CA1140212A - Method of and apparatus for monitoring platelet aggregation and test cell for use in such method apparatus - Google Patents
Method of and apparatus for monitoring platelet aggregation and test cell for use in such method apparatusInfo
- Publication number
- CA1140212A CA1140212A CA000336751A CA336751A CA1140212A CA 1140212 A CA1140212 A CA 1140212A CA 000336751 A CA000336751 A CA 000336751A CA 336751 A CA336751 A CA 336751A CA 1140212 A CA1140212 A CA 1140212A
- Authority
- CA
- Canada
- Prior art keywords
- electrodes
- sample
- test cell
- aggregation
- monitoring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 36
- 238000000034 method Methods 0.000 title claims abstract description 21
- 238000012544 monitoring process Methods 0.000 title claims abstract description 21
- 208000010110 spontaneous platelet aggregation Diseases 0.000 title claims abstract description 16
- 210000001772 blood platelet Anatomy 0.000 claims abstract description 46
- 210000004027 cell Anatomy 0.000 claims abstract description 45
- 230000002776 aggregation Effects 0.000 claims abstract description 20
- 238000004220 aggregation Methods 0.000 claims abstract description 20
- 230000008859 change Effects 0.000 claims abstract description 14
- 102000008186 Collagen Human genes 0.000 claims description 6
- 108010035532 Collagen Proteins 0.000 claims description 6
- 229920001436 collagen Polymers 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 3
- 210000004369 blood Anatomy 0.000 description 19
- 239000008280 blood Substances 0.000 description 19
- 230000003287 optical effect Effects 0.000 description 10
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 8
- 230000004931 aggregating effect Effects 0.000 description 7
- 239000003795 chemical substances by application Substances 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 230000004044 response Effects 0.000 description 6
- 238000003756 stirring Methods 0.000 description 5
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 4
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 229910052697 platinum Inorganic materials 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 230000023555 blood coagulation Effects 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 210000002381 plasma Anatomy 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 208000028702 Congenital thrombocyte disease Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 229940114079 arachidonic acid Drugs 0.000 description 2
- 235000021342 arachidonic acid Nutrition 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 description 2
- 229960001123 epoprostenol Drugs 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 229960000905 indomethacin Drugs 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 230000002427 irreversible effect Effects 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000002356 single layer Substances 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 208000037157 Azotemia Diseases 0.000 description 1
- 208000001593 Bernard-Soulier syndrome Diseases 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 208000013607 Glanzmann thrombasthenia Diseases 0.000 description 1
- 208000013544 Platelet disease Diseases 0.000 description 1
- 229910000971 Silver steel Inorganic materials 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 108090000190 Thrombin Proteins 0.000 description 1
- 208000027276 Von Willebrand disease Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000002051 biphasic effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 230000007248 cellular mechanism Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000005294 ferromagnetic effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 description 1
- 230000003760 hair shine Effects 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000012461 inherited thrombocytopenia Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 208000032345 macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss Diseases 0.000 description 1
- 230000005291 magnetic effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 210000004623 platelet-rich plasma Anatomy 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 210000001243 pseudopodia Anatomy 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 229960004072 thrombin Drugs 0.000 description 1
- 206010043554 thrombocytopenia Diseases 0.000 description 1
- 230000009424 thromboembolic effect Effects 0.000 description 1
- 208000009852 uremia Diseases 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 208000012137 von Willebrand disease (hereditary or acquired) Diseases 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
- G01N27/06—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
- G01N27/07—Construction of measuring vessels; Electrodes therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/05—Investigating sedimentation of particle suspensions in blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB39006/78 | 1978-10-02 | ||
| GB7839006 | 1978-10-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1140212A true CA1140212A (en) | 1983-01-25 |
Family
ID=10500059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000336751A Expired CA1140212A (en) | 1978-10-02 | 1979-10-01 | Method of and apparatus for monitoring platelet aggregation and test cell for use in such method apparatus |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4319194A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0010374B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS5550162A (cg-RX-API-DMAC7.html) |
| CA (1) | CA1140212A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2966583D1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI793043A7 (cg-RX-API-DMAC7.html) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5810573B2 (ja) * | 1978-11-21 | 1983-02-26 | 日産自動車株式会社 | 火花点火式内燃機関 |
| SE423829B (sv) * | 1980-09-29 | 1982-06-07 | Hedelin Lars G B | Kamanordning med roterbart kamorgan, vars form er variabel |
| JPS57168041A (en) * | 1981-04-09 | 1982-10-16 | Mazda Motor Corp | Engine idle rpm control device |
| US4543339A (en) * | 1982-03-16 | 1985-09-24 | Oneill Christopher | Early pregnancy detection by detecting enhanced blood platelet activation |
| US4591793A (en) * | 1984-06-14 | 1986-05-27 | Freilich Arthur H | Aggregometer electrode structures |
| GB8621757D0 (en) * | 1986-09-10 | 1986-10-15 | Gorog P | Blood testing device |
| GB8701368D0 (en) * | 1987-01-22 | 1987-02-25 | Ecc Int Ltd | Monitoring flocculation state of particles in suspension |
| US4986964A (en) * | 1990-04-19 | 1991-01-22 | Center For Innovative Technology | Clot retractometer |
| US5316730A (en) * | 1992-12-07 | 1994-05-31 | Xylum Corporation | Disposable cartridge for investigating physical properties of blood |
| US5447440A (en) * | 1993-10-28 | 1995-09-05 | I-Stat Corporation | Apparatus for assaying viscosity changes in fluid samples and method of conducting same |
| US6004819A (en) * | 1996-11-04 | 1999-12-21 | Xylum Corporation | Blood testing device |
| US6043871A (en) * | 1997-03-03 | 2000-03-28 | Brigham Young University | System and method for measuring blood platelet function |
| WO1998039643A1 (en) * | 1997-03-05 | 1998-09-11 | Diametrics | Method and apparatus for measurement of whole blood coagulation parameters |
| US6004818A (en) * | 1997-08-07 | 1999-12-21 | Chrono-Log Corporation | Aggregometer with disposable test cell |
| AU2003900285A0 (en) * | 2003-01-20 | 2003-02-06 | Universal Biosensors Pty Limited | Electrochemical detection method |
| AU2004206032B2 (en) * | 2003-01-20 | 2008-09-25 | Universal Biosensors Pty Limited | Electrochemical detection method |
| GB0313015D0 (en) * | 2003-06-06 | 2003-07-09 | Hall Effect Technologies Ltd | Method and device for analysing a liquid |
| CA2547544C (en) * | 2003-12-16 | 2013-04-02 | Dynabyte Informationssysteme Gmbh | Cartridge device for blood analysis |
| ES2425082T3 (es) | 2003-12-16 | 2013-10-11 | F. Hoffmann-La Roche Ag | Método de análisis de sangre |
| EP2063273A1 (en) * | 2007-11-21 | 2009-05-27 | Pentapharm GmbH | Method for assessing the fibrinogen contribution in coagulation |
| WO2009111615A2 (en) | 2008-03-05 | 2009-09-11 | Thrombovision, Inc. | Systems for measuring properties of a physiological fluid suspension |
| DE102008022884A1 (de) * | 2008-05-08 | 2009-11-12 | Zander, Rolf, Prof. Dr.Med. | Vorrichtung und Verfahren für die Blutgerinnungsdiagnostik |
| US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
| ES2692943T3 (es) * | 2008-12-23 | 2018-12-05 | C A Casyso Gmbh | Un dispositivo de cartucho para un sistema de medición para medir las características viscoelásticas de un líquido de muestra, un sistema de medición correspondiente y un procedimiento correspondiente |
| US8383045B2 (en) * | 2009-01-16 | 2013-02-26 | C A Casyso Ag | Measuring unit for measuring characteristics of a sample liquid, in particular viscoelastic characteristics of a blood sample |
| FR2955392B1 (fr) * | 2010-01-20 | 2017-11-17 | Comte Roger Le | Procede, dispositif et embout de mesure de vitesse d'agregation |
| EP2371284A1 (en) * | 2010-03-24 | 2011-10-05 | C A Casyso AG | Method and apparatus for determining at least one evaluation parameter of a blood sample |
| US8617468B2 (en) | 2011-10-18 | 2013-12-31 | Chrono-Log Corporation | Platelet aggregation test and device |
| US8772040B2 (en) * | 2012-08-31 | 2014-07-08 | Korea University Research And Business Foundation | Apparatus and method of platelet multi-function analysis, and micro stirring chip |
| JP2014115256A (ja) | 2012-12-12 | 2014-06-26 | Sony Corp | 電気的測定用容器、並びに電気的測定用装置および電気的測定方法 |
| BR112015016634A2 (pt) * | 2013-01-18 | 2017-07-11 | Sony Corp | dispositivo de medição de característica elétrica |
| JP6816792B2 (ja) * | 2014-01-07 | 2021-01-20 | ソニー株式会社 | 電気的測定用カートリッジ、並びに電気的測定装置及び電気的測定方法 |
| JP6569209B2 (ja) * | 2014-01-07 | 2019-09-04 | ソニー株式会社 | 電気的測定用カートリッジ、並びに電気的測定装置及び電気的測定方法 |
| US10288630B2 (en) | 2014-09-29 | 2019-05-14 | C A Casyso Gmbh | Blood testing system and method |
| US9897618B2 (en) | 2014-09-29 | 2018-02-20 | C A Casyso Gmbh | Blood testing system |
| US10175225B2 (en) | 2014-09-29 | 2019-01-08 | C A Casyso Ag | Blood testing system and method |
| US10816559B2 (en) | 2014-09-29 | 2020-10-27 | Ca Casyso Ag | Blood testing system and method |
| US10539579B2 (en) | 2014-09-29 | 2020-01-21 | C A Casyso Gmbh | Blood testing system and method |
| USD777343S1 (en) | 2015-05-28 | 2017-01-24 | C A Casyso Ag | Body fluid cartridge device |
| US10295554B2 (en) | 2015-06-29 | 2019-05-21 | C A Casyso Gmbh | Blood testing system and method |
| US20190049428A1 (en) * | 2016-02-17 | 2019-02-14 | Sony Corporation | Platelet aggregability analyzing device, platelet aggregability analyzing system, platelet aggregability analyzing program, and method of analyzing platelet aggregability |
| JP6070892B2 (ja) * | 2016-08-08 | 2017-02-01 | ソニー株式会社 | 電気的測定用容器、並びに電気的測定用装置および電気的測定方法 |
| US10473674B2 (en) | 2016-08-31 | 2019-11-12 | C A Casyso Gmbh | Controlled blood delivery to mixing chamber of a blood testing cartridge |
| US20200055044A1 (en) * | 2016-11-02 | 2020-02-20 | Atantares Corp. | Methods and systems for micro platelet function testing using an integrated miniaturized platelet function analyzer |
| JP6414234B2 (ja) * | 2017-01-05 | 2018-10-31 | ソニー株式会社 | 電気的測定用容器、並びに電気的測定用装置および電気的測定方法 |
| US10843185B2 (en) | 2017-07-12 | 2020-11-24 | Ca Casyso Gmbh | Autoplatelet cartridge device |
| JP6791220B2 (ja) * | 2018-09-18 | 2020-11-25 | ソニー株式会社 | 電気的測定用容器、並びに電気的測定装置および電気的測定方法 |
| CN114460153A (zh) * | 2022-01-27 | 2022-05-10 | 安邦（厦门）生物科技有限公司 | 一种用于检测全血血小板聚集功能的装置和方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2555937A (en) * | 1949-08-25 | 1951-06-05 | Robert L Rosenthal | Method and apparatus for measuring resistance of blood during clotting |
| US2651751A (en) * | 1949-12-14 | 1953-09-08 | Howard R Heath | Apparatus for measuring resistance |
| US2769141A (en) * | 1953-06-01 | 1956-10-30 | Indiana University Foundation | Apparatus for measuring blood coagulation time and enzyme activity |
| DE1022822B (de) | 1954-05-10 | 1958-01-16 | Dr Heinrich Schnitger | Apparat zur Ermittlung der Fibrinbildung im Blute oder in Blutplasmaloesungen und zum Registrieren der Blutgerinnungszeit |
| GB973807A (en) * | 1959-12-24 | 1964-10-28 | Yellow Springs Instr | Improvements in instruments for determining characteristics of blood |
| NL298730A (cg-RX-API-DMAC7.html) * | 1962-04-18 | |||
| US3267362A (en) * | 1962-04-18 | 1966-08-16 | Becton Dickinson Co | Electrode carrier assembly |
| US3524727A (en) * | 1965-06-16 | 1970-08-18 | Corning Glass Works | Method and device for determining serological data by an agglomeration test |
| US3555937A (en) * | 1968-05-17 | 1971-01-19 | Kennametal Inc | Diamond drill |
| GB1299363A (en) * | 1968-09-27 | 1972-12-13 | Amiram Ur | Monitoring of chemical, bio-chemical and biological reactions, particularly blood-clotting |
| FR2079841A5 (cg-RX-API-DMAC7.html) * | 1970-02-13 | 1971-11-12 | Girolami Antoine | |
| US3648159A (en) * | 1970-03-11 | 1972-03-07 | Us Air Force | Portable, self-contained system for analyzing biological fluids or the like |
| NL7303522A (cg-RX-API-DMAC7.html) * | 1973-03-13 | 1974-09-17 | ||
| US3840806A (en) * | 1973-08-20 | 1974-10-08 | G Stoner | Instrument for measuring blood clotting times |
| US3861877A (en) * | 1974-01-21 | 1975-01-21 | Clinical Technology Inc | Optical analysis of fluids |
| FR2301011A1 (fr) * | 1975-02-12 | 1976-09-10 | Inst Nat Sante Rech Med | Appareil combine formant agregometre et coagulometre |
| US4002739A (en) * | 1975-02-18 | 1977-01-11 | Warner-Lambert Company | Soluble collagen |
| US4027660A (en) * | 1976-04-02 | 1977-06-07 | Wardlaw Stephen C | Material layer volume determination |
-
1979
- 1979-10-01 DE DE7979302067T patent/DE2966583D1/de not_active Expired
- 1979-10-01 CA CA000336751A patent/CA1140212A/en not_active Expired
- 1979-10-01 JP JP12672079A patent/JPS5550162A/ja active Granted
- 1979-10-01 EP EP79302067A patent/EP0010374B1/en not_active Expired
- 1979-10-01 US US06/080,525 patent/US4319194A/en not_active Expired - Lifetime
- 1979-10-01 FI FI793043A patent/FI793043A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0010374A1 (en) | 1980-04-30 |
| FI793043A7 (fi) | 1981-01-01 |
| DE2966583D1 (en) | 1984-03-01 |
| JPS5550162A (en) | 1980-04-11 |
| EP0010374B1 (en) | 1984-01-25 |
| US4319194A (en) | 1982-03-09 |
| JPS6312261B2 (cg-RX-API-DMAC7.html) | 1988-03-18 |
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