CA1186622A - Homogeneous immunoassay with labeled monoclonal anti- analyte - Google Patents
Homogeneous immunoassay with labeled monoclonal anti- analyteInfo
- Publication number
- CA1186622A CA1186622A CA000415983A CA415983A CA1186622A CA 1186622 A CA1186622 A CA 1186622A CA 000415983 A CA000415983 A CA 000415983A CA 415983 A CA415983 A CA 415983A CA 1186622 A CA1186622 A CA 1186622A
- Authority
- CA
- Canada
- Prior art keywords
- analyte
- labeled
- label
- enzyme
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- NLVFBUXFDBBNBW-PBSUHMDJSA-S tobramycin(5+) Chemical compound [NH3+][C@@H]1C[C@H](O)[C@@H](C[NH3+])O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H]([NH3+])[C@H](O)[C@@H](CO)O2)O)[C@H]([NH3+])C[C@@H]1[NH3+] NLVFBUXFDBBNBW-PBSUHMDJSA-S 0.000 description 1
- 229940035722 triiodothyronine Drugs 0.000 description 1
- 239000002753 trypsin inhibitor Substances 0.000 description 1
- HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 108010079570 uropepsin Proteins 0.000 description 1
- 229940102566 valproate Drugs 0.000 description 1
- 229960003726 vasopressin Drugs 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35961082A | 1982-03-18 | 1982-03-18 | |
| US359,610 | 1982-03-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1186622A true CA1186622A (en) | 1985-05-07 |
Family
ID=23414570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000415983A Expired CA1186622A (en) | 1982-03-18 | 1982-11-19 | Homogeneous immunoassay with labeled monoclonal anti- analyte |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0088974A3 (forum.php) |
| JP (1) | JPS58176550A (forum.php) |
| AU (1) | AU549033B2 (forum.php) |
| CA (1) | CA1186622A (forum.php) |
| DK (1) | DK124083A (forum.php) |
| ES (1) | ES8503855A1 (forum.php) |
| GR (1) | GR77159B (forum.php) |
| IL (1) | IL67289A (forum.php) |
| NO (1) | NO830712L (forum.php) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0119767B1 (en) * | 1983-03-11 | 1990-11-22 | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. | Method of measuring ligands |
| DE3485339D1 (de) * | 1983-11-18 | 1992-01-23 | Fujirebio Kk | Verfahren zur messung eines biologischen ligands. |
| JPS60233555A (ja) * | 1984-01-05 | 1985-11-20 | オ−ソ・ダイアグノステイツク・システムズ・インコ−ポレ−テツド | 螢光エネルギ−移動を使用する抗遺伝子型検定 |
| JPS60228421A (ja) * | 1984-04-27 | 1985-11-13 | Shionogi & Co Ltd | モノクロ−ナル抗ヒトＩｇＧ抗体およびその製造法 |
| DE3586787T2 (de) * | 1984-05-11 | 1993-06-03 | Biowhittaker Inc | Fluoreszenztest fuer igg4. |
| JPS6222064A (ja) * | 1985-07-23 | 1987-01-30 | Teijin Ltd | 第８因子凝固活性抗原の測定方法 |
| ES8606501A1 (es) * | 1985-07-31 | 1986-04-01 | Abello Alergia & Inmunologia | Un metodo para determinar la presencia de igg especifica en sueros humanos |
| JPH02213766A (ja) * | 1989-02-15 | 1990-08-24 | Mochida Pharmaceut Co Ltd | 免疫測定用試薬および免疫測定器具 |
| GB8927503D0 (en) * | 1989-12-04 | 1990-02-07 | Kronem Systems Inc | Enzyme-amplified lanthanide chelate luminescence |
| JP2786336B2 (ja) * | 1991-03-04 | 1998-08-13 | 富士写真フイルム株式会社 | 免疫分析要素および免疫分析方法 |
| US5447846A (en) * | 1992-07-17 | 1995-09-05 | Fuji Photo Film C., Ltd. | Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte |
| WO1999013332A1 (en) | 1997-09-05 | 1999-03-18 | Matsushita Electric Industrial Co., Ltd. | Fluorescence polarization method |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE792798A (fr) * | 1971-12-16 | 1973-06-15 | Radiochemical Centre Ltd | Procede et reactifs destines notamment a des titrages radio-immunologiques |
| US3935074A (en) * | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| IN142734B (forum.php) * | 1975-04-28 | 1977-08-20 | Miles Lab | |
| IT1105734B (it) * | 1977-07-14 | 1985-11-04 | Syva Co | Prova di legame di competizione di antienzima omogeneo |
| DE3177290T2 (de) * | 1980-04-09 | 1993-04-15 | British Tech Group | Monoklonale antikoerper gegen hepatitis-b-virus. |
| CH642458A5 (en) * | 1980-04-25 | 1984-04-13 | Hoffmann La Roche | Immunological method |
| IL64574A (en) * | 1981-04-27 | 1986-01-31 | Syva Co | Method for determining the presence of an analyte by determination of the amount of fluorescence in competitive protein binding assays |
| GB2102946B (en) * | 1981-06-30 | 1984-11-28 | Wellcome Found | Enzyme immunoassay |
-
1982
- 1982-11-17 IL IL67289A patent/IL67289A/xx unknown
- 1982-11-19 CA CA000415983A patent/CA1186622A/en not_active Expired
- 1982-11-22 AU AU90768/82A patent/AU549033B2/en not_active Ceased
-
1983
- 1983-03-02 NO NO830712A patent/NO830712L/no unknown
- 1983-03-07 EP EP83102200A patent/EP0088974A3/en not_active Withdrawn
- 1983-03-16 GR GR70807A patent/GR77159B/el unknown
- 1983-03-17 DK DK124083A patent/DK124083A/da not_active Application Discontinuation
- 1983-03-17 JP JP58043292A patent/JPS58176550A/ja active Pending
- 1983-03-18 ES ES520777A patent/ES8503855A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58176550A (ja) | 1983-10-17 |
| NO830712L (no) | 1983-09-19 |
| EP0088974A2 (en) | 1983-09-21 |
| GR77159B (forum.php) | 1984-09-07 |
| EP0088974A3 (en) | 1986-05-28 |
| ES520777A0 (es) | 1985-03-16 |
| ES8503855A1 (es) | 1985-03-16 |
| AU9076882A (en) | 1983-09-22 |
| DK124083A (da) | 1983-09-19 |
| AU549033B2 (en) | 1986-01-09 |
| DK124083D0 (da) | 1983-03-17 |
| IL67289A0 (en) | 1983-03-31 |
| IL67289A (en) | 1985-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEC | Expiry (correction) | ||
| MKEX | Expiry | ||
| MKEX | Expiry |
Effective date: 20021119 |