CA1113455A - 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-3-triazolo ¬4,3-b| pyridazin-3-on-6-ylthiomethyl)-3-cephem- 4-carboxylic acids - Google Patents

7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-3-triazolo ¬4,3-b| pyridazin-3-on-6-ylthiomethyl)-3-cephem- 4-carboxylic acids

Info

Publication number
CA1113455A
CA1113455A CA287,569A CA287569A CA1113455A CA 1113455 A CA1113455 A CA 1113455A CA 287569 A CA287569 A CA 287569A CA 1113455 A CA1113455 A CA 1113455A
Authority
CA
Canada
Prior art keywords
hydrogen
methyl
compound
acid
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA287,569A
Other languages
English (en)
French (fr)
Inventor
Takayuki Naito
Hajime Kamachi
Jun Okumura
Seiji Iimura
Hideaki Hoshi
Masahisa Oka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/784,885 external-priority patent/US4082912A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1113455A publication Critical patent/CA1113455A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA287,569A 1977-04-05 1977-09-27 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-3-triazolo ¬4,3-b| pyridazin-3-on-6-ylthiomethyl)-3-cephem- 4-carboxylic acids Expired CA1113455A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/784,885 US4082912A (en) 1976-06-30 1977-04-05 Certain 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylmethyl)-3-cephem-4-carboxylic acids their salts and easily hydrolyzed esters
US784,885 1977-04-05

Publications (1)

Publication Number Publication Date
CA1113455A true CA1113455A (en) 1981-12-01

Family

ID=25133827

Family Applications (1)

Application Number Title Priority Date Filing Date
CA287,569A Expired CA1113455A (en) 1977-04-05 1977-09-27 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-3-triazolo ¬4,3-b| pyridazin-3-on-6-ylthiomethyl)-3-cephem- 4-carboxylic acids

Country Status (17)

Country Link
JP (1) JPS53124290A (el)
AU (1) AU517919B2 (el)
BE (1) BE859774A (el)
CA (1) CA1113455A (el)
CH (1) CH627184A5 (el)
DE (1) DE2807847A1 (el)
DK (1) DK145497C (el)
FI (1) FI60869C (el)
FR (1) FR2408614A1 (el)
GB (1) GB1572201A (el)
GR (1) GR73550B (el)
IE (1) IE45613B1 (el)
LU (1) LU78323A1 (el)
NL (1) NL7711644A (el)
SE (1) SE425491B (el)
YU (1) YU247977A (el)
ZA (1) ZA775781B (el)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114940665A (zh) * 2022-06-10 2022-08-26 河南省科学院高新技术研究中心 一种用作杀菌剂的苯并异噻唑啉酮类化合物及其制备方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907786A (en) * 1973-09-04 1975-09-23 Bristol Myers Co 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114940665A (zh) * 2022-06-10 2022-08-26 河南省科学院高新技术研究中心 一种用作杀菌剂的苯并异噻唑啉酮类化合物及其制备方法
CN114940665B (zh) * 2022-06-10 2024-05-07 河南省科学院高新技术研究中心 一种用作杀菌剂的苯并异噻唑啉酮类化合物及其制备方法

Also Published As

Publication number Publication date
DK145497C (da) 1983-05-02
BE859774A (fr) 1978-04-14
ZA775781B (en) 1978-08-30
NL7711644A (nl) 1978-10-09
DE2807847A1 (de) 1978-10-19
JPS53124290A (en) 1978-10-30
FI60869B (fi) 1981-12-31
DK145497B (da) 1982-11-29
YU247977A (en) 1982-10-31
GR73550B (el) 1984-03-13
GB1572201A (en) 1980-07-23
FI772860A (fi) 1978-10-06
DK429577A (da) 1978-10-06
LU78323A1 (el) 1978-06-12
SE425491B (sv) 1982-10-04
IE45613B1 (en) 1982-10-06
FR2408614A1 (fr) 1979-06-08
AU517919B2 (en) 1981-09-03
SE7710823L (sv) 1978-10-06
CH627184A5 (en) 1981-12-31
FR2408614B1 (el) 1980-12-05
IE45613L (en) 1978-10-05
FI60869C (fi) 1982-04-13
AU2932877A (en) 1979-04-12

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