CA1268117A - Capsule loading technique - Google Patents

Capsule loading technique

Info

Publication number
CA1268117A
CA1268117A CA000507919A CA507919A CA1268117A CA 1268117 A CA1268117 A CA 1268117A CA 000507919 A CA000507919 A CA 000507919A CA 507919 A CA507919 A CA 507919A CA 1268117 A CA1268117 A CA 1268117A
Authority
CA
Canada
Prior art keywords
capsules
membrane
loading
solute
capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000507919A
Other languages
English (en)
French (fr)
Inventor
Wen-Ghih Tsang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Biotech Inc
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Application granted granted Critical
Publication of CA1268117A publication Critical patent/CA1268117A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/203—Exchange of core-forming material by diffusion through the capsule wall
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA000507919A 1985-07-03 1986-04-29 Capsule loading technique Expired - Lifetime CA1268117A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/752,384 US4683092A (en) 1985-07-03 1985-07-03 Capsule loading technique
US752,384 1985-07-03

Publications (1)

Publication Number Publication Date
CA1268117A true CA1268117A (en) 1990-04-24

Family

ID=25026104

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000507919A Expired - Lifetime CA1268117A (en) 1985-07-03 1986-04-29 Capsule loading technique

Country Status (8)

Country Link
US (1) US4683092A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0207655B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPS627441A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE46625T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1268117A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3665818D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK304186A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO862689L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (45)

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US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
JPH0753656B2 (ja) * 1986-05-14 1995-06-07 ライオン株式会社 浴用組成物
US4997599A (en) * 1987-12-08 1991-03-05 Celanese Fibers Inc. Preparation of water soluble cellulose acetate microspheres
US4970031A (en) * 1988-06-02 1990-11-13 Nok Corporation Process for preparing microcapsules with controlled-release
JP2733087B2 (ja) * 1989-03-29 1998-03-30 花王株式会社 中空ポリマー微粒子及びその製造方法並びにその用途
JPH02258053A (ja) * 1989-03-31 1990-10-18 Mita Ind Co Ltd 単核含水マイクロカプセルの製造方法
JPH02258052A (ja) * 1989-03-31 1990-10-18 Mita Ind Co Ltd 芯物質の保持性に優れた含水マイクロカプセルの製造方法
GB8926320D0 (en) * 1989-11-21 1990-01-10 Univ Strathclyde Production of microparticles
US5305757A (en) * 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5714167A (en) * 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US6461643B2 (en) * 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CN1151836C (zh) * 1995-03-31 2004-06-02 艾米斯菲尔技术有限公司 用作传送活性剂的化合物和组合物
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO1997036480A1 (en) 1996-03-29 1997-10-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
DE19681560T1 (de) * 1995-09-11 1998-08-20 Emisphere Tech Inc Verfahren zur Herstellung von omega-Aminoalkansäure-Derivaten aus Cycloalkanonen
US6447800B2 (en) 1996-01-18 2002-09-10 The University Of British Columbia Method of loading preformed liposomes using ethanol
AU3828597A (en) 1996-06-14 1998-01-07 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
US6030641A (en) * 1997-06-03 2000-02-29 Uni Colloid Kabushiki Kaisha Sustained release capsule and method for preparing the same
US20010003580A1 (en) * 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
EP1867325B1 (de) * 1998-03-19 2011-09-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kapseln enthaltend Lipide in der Hülle
US7101575B2 (en) * 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
US6701637B2 (en) 2001-04-20 2004-03-09 Kimberly-Clark Worldwide, Inc. Systems for tissue dried with metal bands
CA2456073A1 (en) * 2001-08-03 2003-02-20 Maripro As Improvements in or relating to encapsulation
AU2003251858A1 (en) * 2002-07-11 2004-02-02 Targeson, Llc Microbubble compositions, and methods for preparing and using same
DE102004013637A1 (de) * 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Verfahren zur Herstellung von CS-Partikeln und Mikrokapseln unter Verwendung poröser Template sowie CS-Partikel und Mikrokapseln
ITRM20080037A1 (it) 2008-01-23 2009-07-24 Uni Degli Studi Perugia Procedimento per la ultrapurificazione di alginati.
JP5443780B2 (ja) * 2009-02-20 2014-03-19 積水化学工業株式会社 イミダゾール化合物を内包した微粒子の製造方法
NZ599527A (en) 2009-11-09 2014-04-30 Spotlight Technology Partners Llc Fragmented hydrogels
EP2498763A4 (en) 2009-11-09 2015-10-07 Spotlight Technology Partners Llc HYDROGELE ON POLYSACCHARIDBASIS

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3516942A (en) * 1966-09-27 1970-06-23 Ncr Co Process for drying capsule walls of hydrophilic polymeric material
US3516943A (en) * 1966-12-06 1970-06-23 Ncr Co Replacement of capsule contents by diffusion
US3657144A (en) * 1967-06-05 1972-04-18 Ncr Co Encapsulation process
US3639306A (en) * 1968-08-08 1972-02-01 Amicon Corp Encapsulating particles and process for making same
US3664963A (en) * 1969-10-22 1972-05-23 Balchem Corp Encapsulation process
US3780195A (en) * 1969-10-22 1973-12-18 Balchem Corp Encapsulation process
US3657143A (en) * 1970-02-02 1972-04-18 Ncr Co Manufacture of minute capsules enmasse and dewatering their walls
US3639036A (en) * 1970-04-13 1972-02-01 Edward J Rosebach Jr Light-reflective wheel covers
JPS5211184A (en) * 1975-07-17 1977-01-27 Yoshiaki Motozato Two-layer spherical gel particles for molecular sieve
US4324683A (en) * 1975-08-20 1982-04-13 Damon Corporation Encapsulation of labile biological material
JPS5248574A (en) * 1975-10-16 1977-04-18 Toyo Jozo Co Ltd Process for refining
JPS6017573B2 (ja) * 1977-05-04 1985-05-04 神崎製紙株式会社 マイクロカプセル水性分散液の製造法
JPS588292B2 (ja) * 1978-03-09 1983-02-15 工業技術院長 マイクロカプセルの調製方法
US4272398A (en) * 1978-08-17 1981-06-09 The United States Of America As Represented By The Secretary Of Agriculture Microencapsulation process
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4389419A (en) * 1980-11-10 1983-06-21 Damon Corporation Vitamin encapsulation
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
AU567155B2 (en) * 1983-04-15 1987-11-12 Damon Biotech Inc. Capsules for releasing core material at constant rate
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
JPS6034731A (ja) * 1983-08-04 1985-02-22 Kohjin Co Ltd 新規なマイクロカプセルとその製造方法
US4492720A (en) * 1983-11-15 1985-01-08 Benjamin Mosier Method of preparing microspheres for intravascular delivery

Also Published As

Publication number Publication date
ATE46625T1 (de) 1989-10-15
DK304186A (da) 1987-01-04
EP0207655B1 (en) 1989-09-27
JPS627441A (ja) 1987-01-14
NO862689D0 (no) 1986-07-02
NO862689L (no) 1987-01-05
US4683092A (en) 1987-07-28
DK304186D0 (da) 1986-06-26
JPH02290241A (ja) 1990-11-30
EP0207655A1 (en) 1987-01-07
DE3665818D1 (en) 1989-11-02
JPH0516900B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-03-05

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Legal Events

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