CA1138451A - 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same - Google Patents

2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same

Info

Publication number
CA1138451A
CA1138451A CA000348207A CA348207A CA1138451A CA 1138451 A CA1138451 A CA 1138451A CA 000348207 A CA000348207 A CA 000348207A CA 348207 A CA348207 A CA 348207A CA 1138451 A CA1138451 A CA 1138451A
Authority
CA
Canada
Prior art keywords
amino
imidazoline
pharmaceutically acceptable
acceptable salts
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000348207A
Other languages
English (en)
French (fr)
Inventor
Ikuo Ueda
Masaaki Matsuo
Kiyoshi Taniguchi
Yousuke Katsura
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1138451A publication Critical patent/CA1138451A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000348207A 1979-04-03 1980-03-21 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same Expired CA1138451A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7911537 1979-04-03
GB7911537 1979-04-03

Publications (1)

Publication Number Publication Date
CA1138451A true CA1138451A (en) 1982-12-28

Family

ID=10504284

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000348207A Expired CA1138451A (en) 1979-04-03 1980-03-21 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same

Country Status (13)

Country Link
EP (1) EP0017484B1 (enExample)
JP (1) JPS55136266A (enExample)
AR (1) AR227556A1 (enExample)
AT (1) ATE2953T1 (enExample)
AU (1) AU535979B2 (enExample)
CA (1) CA1138451A (enExample)
DE (1) DE3062586D1 (enExample)
DK (1) DK142480A (enExample)
ES (1) ES490292A0 (enExample)
GR (1) GR66816B (enExample)
HU (1) HU184259B (enExample)
PH (1) PH15980A (enExample)
ZA (1) ZA801680B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521140A1 (fr) * 1982-02-05 1983-08-12 Synthelabo Derives d'imidazolidine, leur preparation et leur application en therapeutique
US4880838A (en) * 1982-06-30 1989-11-14 Rhone-Poulenc Pesticidal 1-(4-Phenoxyphenyl)-5-Benzoyl urea compounds and process for preparation
US4665097A (en) * 1983-03-31 1987-05-12 Union Carbide Corporation Novel bicyclooxyaryl thioureas and process for preparation
US4873264A (en) * 1983-05-20 1989-10-10 Rhone-Poulenc Nederlands B.V. Novel pesticidal 1-(alkyl-phenoxy-aryl)-3-benzoyl ureas and process for preparation
US4638088A (en) * 1984-11-15 1987-01-20 Union Carbide Corporation Pesticidal biphenylyloxy and biphenylylalkoxy aryl acyl urea compounds
US5290814A (en) * 1988-11-21 1994-03-01 Burroughs Wellcome Co. Anti-atherosclerotic diaryl compounds
GB8827152D0 (en) * 1988-11-21 1988-12-29 Wellcome Found Anti-atherosclerotic diaryl compounds
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
US5001157A (en) * 1989-02-02 1991-03-19 American Cyanamid Company Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides
IN172842B (enExample) * 1990-05-17 1993-12-11 Boots Pharmaceuticals Limited
JPH0440953A (ja) * 1990-06-05 1992-02-12 Kyodo Sekkei:Kk 注射針処理方法及びその装置
CN1037346C (zh) * 1990-06-29 1998-02-11 布茨公司 降血糖的脒类和胍类的制备方法
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
NZ331480A (en) * 1997-09-04 2000-02-28 F 2-(Arylphenyl)amino-imidazoline derivatives and pharmaceutical compositions
US6184242B1 (en) 1997-09-04 2001-02-06 Syntex Usa (Llc) 2-(substituted-phenyl)amino-imidazoline derivatives
US6417186B1 (en) 2000-11-14 2002-07-09 Syntex (U.S.A.) Llc Substituted-phenyl ketone derivatives as IP antagonists
BRPI0409957A (pt) 2003-05-01 2006-04-25 Hoffmann La Roche imidazolin-2-ilaminofenil amidas
BRPI0411867A (pt) * 2003-07-09 2006-08-08 Hoffmann La Roche tiofenilaminoimidazolinas
MXPA06000418A (es) * 2003-07-10 2006-04-05 Achillion Pharmaceuticals Inc Derivados de ariltiourea sustituida utiles como inhibidores de duplicacion viral.
TW200628153A (en) * 2004-10-05 2006-08-16 Smithkline Beecham Corp Novel compounds
DE102005007160A1 (de) * 2005-02-16 2006-08-24 Basf Ag Pyrazolcarbonsäureanilide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB889706A (en) * 1960-07-16 1962-02-21 Thomas Adam Clayton Fungicidal composition
DE2446758C3 (de) * 1974-10-01 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie

Also Published As

Publication number Publication date
PH15980A (en) 1983-05-16
GR66816B (enExample) 1981-04-30
ATE2953T1 (de) 1983-04-15
EP0017484A1 (en) 1980-10-15
AU5689280A (en) 1980-10-09
DE3062586D1 (en) 1983-05-11
ES8103053A1 (es) 1981-02-16
JPS55136266A (en) 1980-10-23
JPH0210830B2 (enExample) 1990-03-09
HU184259B (en) 1984-07-30
DK142480A (da) 1980-10-04
ES490292A0 (es) 1981-02-16
AR227556A1 (es) 1982-11-15
EP0017484B1 (en) 1983-04-06
ZA801680B (en) 1981-03-25
AU535979B2 (en) 1984-04-12

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Legal Events

Date Code Title Description
MKEX Expiry