CA1153383A - Dibenzoxepin derivatives and process for the preparation thereof - Google Patents

Dibenzoxepin derivatives and process for the preparation thereof

Info

Publication number
CA1153383A
CA1153383A CA000205427A CA205427A CA1153383A CA 1153383 A CA1153383 A CA 1153383A CA 000205427 A CA000205427 A CA 000205427A CA 205427 A CA205427 A CA 205427A CA 1153383 A CA1153383 A CA 1153383A
Authority
CA
Canada
Prior art keywords
group
compound
formula
oxepin
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000205427A
Other languages
English (en)
French (fr)
Inventor
Katsujiro Ueno
Shiro Kubo
Toshiyuki Yoshioka
Hiroaki Tagawa
Sadakatsu Shimada
Hiroshi Kojima
Wataru Tsukada
Masao Tsubokawa
Tohru Masukawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8333673A external-priority patent/JPS5516428B2/ja
Priority claimed from JP8374273A external-priority patent/JPS558979B2/ja
Priority claimed from JP8443473A external-priority patent/JPS5516429B2/ja
Priority claimed from JP1692774A external-priority patent/JPS50108281A/ja
Priority claimed from JP1692674A external-priority patent/JPS5724352B2/ja
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1153383A publication Critical patent/CA1153383A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12[b,e]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Health & Medical Sciences (AREA)
  • Pyrane Compounds (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
CA000205427A 1973-07-24 1974-07-23 Dibenzoxepin derivatives and process for the preparation thereof Expired CA1153383A (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP8333673A JPS5516428B2 (fi) 1973-07-24 1973-07-24
JP83336/1973 1973-07-24
JP83742/1973 1973-07-25
JP8374273A JPS558979B2 (fi) 1973-07-25 1973-07-25
JP8443473A JPS5516429B2 (fi) 1973-07-26 1973-07-26
JP84434/1973 1973-07-26
JP1692774A JPS50108281A (fi) 1974-02-12 1974-02-12
JP16927/1974 1974-02-12
JP16926/1974 1974-02-12
JP1692674A JPS5724352B2 (fi) 1974-02-12 1974-02-12

Publications (1)

Publication Number Publication Date
CA1153383A true CA1153383A (en) 1983-09-06

Family

ID=27519864

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000205427A Expired CA1153383A (en) 1973-07-24 1974-07-23 Dibenzoxepin derivatives and process for the preparation thereof

Country Status (11)

Country Link
AR (1) AR210725A1 (fi)
BE (1) BE818055A (fi)
CA (1) CA1153383A (fi)
CH (6) CH605898A5 (fi)
DE (1) DE2435613B2 (fi)
DK (1) DK396874A (fi)
FR (1) FR2245356B1 (fi)
GB (2) GB1476215A (fi)
NL (1) NL159381B (fi)
SE (2) SE7409577L (fi)
YU (5) YU204274A (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES444144A1 (es) * 1975-01-14 1977-08-16 Hoechst Ag Un procedimiento para la preparacion de un acido 6,11-dihi- dro-11-oxo-dibenz (b, e) oxepin-alcanoico.
DE2600768C2 (de) * 1975-02-04 1983-10-27 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung von 6,11-Dihydro-11-oxodibenz[b,e]-oxepin-alkansäuren
DE2629569A1 (de) * 1975-07-30 1977-03-31 Hoechst Ag 6,11-dihydro-11-oxodibenz eckige klammer auf b,e eckige klammer zu oxepin-alkansaeuren und deren ester sowie verfahren zu ihrer herstellung
US4082850A (en) 1976-04-16 1978-04-04 American Hoechst Corporation Method of treating dermal inflammations
JPS54122284A (en) * 1978-02-17 1979-09-21 Dainippon Pharmaceut Co Ltd Dibenzb,foxepin derivative
JPS56156273A (en) 1980-03-31 1981-12-02 Dainippon Pharmaceut Co Ltd Acetic derivative
DE3125374A1 (de) * 1981-06-27 1983-01-13 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von heteroaryl- und dibenzoxepinalkansaeuren
US4576960A (en) * 1981-12-23 1986-03-18 Hoechst Roussel Pharmaceuticals Incorporated 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives
US4515946A (en) * 1981-12-23 1985-05-07 Hoechst-Roussel Pharmaceuticals Inc. 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives
US4526891A (en) * 1983-03-10 1985-07-02 Hoechst Roussel Pharmaceuticals Inc. Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins
US5008285A (en) * 1984-04-27 1991-04-16 Hoechst-Roussel Pharmaceuticals, Inc. (6,11-dihydro-11-oxodibenz[b,e]oxepin-yl)pentanoic acids and derivatives thereof
DE3573257D1 (en) * 1984-04-27 1989-11-02 Hoechst Roussel Pharma (6,11-dihydro-11-oxodibenz(bm,e)oxepinyl)pentanols, a process and intermediates for their preparation and their use as medicaments
US4861887A (en) * 1988-01-27 1989-08-29 American Cyanamid Company Herbicidal o-(substituted, aminomethylbenzoic, nicotinic and quinoline-3-carboxylic acids, esters, and salts
US7687646B2 (en) 2006-03-28 2010-03-30 Azad Pharmaceutical Ingredients, Ag Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof
CN106518833A (zh) * 2015-09-15 2017-03-22 江苏吉贝尔药业股份有限公司 一种新的6,11-二氢-11-氧代二苯并[b,e]噁庚因-2-乙酸制备方法

Also Published As

Publication number Publication date
CH594658A5 (fi) 1978-01-13
YU309481A (en) 1983-06-30
YU204274A (en) 1982-06-30
NL7409919A (nl) 1975-01-28
CH605899A5 (fi) 1978-10-13
AR210725A1 (es) 1977-09-15
CH605900A5 (fi) 1978-10-13
SE7705637L (sv) 1977-05-13
DK396874A (fi) 1975-03-17
YU309081A (en) 1983-06-30
NL159381B (nl) 1979-02-15
YU309381A (en) 1983-06-30
DE2435613B2 (de) 1979-07-05
AU7143174A (en) 1976-01-22
YU309281A (en) 1983-06-30
SE7409577L (fi) 1975-01-27
BE818055A (fr) 1974-11-18
CH605897A5 (fi) 1978-10-13
FR2245356B1 (fi) 1978-10-13
CH605896A5 (fi) 1978-10-13
CH605898A5 (fi) 1978-10-13
DE2435613A1 (de) 1975-02-27
FR2245356A1 (fi) 1975-04-25
GB1476215A (en) 1977-06-10
GB1476214A (en) 1977-06-10

Similar Documents

Publication Publication Date Title
CA1153383A (en) Dibenzoxepin derivatives and process for the preparation thereof
Okumura et al. 4-Oxo-1, 2, 3, 4-tetrahydroquinazolines. I. Syntheses and pharmacological properties of 2-methyl-3-aryl-4-oxo-1, 2, 3, 4-tetrahydroquinazolines and their 1-acyl derivatives
CA1153384A (en) 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives
US3984431A (en) Derivatives of pyrazole-5-acetic acid
JPS5811850B2 (ja) 1− オキソ −2,2− ジチカン −5− インダニロキシ ( マタハチオ # アルカノイツクアシド
CA1276938C (en) Arylacetic acid derivatives
US4247706A (en) Dibenzothiepin derivatives and a process for producing the same
FR2647676A1 (fr) Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase
US4011328A (en) Derivatives of pyridine-3-acetic acid, process for their preparation and applications thereof
US4057641A (en) Method of treating inflammation with 2-(2,3-dihydro-2-isopropyl-4-oxo-4H-1-benzopyran-6-yl)propionic acid
US3892774A (en) Cyclo pentathiophene derivatives
US4362891A (en) Alkanoic acid derivatives
US3506658A (en) 2-(10-methyl-2-phenoxazinyl)propionic acid
US4116972A (en) Anti-inflammatory 1-oxo-isoindoline derivatives and processes for their preparation
CA1063125A (en) (1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)) alkanoic acids and derivatives thereof and processes for preparing same
JPH0246035B2 (fi)
US3450698A (en) Phenthiazine derivatives
CA1276158C (en) 4h-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives
Bailey et al. 282. Synthetical experiments in the chelidonine–sanguinarine group of the alkaloids. Part II
Clark et al. The preparation of some thiochroman-3-ones and derivatives
CH392483A (fr) Procédé de préparation de nouveaux esters d'acides 4-halo-3-sulfamoyl-benzoïques
US4013692A (en) Certain 3-phenyl-benzofuran lower alkanoic acids and esters thereof
US4060550A (en) Novel n'-acylated phenyl-hydrazine and -hydrazone derivatives
CA1197511A (fr) Haloalkyl-8-4h-¬1|-benzopyran-4-ones, et procede de preparation
Lucien et al. THE SYNTHESIS OF DIBENZ [a, c][1, 3] CYCLOHEPTADIENE-5, 7-DIONE

Legal Events

Date Code Title Description
MKEX Expiry