CA1233119A - Method for preparing a galenic form for oral administration by lyophilization of an oil-in-water emulsion - Google Patents

Method for preparing a galenic form for oral administration by lyophilization of an oil-in-water emulsion

Info

Publication number
CA1233119A
CA1233119A CA000476784A CA476784A CA1233119A CA 1233119 A CA1233119 A CA 1233119A CA 000476784 A CA000476784 A CA 000476784A CA 476784 A CA476784 A CA 476784A CA 1233119 A CA1233119 A CA 1233119A
Authority
CA
Canada
Prior art keywords
aqueous phase
phase
weight
lipid
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000476784A
Other languages
English (en)
French (fr)
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of CA1233119A publication Critical patent/CA1233119A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
CA000476784A 1984-03-30 1985-03-18 Method for preparing a galenic form for oral administration by lyophilization of an oil-in-water emulsion Expired CA1233119A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8405058 1984-03-30
FR8405058A FR2561916B1 (fr) 1984-03-30 1984-03-30 Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau

Publications (1)

Publication Number Publication Date
CA1233119A true CA1233119A (en) 1988-02-23

Family

ID=9302670

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000476784A Expired CA1233119A (en) 1984-03-30 1985-03-18 Method for preparing a galenic form for oral administration by lyophilization of an oil-in-water emulsion

Country Status (10)

Country Link
US (1) US4616047A (OSRAM)
EP (1) EP0159237B1 (OSRAM)
JP (1) JPS60224617A (OSRAM)
AT (1) ATE34078T1 (OSRAM)
AU (1) AU567271B2 (OSRAM)
CA (1) CA1233119A (OSRAM)
DE (1) DE3562555D1 (OSRAM)
ES (1) ES8607011A1 (OSRAM)
FR (1) FR2561916B1 (OSRAM)
ZA (1) ZA852168B (OSRAM)

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Also Published As

Publication number Publication date
US4616047A (en) 1986-10-07
EP0159237A1 (en) 1985-10-23
ATE34078T1 (de) 1988-05-15
FR2561916A1 (fr) 1985-10-04
JPS60224617A (ja) 1985-11-09
AU567271B2 (en) 1987-11-12
ES542483A0 (es) 1986-05-16
JPH0581567B2 (OSRAM) 1993-11-15
EP0159237B1 (en) 1988-05-11
ES8607011A1 (es) 1986-05-16
FR2561916B1 (fr) 1987-12-11
AU4015385A (en) 1985-10-03
ZA852168B (en) 1985-11-27
DE3562555D1 (en) 1988-06-16

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