CA1161271A - Method and apparatus for measuring mean cell volume of red blood cells - Google Patents

Method and apparatus for measuring mean cell volume of red blood cells

Info

Publication number
CA1161271A
CA1161271A CA000375813A CA375813A CA1161271A CA 1161271 A CA1161271 A CA 1161271A CA 000375813 A CA000375813 A CA 000375813A CA 375813 A CA375813 A CA 375813A CA 1161271 A CA1161271 A CA 1161271A
Authority
CA
Canada
Prior art keywords
cell
cells
logic
red blood
mean cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000375813A
Other languages
English (en)
French (fr)
Inventor
James W. Bacus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rush Presbyterian St Lukes Medical Center
Original Assignee
Rush Presbyterian St Lukes Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rush Presbyterian St Lukes Medical Center filed Critical Rush Presbyterian St Lukes Medical Center
Priority to CA000440323A priority Critical patent/CA1180811A/en
Application granted granted Critical
Publication of CA1161271A publication Critical patent/CA1161271A/en
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • G06T7/62Analysis of geometric attributes of area, perimeter, diameter or volume
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • G06T7/64Analysis of geometric attributes of convexity or concavity
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00Arrangements for image or video recognition or understanding
    • G06V10/40Extraction of image or video features
    • G06V10/42Global feature extraction by analysis of the whole pattern, e.g. using frequency domain transformations or autocorrelation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698Matching; Classification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Geometry (AREA)
  • Multimedia (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
CA000375813A 1980-04-21 1981-04-21 Method and apparatus for measuring mean cell volume of red blood cells Expired CA1161271A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000440323A CA1180811A (en) 1980-04-21 1983-11-02 Method and apparatus for measuring mean cell volume of red blood cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/142,124 US4453266A (en) 1980-04-21 1980-04-21 Method and apparatus for measuring mean cell volume of red blood cells
US142,124 1980-04-21

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000440323A Division CA1180811A (en) 1980-04-21 1983-11-02 Method and apparatus for measuring mean cell volume of red blood cells

Publications (1)

Publication Number Publication Date
CA1161271A true CA1161271A (en) 1984-01-31

Family

ID=22498630

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000375813A Expired CA1161271A (en) 1980-04-21 1981-04-21 Method and apparatus for measuring mean cell volume of red blood cells

Country Status (5)

Country Link
US (1) US4453266A (enExample)
EP (1) EP0051633A1 (enExample)
JP (1) JPH0475463B2 (enExample)
CA (1) CA1161271A (enExample)
WO (1) WO1981003080A1 (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596464A (en) * 1983-10-14 1986-06-24 Ortho Diagnostic Systems, Inc. Screening method for red cell abnormality
US4593406A (en) * 1984-01-16 1986-06-03 The United States Of America As Represented By The United States Department Of Energy Automatic image acquisition processor and method
US4998284A (en) * 1987-11-17 1991-03-05 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
US4741043B1 (en) * 1985-11-04 1994-08-09 Cell Analysis Systems Inc Method of and apparatus for image analyses of biological specimens
US5109429A (en) * 1985-11-04 1992-04-28 Cell Analysis Systems,Inc. Apparatus and method for analyses of biological specimens
US5086476A (en) * 1985-11-04 1992-02-04 Cell Analysis Systems, Inc. Method and apparatus for determining a proliferation index of a cell sample
US5016283A (en) * 1985-11-04 1991-05-14 Cell Analysis Systems, Inc. Methods and apparatus for immunoploidy analysis
US5134662A (en) * 1985-11-04 1992-07-28 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
US4794450A (en) * 1986-08-29 1988-12-27 Fujirebio Kabushiki Kaisha Method and apparatus for judging agglutination pattern
DE3718066A1 (de) * 1987-05-29 1988-12-08 Zeiss Carl Fa Verfahren zur mikroinjektion in zellen bzw. zum absaugen aus einzelnen zellen oder ganzer zellen aus zellkulturen
US4907156A (en) * 1987-06-30 1990-03-06 University Of Chicago Method and system for enhancement and detection of abnormal anatomic regions in a digital image
US5121436A (en) * 1987-08-14 1992-06-09 International Remote Imaging Systems, Inc. Method and apparatus for generating a plurality of parameters of an object in a field of view
JP2686274B2 (ja) * 1988-03-24 1997-12-08 東亜医用電子株式会社 細胞画像処理方法および装置
US4918739A (en) * 1988-08-12 1990-04-17 Maraven, S.A. Process and system for digital analysis of images applied to stratigraphic data
US5061632A (en) * 1989-01-31 1991-10-29 Board Of Regents, The University Of Texas System Capillary tube hemoglobinometer and oximeter
US6262798B1 (en) * 1992-09-29 2001-07-17 Board Of Regents, The University Of Texas System Method and apparatus for direct spectrophotometric measurements in unaltered whole blood
JP2955873B2 (ja) * 1989-08-10 1999-10-04 富士写真フイルム株式会社 画像処理装置
US5212637A (en) * 1989-11-22 1993-05-18 Stereometrix Corporation Method of investigating mammograms for masses and calcifications, and apparatus for practicing such method
JP2874008B2 (ja) * 1990-05-18 1999-03-24 スズキ株式会社 粒子凝集パターン判定装置
GB2254414A (en) * 1991-03-21 1992-10-07 Univ London Volume measurement of microbial organisms.
US5218645A (en) * 1991-03-29 1993-06-08 Cell Analysis Systems, Inc. Method and apparatus for separating cell objects for analysis
US6058209A (en) * 1991-09-27 2000-05-02 E. I. Du Pont De Nemours And Company Method for resolving redundant identifications of an object
US5982944A (en) * 1991-09-27 1999-11-09 E. I. Du Pont De Nemours And Company Adaptive vision system using dual thresholding
US5375177A (en) * 1991-09-27 1994-12-20 E. I. Du Pont De Nemours And Company Method of identifying and characterizing a valid object by color
US5481620A (en) * 1991-09-27 1996-01-02 E. I. Du Pont De Nemours And Company Adaptive vision system
US5371810A (en) * 1991-09-27 1994-12-06 E. I. Du Pont De Nemours And Company Method of determining the interior points of an object in a background
US5579409A (en) * 1991-09-27 1996-11-26 E. I. Du Pont De Nemours And Company Methods for determining the exterior points of an object in a background
WO1993018182A1 (en) * 1992-03-09 1993-09-16 Difco Laboratories Diagnostic microbiological testing apparatus and method
US6026174A (en) * 1992-10-14 2000-02-15 Accumed International, Inc. System and method for automatically detecting malignant cells and cells having malignancy-associated changes
US5889881A (en) * 1992-10-14 1999-03-30 Oncometrics Imaging Corp. Method and apparatus for automatically detecting malignancy-associated changes
US5754688A (en) * 1993-06-04 1998-05-19 Eli Lilly And Company Method and apparatus for stereologic analysis of two-dimensional images
US5598842A (en) * 1993-09-03 1997-02-04 Toa Medical Electronics Co., Ltd. Non-invasive blood analyzer and method using the same
US5791345A (en) * 1993-09-03 1998-08-11 Toa Medical Electronics Co., Ltd. Non-invasive blood analyzer
JP3364323B2 (ja) * 1994-05-17 2003-01-08 謙 石原 非侵襲血液分析装置
US5848177A (en) * 1994-12-29 1998-12-08 Board Of Trustees Operating Michigan State University Method and system for detection of biological materials using fractal dimensions
AP931A (en) * 1995-10-23 2001-02-02 Cytometrics Inc Method and apparatus for reflected imaging analysis.
US6970587B1 (en) 1997-08-28 2005-11-29 Icad, Inc. Use of computer-aided detection system outputs in clinical practice
US6137898A (en) * 1997-08-28 2000-10-24 Qualia Computing, Inc. Gabor filtering for improved microcalcification detection in digital mammograms
US5999639A (en) 1997-09-04 1999-12-07 Qualia Computing, Inc. Method and system for automated detection of clustered microcalcifications from digital mammograms
US7308126B2 (en) * 1997-08-28 2007-12-11 Icad, Inc. Use of computer-aided detection system outputs in clinical practice
US6801645B1 (en) 1999-06-23 2004-10-05 Icad, Inc. Computer aided detection of masses and clustered microcalcifications with single and multiple input image context classification strategies
JP2003263466A (ja) * 2002-03-08 2003-09-19 Umc Japan 電子系cad装置及びそのレイアウトデータ作製方法、コンピュータプログラム
US7274809B2 (en) * 2002-08-29 2007-09-25 Perceptronix Medical, Inc. And British Columbia Cancer Agency Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer
US6981083B2 (en) * 2002-12-05 2005-12-27 International Business Machines Corporation Processor virtualization mechanism via an enhanced restoration of hard architected states
US20040202357A1 (en) 2003-04-11 2004-10-14 Perz Cynthia B. Silhouette image acquisition
JP4328586B2 (ja) * 2003-09-02 2009-09-09 キヤノン株式会社 放射線画像連結処理方法、放射線画像連結処理装置、コンピュータプログラム及びコンピュータ読み取り可能な記録媒体
EP2244086B1 (de) * 2006-04-08 2021-06-09 Roche Diabetes Care GmbH Analyse optischer Daten mit Hilfe von Histogrammen
US7903241B2 (en) * 2008-03-21 2011-03-08 Abbott Point Of Care, Inc. Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
CA2720077C (en) * 2008-04-09 2014-08-05 Abbott Point Of Care, Inc. Method for measuring the area of a sample disposed within an analysis chamber
WO2012142496A1 (en) 2011-04-15 2012-10-18 Constitution Medical, Inc. Measuring volume and constituents of cells
US9459196B2 (en) 2011-07-22 2016-10-04 Roche Diagnostics Hematology, Inc. Blood analyzer calibration and assessment
CN102819765B (zh) * 2012-02-28 2016-01-20 浙江工业大学 一种基于计算机视觉的牛奶体细胞计数方法
EP3955042B1 (en) 2013-08-26 2024-08-21 S.D. Sight Diagnostics Ltd. Digital microscopy systems, methods and computer program products
CN104655546B (zh) * 2015-03-12 2017-07-07 重庆大学 一种基于移动设备的牛奶体细胞计数方法及系统
AU2016322966B2 (en) 2015-09-17 2021-10-14 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
WO2017168411A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Image processing device for identifying blood parasites
CN109564209B (zh) 2016-05-11 2022-05-31 思迪赛特诊断有限公司 对样品实施的光学测量
US11307196B2 (en) 2016-05-11 2022-04-19 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
US11189027B2 (en) * 2017-05-15 2021-11-30 Sigtuple Technologies Private Limited Method and system for determining area to be scanned in peripheral blood smear for analysis
EP3710810B1 (en) 2017-11-14 2023-09-06 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
US11187644B2 (en) * 2018-04-09 2021-11-30 Sigtuple Technologies Private Limited Method and system for determining total count of red blood cells in peripheral blood smear
AU2020400401A1 (en) 2019-12-12 2022-06-02 S.D. Sight Diagnostics Ltd Analyzing an analyte disposed within a medium
JP7677972B2 (ja) 2019-12-12 2025-05-15 エス.ディー.サイト ダイアグノスティックス リミテッド カラー血液スミア画像の人工的な生成

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2656508A (en) * 1949-08-27 1953-10-20 Wallace H Coulter Means for counting particles suspended in a fluid
US3259842A (en) * 1959-08-19 1966-07-05 Coulter Electronics Particle analyzing device
US3851156A (en) * 1972-09-05 1974-11-26 Green James E Analysis method and apparatus utilizing color algebra and image processing techniques
US3944797A (en) * 1974-08-06 1976-03-16 Coulter Electronics, Inc. Method and apparatus for determining the correct percentiles of the size distribution of a particulate system
US4052596A (en) * 1974-12-23 1977-10-04 Hycel, Inc. Automatic hematology analyzer
US3982183A (en) * 1975-02-20 1976-09-21 Coulter Electronics, Inc. Particle sizing apparatus
GB1538225A (en) * 1975-02-28 1979-01-10 Nat Res Dev Methods and apparatus for analysing frequency distributions
US4063309A (en) * 1976-09-16 1977-12-13 Hycel, Inc. Mean corpuscular volume measuring apparatus and method
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells
GB1603643A (en) * 1978-03-06 1981-11-25 Coulter Electronics Detection of blood disorders

Also Published As

Publication number Publication date
US4453266A (en) 1984-06-05
JPS57500625A (enExample) 1982-04-08
WO1981003080A1 (en) 1981-10-29
JPH0475463B2 (enExample) 1992-11-30
EP0051633A1 (en) 1982-05-19

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