CA1266864A - Radiopharmaceuticals and chelating agents useful in their preparation - Google Patents
Radiopharmaceuticals and chelating agents useful in their preparationInfo
- Publication number
- CA1266864A CA1266864A CA000487166A CA487166A CA1266864A CA 1266864 A CA1266864 A CA 1266864A CA 000487166 A CA000487166 A CA 000487166A CA 487166 A CA487166 A CA 487166A CA 1266864 A CA1266864 A CA 1266864A
- Authority
- CA
- Canada
- Prior art keywords
- formula
- alkyl
- compound
- salt
- zero
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Conversion Of X-Rays Into Visible Images (AREA)
- Luminescent Compositions (AREA)
- Glass Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63238384A | 1984-07-19 | 1984-07-19 | |
| US632,383 | 1984-07-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1266864A true CA1266864A (en) | 1990-03-20 |
Family
ID=24535323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000487166A Expired - Lifetime CA1266864A (en) | 1984-07-19 | 1985-07-19 | Radiopharmaceuticals and chelating agents useful in their preparation |
Country Status (14)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0322876A3 (en) * | 1987-12-29 | 1990-09-05 | Nihon Medi-Physics Co., Ltd. | Chelating compounds and their use |
| SE526214C2 (sv) * | 2003-02-28 | 2005-07-26 | Amersham Biosciences Ab | Ett sätt att generera metallkelaterande affinitetsligander |
| KR101033209B1 (ko) * | 2004-12-31 | 2011-05-06 | 주식회사 효성 | 분사성을 향상시킨 폴리에스테르 분섬사의 제조방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444690A (en) * | 1982-02-25 | 1984-04-24 | University Patents, Inc. | Technetium chelates |
| EP0221588A3 (en) * | 1982-05-18 | 1988-09-21 | University Of Florida | Brain-specific drug delivery |
-
1985
- 1985-07-15 EP EP85903750A patent/EP0191788A1/en not_active Withdrawn
- 1985-07-15 WO PCT/US1985/001333 patent/WO1986000897A1/en not_active Application Discontinuation
- 1985-07-15 AU AU46320/85A patent/AU4632085A/en not_active Abandoned
- 1985-07-18 IL IL75845A patent/IL75845A0/xx unknown
- 1985-07-18 GR GR851793A patent/GR851793B/el unknown
- 1985-07-18 KR KR8505136A patent/KR900008168B1/ko not_active Expired
- 1985-07-19 ES ES545395A patent/ES8700236A1/es not_active Expired
- 1985-07-19 PT PT80842A patent/PT80842B/pt unknown
- 1985-07-19 JP JP60160039A patent/JPS61112054A/ja active Pending
- 1985-07-19 CA CA000487166A patent/CA1266864A/en not_active Expired - Lifetime
- 1985-07-19 ZA ZA855477A patent/ZA855477B/xx unknown
-
1986
- 1986-02-17 ES ES552090A patent/ES8705389A1/es not_active Expired
- 1986-03-14 NO NO860980A patent/NO860980L/no unknown
- 1986-03-18 DK DK124686A patent/DK124686A/da not_active Application Discontinuation
- 1986-03-18 FI FI861119A patent/FI861119A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES8700236A1 (es) | 1986-10-01 |
| ES545395A0 (es) | 1986-10-01 |
| IL75845A0 (en) | 1985-11-29 |
| EP0191788A1 (en) | 1986-08-27 |
| AU4632085A (en) | 1986-02-25 |
| ES552090A0 (es) | 1987-05-01 |
| JPS61112054A (ja) | 1986-05-30 |
| NO860980L (no) | 1986-05-06 |
| WO1986000897A1 (en) | 1986-02-13 |
| DK124686D0 (da) | 1986-03-18 |
| KR870000935A (ko) | 1987-03-10 |
| DK124686A (da) | 1986-05-20 |
| ZA855477B (en) | 1987-03-25 |
| ES8705389A1 (es) | 1987-05-01 |
| GR851793B (enrdf_load_stackoverflow) | 1985-11-26 |
| FI861119A0 (fi) | 1986-03-18 |
| KR900008168B1 (en) | 1990-11-05 |
| PT80842B (en) | 1987-05-27 |
| PT80842A (en) | 1985-08-01 |
| FI861119A7 (fi) | 1986-03-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4963688A (en) | Compounds for site-enhanced delivery of radionuclides and uses thereof | |
| US5484893A (en) | Tri-aza macrocycles and metal complexes thereof | |
| DE3855177T2 (de) | Makrozyklische tetraaza-verbindungen | |
| EP0108406B1 (en) | Bifunctional chelating agents | |
| US4571430A (en) | Homocysteine and homocysteinamide derivatives | |
| US4575556A (en) | Bifunctional chelating agents | |
| CA3222226A1 (en) | Trislinker-conjugated dimeric labeling precursors and radiotracers derived therefrom | |
| US4963682A (en) | Novel radiopharmaceuticals and chelating agents useful in their preparation | |
| US5374416A (en) | Nitrogenous macrocyclic ligands, polymetallic complexes and diagnostic and therapeutic composition | |
| DE68918447T2 (de) | Bifunktionelle kuppler und daraus hergestellte mit radionukleid markierte zusammensetzungen. | |
| US5175257A (en) | Radiolabeled proteins for diagnostic or therapeutic use | |
| CA1266864A (en) | Radiopharmaceuticals and chelating agents useful in their preparation | |
| US5250666A (en) | Radionuclide metal chelates for the radiolabeling of proteins | |
| KR900007514B1 (ko) | 금속 방사성 핵종과 함께 킬레이트 할수 있는 염 | |
| US5136038A (en) | Radiopharmaceuticals and chelating agents useful in their preparation | |
| DE19860289C2 (de) | Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium | |
| US5247077A (en) | Tri-aza macrocycles and processes for their preparation | |
| US5155227A (en) | Compounds for site-enhanced delivery of radionuclides | |
| DE69515302T2 (de) | Aromatische aminsubstituierte liganden mit verbrückten stickstoff-und schwefeldonatoratomen für bildformung | |
| US6024937A (en) | Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging | |
| DE69023616T2 (de) | Radionukleid-chelatverbindungen zur radiomarkierung von proteinen. | |
| US5656253A (en) | Ligands useful in radiographic imaging | |
| US7731936B2 (en) | Metal complexes based on tetrathiol ligands and their use in nuclear medical diagnostics and endoradionuclide therapy and method for producing said metal complexes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKLA | Lapsed |