CA1170259A - Substituted quinazolines - Google Patents

Substituted quinazolines

Info

Publication number
CA1170259A
CA1170259A CA000397528A CA397528A CA1170259A CA 1170259 A CA1170259 A CA 1170259A CA 000397528 A CA000397528 A CA 000397528A CA 397528 A CA397528 A CA 397528A CA 1170259 A CA1170259 A CA 1170259A
Authority
CA
Canada
Prior art keywords
formula
hydrogen
compound
amino
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000397528A
Other languages
English (en)
French (fr)
Inventor
Hans-Jurgen E. Hess
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd Great Britain
Original Assignee
Pfizer Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd Great Britain filed Critical Pfizer Ltd Great Britain
Application granted granted Critical
Publication of CA1170259A publication Critical patent/CA1170259A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9453—Cardioregulators, e.g. antihypotensives, antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA000397528A 1981-03-05 1982-03-03 Substituted quinazolines Expired CA1170259A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24074581A 1981-03-05 1981-03-05
US240,745 1981-03-05

Publications (1)

Publication Number Publication Date
CA1170259A true CA1170259A (en) 1984-07-03

Family

ID=22907776

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000397528A Expired CA1170259A (en) 1981-03-05 1982-03-03 Substituted quinazolines

Country Status (8)

Country Link
EP (1) EP0060081B1 (https=)
JP (1) JPS57158763A (https=)
AU (1) AU528068B2 (https=)
CA (1) CA1170259A (https=)
DE (1) DE3264718D1 (https=)
DK (1) DK94382A (https=)
GR (1) GR75878B (https=)
IE (1) IE52578B1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS236097B1 (en) * 1983-06-01 1985-05-15 Jan Koenig Acylderivatives of 2-piperazinochinazoline and method of their preparation
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
JPH0647540B2 (ja) * 1985-07-16 1994-06-22 エーザイ株式会社 虚血性心疾患・不整脈治療・予防剤
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
FR2601141A1 (fr) * 1986-07-02 1988-01-08 Centre Nat Rech Scient Produit de couplage a base d'haptene, utile notamment comme substance immunogene, anticorps correspondants et applications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189484A (en) * 1977-11-08 1980-02-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Antihypertensive quinazoline derivatives
DE2901218A1 (de) * 1979-01-13 1980-07-17 Byk Gulden Lomberg Chem Fab Ung von theophyllin

Also Published As

Publication number Publication date
AU8111582A (en) 1982-11-04
GR75878B (https=) 1984-08-02
AU528068B2 (en) 1983-04-14
IE52578B1 (en) 1987-12-23
JPS621947B2 (https=) 1987-01-16
EP0060081A2 (en) 1982-09-15
JPS57158763A (en) 1982-09-30
EP0060081A3 (en) 1982-12-22
EP0060081B1 (en) 1985-07-17
DE3264718D1 (en) 1985-08-22
DK94382A (da) 1982-09-06
IE820486L (en) 1982-09-05

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Legal Events

Date Code Title Description
MKEX Expiry