CA1108159A - Substituted 4-(((2-thienyl)methyl)amino) benzoic acids and a method for treating hypolipidemia - Google Patents

Substituted 4-(((2-thienyl)methyl)amino) benzoic acids and a method for treating hypolipidemia

Info

Publication number
CA1108159A
CA1108159A CA300,577A CA300577A CA1108159A CA 1108159 A CA1108159 A CA 1108159A CA 300577 A CA300577 A CA 300577A CA 1108159 A CA1108159 A CA 1108159A
Authority
CA
Canada
Prior art keywords
chloro
benzoic acid
compounds
amino
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA300,577A
Other languages
English (en)
French (fr)
Inventor
Eugene R. Wagner
Donald P. Matthews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Application granted granted Critical
Publication of CA1108159A publication Critical patent/CA1108159A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA300,577A 1977-04-07 1978-04-06 Substituted 4-(((2-thienyl)methyl)amino) benzoic acids and a method for treating hypolipidemia Expired CA1108159A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78546777A 1977-04-07 1977-04-07
US785,467 1991-10-31

Publications (1)

Publication Number Publication Date
CA1108159A true CA1108159A (en) 1981-09-01

Family

ID=25135597

Family Applications (1)

Application Number Title Priority Date Filing Date
CA300,577A Expired CA1108159A (en) 1977-04-07 1978-04-06 Substituted 4-(((2-thienyl)methyl)amino) benzoic acids and a method for treating hypolipidemia

Country Status (14)

Country Link
JP (1) JPS53149968A (it)
BE (1) BE865809A (it)
CA (1) CA1108159A (it)
CH (1) CH629796A5 (it)
DE (1) DE2814798A1 (it)
DK (1) DK153403C (it)
FR (1) FR2386542A1 (it)
GB (1) GB1565936A (it)
IE (1) IE46713B1 (it)
IT (1) IT1094318B (it)
NL (1) NL7803669A (it)
NO (1) NO149241C (it)
NZ (1) NZ186886A (it)
SE (1) SE446734B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143151A (en) * 1978-07-03 1979-03-06 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids
JPS6421196A (en) * 1987-07-15 1989-01-24 Nippon Concrete Ind Co Ltd Auger screw

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2983729A (en) * 1958-04-30 1961-05-09 Monsanto Chemicals Preparation of 5-halothienyl amines
US3859440A (en) * 1971-10-08 1975-01-07 Ici Australia Ltd Certain thienyl compounds used to control acarina
US4185115A (en) * 1975-03-12 1980-01-22 American Cyanamid Company Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives

Also Published As

Publication number Publication date
IT1094318B (it) 1985-07-26
JPS53149968A (en) 1978-12-27
DK153178A (da) 1978-10-08
NZ186886A (en) 1980-02-21
JPS6126790B2 (it) 1986-06-21
BE865809A (fr) 1978-10-09
DE2814798C2 (it) 1988-05-26
DK153403B (da) 1988-07-11
NO149241C (no) 1984-03-14
NL7803669A (nl) 1978-10-10
DK153403C (da) 1988-11-28
NO149241B (no) 1983-12-05
IE46713B1 (en) 1983-09-07
SE7803910L (sv) 1978-10-08
CH629796A5 (en) 1982-05-14
NO781214L (no) 1978-10-10
IE780678L (en) 1978-10-07
SE446734B (sv) 1986-10-06
FR2386542A1 (fr) 1978-11-03
DE2814798A1 (de) 1978-10-19
FR2386542B1 (it) 1981-07-10
IT7821941A0 (it) 1978-04-04
GB1565936A (en) 1980-04-23

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Legal Events

Date Code Title Description
MKEX Expiry