CA1183853A - (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)- keton and its acid salts, use thereof in therapeutics and method for preparing same - Google Patents

(2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)- keton and its acid salts, use thereof in therapeutics and method for preparing same

Info

Publication number
CA1183853A
CA1183853A CA000400489A CA400489A CA1183853A CA 1183853 A CA1183853 A CA 1183853A CA 000400489 A CA000400489 A CA 000400489A CA 400489 A CA400489 A CA 400489A CA 1183853 A CA1183853 A CA 1183853A
Authority
CA
Canada
Prior art keywords
dimethoxy
ketone
hydroxyphenyl
piperidinopropyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000400489A
Other languages
English (en)
French (fr)
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of CA1183853A publication Critical patent/CA1183853A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000400489A 1981-04-15 1982-04-05 (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)- keton and its acid salts, use thereof in therapeutics and method for preparing same Expired CA1183853A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8107597 1981-04-15
FR8107597A FR2504136A1 (fr) 1981-04-15 1981-04-15 (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation

Publications (1)

Publication Number Publication Date
CA1183853A true CA1183853A (en) 1985-03-12

Family

ID=9257449

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000400489A Expired CA1183853A (en) 1981-04-15 1982-04-05 (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)- keton and its acid salts, use thereof in therapeutics and method for preparing same

Country Status (10)

Country Link
EP (1) EP0063075B1 (enrdf_load_stackoverflow)
JP (1) JPS57181073A (enrdf_load_stackoverflow)
AT (1) ATE8258T1 (enrdf_load_stackoverflow)
CA (1) CA1183853A (enrdf_load_stackoverflow)
DE (1) DE3260320D1 (enrdf_load_stackoverflow)
DK (1) DK156002C (enrdf_load_stackoverflow)
ES (1) ES8304105A1 (enrdf_load_stackoverflow)
FR (1) FR2504136A1 (enrdf_load_stackoverflow)
GR (1) GR75918B (enrdf_load_stackoverflow)
IE (1) IE52871B1 (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755522A (en) * 1986-04-28 1988-07-05 Laboratoire L. Lafon Derivatives of N-[3-(2,4,6-trimethoxybenzoyl)propyl]piperidine, and their use in therapeutics

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534912B1 (fr) * 1982-10-26 1985-06-28 Lafon Labor Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation
JP2569940Y2 (ja) * 1992-02-14 1998-04-28 株式会社ヨシコー 摩擦クラッチ
CZ289752B6 (cs) * 1993-05-26 2002-03-13 Syntex (U.S.A.) Inc. 1-Fenylalkanonové ligandy 5-HT4 receptoru, farmaceutický prostředek, který je obsahuje, způsob jejich přípravy a pouľití

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092133B1 (enrdf_load_stackoverflow) * 1970-05-06 1974-03-22 Orsymonde
FR2134218A1 (en) * 1971-04-27 1972-12-08 Penciolelli Madeleine Phloroglucinol aminoketones - vasodilators and antispasmodics
FR2404003A1 (fr) * 1977-09-26 1979-04-20 Lafon Labor Nouveaux derives de phloroglucinol, leur procede de preparation et leur application en therapeutique
GB2004883B (en) * 1977-09-26 1982-03-17 Lafon Labor Phloroglucinol derivatives their method of preparation and their use as pharmaceuticals

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755522A (en) * 1986-04-28 1988-07-05 Laboratoire L. Lafon Derivatives of N-[3-(2,4,6-trimethoxybenzoyl)propyl]piperidine, and their use in therapeutics

Also Published As

Publication number Publication date
DE3260320D1 (en) 1984-08-09
EP0063075B1 (fr) 1984-07-04
ES511431A0 (es) 1983-02-16
DK156002C (da) 1989-11-06
JPS57181073A (en) 1982-11-08
DK156002B (da) 1989-06-12
ATE8258T1 (de) 1984-07-15
JPH039112B2 (enrdf_load_stackoverflow) 1991-02-07
ES8304105A1 (es) 1983-02-16
IE820742L (en) 1982-10-15
EP0063075A1 (fr) 1982-10-20
FR2504136A1 (fr) 1982-10-22
GR75918B (enrdf_load_stackoverflow) 1984-08-02
FR2504136B1 (enrdf_load_stackoverflow) 1984-02-10
IE52871B1 (en) 1988-03-30
DK167782A (da) 1982-10-16

Similar Documents

Publication Publication Date Title
EP0159566B1 (en) Novel piperazine derivatives, processes for production thereof, and pharmaceutical compositions comprising said compounds as active ingredient
CH421078A (de) Verfahren zur Herstellung von Aminoacetylenverbindungen
IE48368B1 (en) Imidazole derivatives
CA1183853A (en) (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)- keton and its acid salts, use thereof in therapeutics and method for preparing same
EP0097340B1 (en) Piperazine derivatives, a process for preparing them and pharmaceutical compositions
CA1220225A (en) Diethyl-amino-alkoxy-benzhydrol derivatives, process for their preparation and pharmaceutical compositions containing them
JPH0316952B2 (enrdf_load_stackoverflow)
DE2819896A1 (de) Chromenderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
CA1216293A (en) PIPERIDINOPROPOXY-SUBSTITUTED .alpha.-ETHYL-BENZHYDROLS AND A PROCESS FOR THE PREPARATION THEREOF
US5175184A (en) Benzothiophene derivatives and antihyperuricemia thereof
US4206217A (en) 3-[4-(1,3-Diazacycloalken-2-yl)-phenyl]-1,2-benzisothiazoles, their manufacture, and drugs containing these compounds
US4568765A (en) Isoprenylamine derivatives
CA1212944A (en) Phenyl-(3-aminopropyl)-ketone derivatives
US5118682A (en) P-hydroxy phenone derivatives and the use thereof
Cain et al. Dihydroergot Relatives: Quinolinecarboxamides And Esters
EP0110747B1 (fr) Dérivés de (2,4,6-triméthoxyphényl-(3-pipéridinopropyl)-cétone, utilisation en thérapeutique et procédé de préparation
CA1293731C (en) Derivatives of n-¬3-(2,4,6-trimethoxybenzoyl) propyl| piperidine, their preparation processes and their use in therapeutics
CA1085847A (en) Piperazine derivatives, a process for their preparation and their applications
IE54987B1 (en) Benzhydrylsulfinylethylamine derivatives
US5274000A (en) Benzofuran and benzothiophene derivatives, anti-hyperuricemia agents
KR20010020378A (ko) 벤조티오펜의 제조 방법
HU178272B (en) Process for preparing new piperazino-methane-imino derivatives
FI78913C (fi) Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara 1-(aminoalkoxifenyl)-1-fenylpropanoler.
IL47060A (en) Quaternary ammonium salts of n-dialkylaminoalkyl-n-(2-indanyl)anilines
US4304929A (en) Process for preparing 4-(n-hexadecylamino)-benzoic acid

Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry