CA1215969A - Cephem compounds and processes for preparation thereof - Google Patents

Cephem compounds and processes for preparation thereof

Info

Publication number
CA1215969A
CA1215969A CA000361999A CA361999A CA1215969A CA 1215969 A CA1215969 A CA 1215969A CA 000361999 A CA000361999 A CA 000361999A CA 361999 A CA361999 A CA 361999A CA 1215969 A CA1215969 A CA 1215969A
Authority
CA
Canada
Prior art keywords
amino
pharmaceutically acceptable
cephem
acceptable salts
obvious chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000361999A
Other languages
English (en)
French (fr)
Inventor
Tsutomu Teraji
Jiro Goto
Kazuo Sakane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK554279A external-priority patent/DK554279A/da
Priority claimed from US06/160,904 external-priority patent/US4381299A/en
Priority claimed from US06/180,295 external-priority patent/US4338313A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1215969A publication Critical patent/CA1215969A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/21—Radicals derived from sulfur analogues of carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000361999A 1979-10-12 1980-10-08 Cephem compounds and processes for preparation thereof Expired CA1215969A (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GB7935538 1979-10-12
GB7935538 1979-10-12
DK554279A DK554279A (da) 1978-12-29 1979-12-21 Fremgangsmaade til fremstilling af cepham- og cephemderivater
DK5542/79 1979-12-21
US06/128,260 US4331665A (en) 1978-12-29 1980-03-07 Cephem and cepham compounds
US128,260 1980-03-07
US06/160,904 US4381299A (en) 1980-03-07 1980-06-18 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds
US160,904 1980-06-18
US06/180,295 US4338313A (en) 1979-10-12 1980-08-22 Cephem compounds
US180,295 1980-08-22
AU23283/84A AU2328384A (en) 1978-12-29 1984-01-13 1,2,4-thiadiazole derivatives

Publications (1)

Publication Number Publication Date
CA1215969A true CA1215969A (en) 1986-12-30

Family

ID=32966828

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000361999A Expired CA1215969A (en) 1979-10-12 1980-10-08 Cephem compounds and processes for preparation thereof

Country Status (5)

Country Link
EP (1) EP0027599B1 (enExample)
JP (4) JPS57112396A (enExample)
CA (1) CA1215969A (enExample)
DE (1) DE3069364D1 (enExample)
HU (1) HU185014B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1215969A (en) * 1979-10-12 1986-12-30 Tsutomu Teraji Cephem compounds and processes for preparation thereof
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
GR75644B (enExample) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
ZA813787B (en) * 1980-06-18 1982-07-28 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
GR78245B (enExample) * 1980-09-12 1984-09-26 Ciba Geigy Ag
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
JPS5823698A (ja) * 1981-07-17 1983-02-12 グラクソ・グル−プ・リミテツド セフアロスポリン化合物
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
GB8509087D0 (en) * 1985-04-09 1985-05-15 Fujisawa Pharmaceutical Co Cephem compounds
JPH085897B2 (ja) * 1986-11-06 1996-01-24 エーザイ株式会社 ３−プロペニルセフェム誘導体
EP0536900A3 (en) * 1991-09-12 1993-04-21 KATAYAMA SEIYAKUSYO CO. Ltd. Process for preparing 1,2,4-thiadiazole derivatives
ZA939336B (en) * 1992-12-21 1994-08-25 Fujisawa Pharmaceutical Co New cephem compounds
JPH0741485A (ja) * 1993-07-30 1995-02-10 Katayama Seiyakushiyo:Kk セフェム誘導体およびそれを含有する抗菌剤
CN1922190A (zh) * 2004-03-05 2007-02-28 盐野义制药株式会社 3－吡啶甲基头胞化合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
JPS484487U (enExample) * 1971-06-15 1973-01-19
BE793037A (fr) * 1971-12-23 1973-06-20 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide 7-acylamino-3-substitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus
JPS551275B2 (enExample) * 1972-04-18 1980-01-12
JPS5525195B2 (enExample) * 1972-06-29 1980-07-04
JPS5613717B2 (enExample) * 1973-02-02 1981-03-30
JPS5297990A (en) * 1976-02-13 1977-08-17 Glaxo Lab Ltd Cephalospoline compounds
JPS52143289A (en) * 1976-05-24 1977-11-29 Meiji Seika Kaisha Ltd Production of 7-amino-cephem derivatives by filamentous fungi
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
CA1215969A (en) * 1979-10-12 1986-12-30 Tsutomu Teraji Cephem compounds and processes for preparation thereof
JP2638104B2 (ja) * 1988-07-29 1997-08-06 三田工業株式会社 画像形成方法
JPH0240679A (ja) * 1988-08-01 1990-02-09 Fuji Xerox Co Ltd トナー像定着装置用定着ローラの被覆層形成方法及び被覆層形成装置

Also Published As

Publication number Publication date
JPH01193271A (ja) 1989-08-03
EP0027599A2 (en) 1981-04-29
EP0027599A3 (en) 1981-07-15
JPH0240679B2 (enExample) 1990-09-12
HU185014B (en) 1984-11-28
EP0027599B1 (en) 1984-10-03
JPH01193273A (ja) 1989-08-03
JPS57112396A (en) 1982-07-13
DE3069364D1 (en) 1984-11-08
JPH01193272A (ja) 1989-08-03

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Legal Events

Date Code Title Description
MKEX Expiry