CA1157373A - Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s) - Google Patents

Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s)

Info

Publication number
CA1157373A
CA1157373A CA000343088A CA343088A CA1157373A CA 1157373 A CA1157373 A CA 1157373A CA 000343088 A CA000343088 A CA 000343088A CA 343088 A CA343088 A CA 343088A CA 1157373 A CA1157373 A CA 1157373A
Authority
CA
Canada
Prior art keywords
antibodies
nucleoli
human
cells
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000343088A
Other languages
English (en)
French (fr)
Inventor
Harris Busch
Rosek Busch
Ferenc Gyorkey
Phyllis Gyorkey
Frances M. Davis
Karel Smetana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Original Assignee
Baylor College of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine
Priority to CA000343088A priority Critical patent/CA1157373A/en
Priority to NZ195756A priority patent/NZ195756A/xx
Priority to IE2533/80A priority patent/IE50760B1/en
Priority to AU65070/80A priority patent/AU535024B2/en
Priority to IL61641A priority patent/IL61641A/xx
Priority to ZA00807754A priority patent/ZA807754B/xx
Priority to PH24978A priority patent/PH18765A/en
Priority to DE19803047654 priority patent/DE3047654A1/de
Priority to LU83015A priority patent/LU83015A1/fr
Priority to NO803910A priority patent/NO803910L/no
Priority to AR283753A priority patent/AR232046A1/es
Priority to JP18948880A priority patent/JPS56101553A/ja
Priority to DK554980A priority patent/DK554980A/da
Priority to CH9652/80A priority patent/CH659328A5/de
Priority to KR1019800005026A priority patent/KR850001770B1/ko
Priority to BE0/203378A priority patent/BE886935A/fr
Priority to NL8007128A priority patent/NL8007128A/nl
Priority to PT72301A priority patent/PT72301B/pt
Priority to GB8041638A priority patent/GB2067286B/en
Priority to FR8100014A priority patent/FR2484650B1/fr
Priority to FI810007A priority patent/FI810007L/fi
Priority to SE8100011A priority patent/SE450665B/sv
Priority to ES498305A priority patent/ES8206855A1/es
Priority to AT0001081A priority patent/AT373397B/de
Priority to GR63789A priority patent/GR72850B/el
Priority to OA57289A priority patent/OA06713A/xx
Priority to IT67001/81A priority patent/IT1172216B/it
Priority to ES509239A priority patent/ES8307377A1/es
Priority to AT426382A priority patent/ATA426382A/de
Priority to PH28547A priority patent/PH18637A/en
Priority to PH28549A priority patent/PH18636A/en
Priority to PH28550A priority patent/PH18129A/en
Priority to PH28548A priority patent/PH18624A/en
Priority to CA000424445A priority patent/CA1172165A/en
Application granted granted Critical
Publication of CA1157373A publication Critical patent/CA1157373A/en
Priority to NO850005A priority patent/NO850005L/no
Priority to NO864091A priority patent/NO864091D0/no
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
CA000343088A 1980-01-04 1980-01-04 Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s) Expired CA1157373A (en)

Priority Applications (36)

Application Number Priority Date Filing Date Title
CA000343088A CA1157373A (en) 1980-01-04 1980-01-04 Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s)
NZ195756A NZ195756A (en) 1980-01-04 1980-12-04 Human cancer cell-associated nucleolar antigens and antibodies thereto;immunological detection of cancer
IE2533/80A IE50760B1 (en) 1980-01-04 1980-12-04 Detection of human cancer cells with antibodies to human cancer nucleolar antigens
AU65070/80A AU535024B2 (en) 1980-01-04 1980-12-04 Detecting cancer with antibodies
IL61641A IL61641A (en) 1980-01-04 1980-12-05 Human cancer cell associated antigens,their preparation and purification,a diagnostic kit comprising antibodies thereto and its use for immunological detection of cancer
ZA00807754A ZA807754B (en) 1980-01-04 1980-12-10 Detection of human cancer cells with antibodies to human cancer nucleolar antigens
PH24978A PH18765A (en) 1980-01-04 1980-12-15 Diagnostic kits comprising specific antibodies and antisera
DE19803047654 DE3047654A1 (de) 1980-01-04 1980-12-17 Verfahren zum immunologischen nachweis von krebs in menschlichen gewebeschnitten, abstrichen und abblaetternden zytologischen praeparaten sowie dabei verwendete reagentien und diagnosemittel
LU83015A LU83015A1 (fr) 1980-01-04 1980-12-18 Procede de detection de cellules cancereuses par des anticorps et procede de preparation de ceux-ci
NO803910A NO803910L (no) 1980-01-04 1980-12-22 Fremgangsmaate for immunologisk paavisning av kreft i vev hos mennesker.
AR283753A AR232046A1 (es) 1980-01-04 1980-12-22 Procedimiento para obtener antigenos nucleolares purificados de celulas cancerosas y los antigenos purificados asi obtenidos
JP18948880A JPS56101553A (en) 1980-01-04 1980-12-27 Detection of human cancerous cell with antibody of human cancerous nucleolus antigen
DK554980A DK554980A (da) 1980-01-04 1980-12-29 Paavisning af humane cancerceller med antistoffer til humane cancernukleolare antigener
KR1019800005026A KR850001770B1 (ko) 1980-01-04 1980-12-30 인체 암 항원에 대한 특이항체의 제조방법
CH9652/80A CH659328A5 (de) 1980-01-04 1980-12-30 Verfahren zur isolierung von nukleolaren antigenen aus humanen krebszellen.
GB8041638A GB2067286B (en) 1980-01-04 1980-12-31 Detection of human cancer cells with antibodies to human cancer cell nucleolar antigen(s)
NL8007128A NL8007128A (nl) 1980-01-04 1980-12-31 Detectie van menselijke kankercellen met antilichamen voor antigenen uit de nucleoli van menselijke kankercellen.
PT72301A PT72301B (en) 1980-01-04 1980-12-31 Process for the detection of human cancer cells with antibodies to human cancer nucleolar antigens
BE0/203378A BE886935A (fr) 1980-01-04 1980-12-31 Procede de detection de cellules cancereuses par des anti-corps et procede de preparation de ceux-ci
FI810007A FI810007L (fi) 1980-01-04 1981-01-02 Bestaemning av maenskliga cancerceller med antikroppar mot nucleoaera antigener av maenskliga cancerceller
SE8100011A SE450665B (sv) 1980-01-04 1981-01-02 Nukleolera antigener fran cancerceller, framstellning av motsvarande antikroppar och reagenslosning innehallande merkta antikroppar
ES498305A ES8206855A1 (es) 1980-01-04 1981-01-02 Un procedimiento para la preparacion de anticuerpos con especialidad frente a antigenos encontrados en los nucleos y nu-cleolos de las celulas humanas cancerosas.
FR8100014A FR2484650B1 (fr) 1980-01-04 1981-01-02 Procede de detection des cellules cancereuses humaines avec des anticorps contre les antigenes nucleolaires des cancers humains
OA57289A OA06713A (fr) 1980-01-04 1981-01-05 Méthode et réactifs pour la détection immunologique du cancer.
GR63789A GR72850B (ko) 1980-01-04 1981-01-05
AT0001081A AT373397B (de) 1980-01-04 1981-01-05 Verfahren zum immunologischen nachweis von krebs in menschlichen geweben
IT67001/81A IT1172216B (it) 1980-01-04 1981-01-05 Procentimento e mezzi per la rivelazione immunologica di cellule cance rose nei campioni di tessuti umani
ES509239A ES8307377A1 (es) 1980-01-04 1982-02-01 Un procedimiento para detectar la localizacion del producto de reaccion antigeno-anticuerpoen la celulas malignas.
AT426382A ATA426382A (de) 1980-01-04 1982-11-23 Verfahren zur erzeugung von antikoerpern bzw. antisera gegen antigene in menschlichen krebszellen zum immunologischen nachweis von krebs
PH28547A PH18637A (en) 1980-01-04 1983-02-21 Detection of human cancer cells with antibodies to human cancer nucleolar antigens
PH28549A PH18636A (en) 1980-01-04 1983-02-21 Method of purifying nucleolar antigens
PH28550A PH18129A (en) 1980-01-04 1983-02-21 Detection of human cancer cella with antibodies to human cancer nucleolar antigens
PH28548A PH18624A (en) 1980-01-04 1983-02-21 Detection of human cancer cells with antibodies to human cancer nucleolar antigens
CA000424445A CA1172165A (en) 1980-01-04 1983-03-24 Detection of human cancer cells with antibodies to human cancer nucleolar antegen(s)
NO850005A NO850005L (no) 1980-01-04 1985-01-02 Nukleaert preparat, fremgangsmaate for rensing av nukleolaere antigener samt fremgangsmaate for rensing av antistoffer
NO864091A NO864091D0 (no) 1980-01-04 1986-10-14 Antigener fra isolerte nukleoli og nukleaere ekstrakter samt diagnostisk utstyr for bruk ved immunologisk paavisning av krefter.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000343088A CA1157373A (en) 1980-01-04 1980-01-04 Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000424445A Division CA1172165A (en) 1980-01-04 1983-03-24 Detection of human cancer cells with antibodies to human cancer nucleolar antegen(s)

Publications (1)

Publication Number Publication Date
CA1157373A true CA1157373A (en) 1983-11-22

Family

ID=4115973

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000343088A Expired CA1157373A (en) 1980-01-04 1980-01-04 Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s)

Country Status (27)

Country Link
JP (1) JPS56101553A (ko)
KR (1) KR850001770B1 (ko)
AR (1) AR232046A1 (ko)
AT (1) AT373397B (ko)
AU (1) AU535024B2 (ko)
BE (1) BE886935A (ko)
CA (1) CA1157373A (ko)
CH (1) CH659328A5 (ko)
DE (1) DE3047654A1 (ko)
DK (1) DK554980A (ko)
ES (2) ES8206855A1 (ko)
FI (1) FI810007L (ko)
FR (1) FR2484650B1 (ko)
GB (1) GB2067286B (ko)
GR (1) GR72850B (ko)
IE (1) IE50760B1 (ko)
IL (1) IL61641A (ko)
IT (1) IT1172216B (ko)
LU (1) LU83015A1 (ko)
NL (1) NL8007128A (ko)
NO (2) NO803910L (ko)
NZ (1) NZ195756A (ko)
OA (1) OA06713A (ko)
PH (5) PH18765A (ko)
PT (1) PT72301B (ko)
SE (1) SE450665B (ko)
ZA (1) ZA807754B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487830A (en) * 1982-05-14 1984-12-11 American Hoechst Corporation Enzyme/immunofluorescent assay for autoantibodies
JPS5990052A (ja) * 1982-11-16 1984-05-24 Katsu Taniguchi モノクロ−ナル特異抗体を用いたメラノ−マ診断薬
US4746539A (en) * 1983-11-23 1988-05-24 The Ohio State University Research Foundation Purification of cancer-associated protein and preparation of antibody thereto
US4871661A (en) * 1983-11-23 1989-10-03 The Ohio State University Research Foundation Process for testing the carcinogenicity of a material or the presence of cancer-inducing factors in an environment
EP0145373B1 (en) * 1983-11-23 1992-03-25 The Ohio State University Research Foundation Purification of cancer-associated protein and preparation of antibody thereto
US4645737A (en) * 1984-03-05 1987-02-24 American Hoechst Corporation Enzyme/immunofluorescent assay for anti-treponemal antibodies
US4607008A (en) * 1984-03-05 1986-08-19 American Hoechst Corporation Enzyme/immunofluorescent assay for anti-Epstein-Barr Virus antibodies
DE3485740D1 (de) * 1984-05-02 1992-06-25 Univ Research Corp Immunologisches testverfahren eines prokoagulierenden enzyms zum nachweis von krebs.
US4616658A (en) * 1985-02-27 1986-10-14 William Shell Non-radioactively labeled microspheres and use of same to measure blood flow
US4798719A (en) * 1986-09-11 1989-01-17 University Of Pittsburgh Method for selection of antigens suitable as in vivo targets for antibodies
US5019368A (en) * 1989-02-23 1991-05-28 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
US4861581A (en) * 1986-12-05 1989-08-29 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
CA2023030A1 (en) * 1990-07-13 1992-01-14 Robert R. Guerrero In vitro method and probe for detecting the presence of the ring shaped particle and malignancy in humans and animals

Also Published As

Publication number Publication date
CH659328A5 (de) 1987-01-15
ATA1081A (de) 1983-05-15
DK554980A (da) 1981-07-05
PH18765A (en) 1985-09-20
ES498305A0 (es) 1982-08-01
ES509239A0 (es) 1983-06-16
KR830003898A (ko) 1983-06-30
FI810007L (fi) 1981-07-05
GB2067286B (en) 1984-01-04
OA06713A (fr) 1982-06-30
IE802533L (en) 1981-07-04
NZ195756A (en) 1983-11-18
DE3047654C2 (ko) 1990-12-20
NO850005L (no) 1981-07-06
IL61641A0 (en) 1981-01-30
GB2067286A (en) 1981-07-22
FR2484650A1 (fr) 1981-12-18
JPS56101553A (en) 1981-08-14
ES8307377A1 (es) 1983-06-16
PH18636A (en) 1985-08-23
PT72301A (en) 1981-01-01
PT72301B (en) 1981-11-10
AU6507080A (en) 1981-07-09
BE886935A (fr) 1981-04-16
PH18624A (en) 1985-08-21
IT1172216B (it) 1987-06-18
NL8007128A (nl) 1981-08-03
SE8100011L (sv) 1981-07-05
ES8206855A1 (es) 1982-08-01
IE50760B1 (en) 1986-07-09
LU83015A1 (fr) 1981-06-04
PH18129A (en) 1985-03-22
IT8167001A0 (it) 1981-01-05
IL61641A (en) 1984-03-30
ZA807754B (en) 1982-02-24
AU535024B2 (en) 1984-03-01
GR72850B (ko) 1983-12-07
KR850001770B1 (ko) 1985-12-18
AT373397B (de) 1984-01-10
PH18637A (en) 1985-08-23
NO803910L (no) 1981-07-06
AR232046A1 (es) 1985-04-30
FR2484650B1 (fr) 1985-06-21
SE450665B (sv) 1987-07-13
DE3047654A1 (de) 1981-09-10

Similar Documents

Publication Publication Date Title
Busch et al. A nucleolar antigen found in a broad range of human malignant tumor specimens
CA1157373A (en) Detection of human cancer cells with antibodies to human cancer nucleolar antigen(s)
Bhattacharya et al. Immunologic studies of human serous cystadenocarcinoma of ovary. Demonstration of tumor‐associated antigens
JPS63290965A (ja) Ca125卵巣癌抗原用腫瘍特異性アッセイ
JPH08275778A (ja) モノクローナル抗体生産性ハイブリドマ細胞系
US5866690A (en) Detection of malignant tumor cells
US4448890A (en) Detection of human cancer cells with antibodies to human cancer nucleolar antigens
Busch et al. Rabbit antibodies to nucleoli of Novikoff hepatoma and normal liver of the rat
US4486538A (en) Detection of malignant tumor cells
Biberfeld et al. Surface immunoglobulin light chain determinants on normal and PHA-stimulated human blood lymphocytes studied by immunofluorescence and electronmicroscopy
Hiramoto et al. Reactions of antisera prepared against HeLa cells and normal fetal liver cells with adult human tissues
CA1165685A (en) Purified prostatic tissue antigen
US4794077A (en) Detection of human cancer cells with anitbodies to human cancer nucleolar antigen p145
CA1172165A (en) Detection of human cancer cells with antibodies to human cancer nucleolar antegen(s)
Charney et al. Demonstration, purification, and partial characterization of abnormal (HSL) antigens in stable human cell lines
US4916055A (en) Detection of human cancer with a monoclonal antibody specific for antigen gp650
EP0007214A1 (en) Product for detecting the presence of cancerous or malignant tumor cells
US4840915A (en) Method for diagnosing malignant tumors
Sulitzeanu Antigenic components of rat connective tissue.
Aarli Localization and Properties of an Acid‐Solubl'e Muscle Antigen Reacting with Antibodies in Myasthenia Gravis Sera
Lerner et al. Cell-surface antigens from human breast tumor cells
US4976957A (en) Process for the production of recognins and their chemoreciprocals
BARNHART Immunologic techniques
Greenfield et al. Immunohistochemical and biochemical characterization of antisera raised to human tumor nucleoli
Janković et al. Localizing properties of anti-nervous tissue antibodies in rat cervical ganglion

Legal Events

Date Code Title Description
MKEX Expiry