-06-26 1991-10-08 Advanced Magnetics, Inc. Vascular magnetic imaging method and agent comprising biodegradeable superparamagnetic metal oxides
US5314679A (en) * 1986-07-03 1994-05-24 Advanced Magnetics Inc. Vascular magnetic resonance imaging agent comprising nanoparticles
FR2612400A1 (fr) * 1987-03-16 1988-09-23 Centre Nat Rech Scient Microcapsules contenant un marqueur radioactif et/ou paramagnetique sous forme de chelate, et leur utilisation dans le domaine de l'imagerie medicale
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
US5314681A (en) * 1988-12-23 1994-05-24 Nycomed Innovation Ab Composition of positive and negative contrast agents for electron spin resonance enhanced magnetic resonance imaging
US5164297A (en) * 1990-05-03 1992-11-17 Advanced Magnetics Inc. Solvent mediated relaxation assay system
EP0548157B1 (fr) * 1990-09-14 1998-05-20 Syngenix Limited Utilisation d'agents sous forme de particules
US5948384A (en) * 1990-09-14 1999-09-07 Syngenix Limited Particulate agents
GB9020075D0 (en) * 1990-09-14 1990-10-24 Filler Aaron G Contrast agents for magnetic resonance imaging of axonal transport
US6919067B2 (en) 1991-09-13 2005-07-19 Syngenix Limited Compositions comprising a tissue glue and therapeutic agents
DE4309333A1 (de) * 1993-03-17 1994-09-22 Silica Gel Gmbh Superparamagnetische Teilchen, Verfahren zu ihrer Herstellung und Verwendung derselben
DE69628731T3 (de) * 1995-11-01 2012-09-20 Bracco Suisse S.A. Gezielte magnetisch markierte molekularmarkersysteme als nmr-bilderzeugungsmittel
GB9600427D0 (en) * 1996-01-10 1996-03-13 Nycomed Imaging As Contrast media
AU716667B2 (en) 1996-01-10 2000-03-02 Nycomed Imaging As Contrast media
WO2006124726A2 (fr) 2005-05-12 2006-11-23 The General Hospital Corporation Nouvelles compositions biotinylatees
WO2014036427A1 (fr) 2012-08-31 2014-03-06 The General Hospital Corporation Complexes de biotine pour le traitement et le diagnostic de la maladie d'alzheimer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US4454106A (en) * 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies

Also Published As

Publication number Publication date
WO1986001112A1 (fr) 1986-02-27
DE3590398T1 (de) 1986-08-28
GB2177199A (en) 1987-01-14
GB8607629D0 (en) 1986-04-30

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