CA1104925A - Composition and method for treating or preventing fowl coccidiosis - Google Patents
Composition and method for treating or preventing fowl coccidiosisInfo
- Publication number
- CA1104925A CA1104925A CA295,285A CA295285A CA1104925A CA 1104925 A CA1104925 A CA 1104925A CA 295285 A CA295285 A CA 295285A CA 1104925 A CA1104925 A CA 1104925A
- Authority
- CA
- Canada
- Prior art keywords
- composition
- coccidiosis
- macrotetrolide
- treating
- ppm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 208000003495 Coccidiosis Diseases 0.000 title claims abstract description 20
- 206010023076 Isosporiasis Diseases 0.000 title claims abstract description 20
- 239000000203 mixture Substances 0.000 title claims abstract description 20
- 230000003405 preventing effect Effects 0.000 title claims abstract description 8
- 238000000034 method Methods 0.000 title abstract description 10
- 239000000126 substance Substances 0.000 claims abstract description 15
- 230000003115 biocidal effect Effects 0.000 claims abstract description 12
- 239000003120 macrolide antibiotic agent Substances 0.000 claims abstract description 9
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 5
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims abstract 3
- CTZNINKRTKCWGU-UHFFFAOYSA-N Dinactin Natural products CC1C(=O)OC(C)CC(O2)CCC2C(C)C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(C)CC2CCC1O2 CTZNINKRTKCWGU-UHFFFAOYSA-N 0.000 claims description 7
- ZBDGIMZKOJALMU-MVWQHRGOSA-N dinactin Chemical compound C[C@@H]([C@@H]1CC[C@@H](O1)C[C@@H](OC(=O)[C@@H](C)[C@H]1CC[C@H](O1)C[C@@H](C)OC(=O)[C@@H](C)[C@@H]1CC[C@@H](O1)C[C@H](CC)OC(=O)[C@H]1C)CC)C(=O)O[C@H](C)C[C@@H]2CC[C@H]1O2 ZBDGIMZKOJALMU-MVWQHRGOSA-N 0.000 claims description 7
- DFQMKYUSAALDDY-MQEBUAKTSA-N trinactin Chemical compound C[C@@H]([C@@H]1CC[C@@H](O1)C[C@H](OC(=O)[C@H](C)[C@H]1CC[C@H](O1)C[C@H](CC)OC(=O)[C@@H](C)[C@@H]1CC[C@@H](O1)C[C@@H](CC)OC(=O)[C@@H]1C)CC)C(=O)O[C@@H](C)C[C@@H]2CC[C@H]1O2 DFQMKYUSAALDDY-MQEBUAKTSA-N 0.000 claims description 7
- DFQMKYUSAALDDY-UHFFFAOYSA-N trinactin Natural products CC1C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(C)CC2CCC1O2 DFQMKYUSAALDDY-UHFFFAOYSA-N 0.000 claims description 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- NKNPHSJWQZXWIX-DCVDGXQQSA-N Tetranactin Chemical compound C[C@H]([C@H]1CC[C@H](O1)C[C@@H](OC(=O)[C@@H](C)[C@@H]1CC[C@@H](O1)C[C@@H](CC)OC(=O)[C@H](C)[C@H]1CC[C@H](O1)C[C@H](CC)OC(=O)[C@H]1C)CC)C(=O)O[C@H](CC)C[C@H]2CC[C@@H]1O2 NKNPHSJWQZXWIX-DCVDGXQQSA-N 0.000 claims description 6
- NKNPHSJWQZXWIX-UHFFFAOYSA-N Tetranactin Natural products CC1C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(CC)CC(O2)CCC2C(C)C(=O)OC(CC)CC2CCC1O2 NKNPHSJWQZXWIX-UHFFFAOYSA-N 0.000 claims description 6
- 229920002261 Corn starch Polymers 0.000 claims description 3
- RMIXHJPMNBXMBU-QIIXEHPYSA-N Nonactin Chemical compound C[C@H]([C@H]1CC[C@H](O1)C[C@@H](OC(=O)[C@@H](C)[C@@H]1CC[C@@H](O1)C[C@@H](C)OC(=O)[C@H](C)[C@H]1CC[C@H](O1)C[C@H](C)OC(=O)[C@H]1C)C)C(=O)O[C@H](C)C[C@H]2CC[C@@H]1O2 RMIXHJPMNBXMBU-QIIXEHPYSA-N 0.000 claims description 3
- RMIXHJPMNBXMBU-UHFFFAOYSA-N Nonactin Natural products CC1C(=O)OC(C)CC(O2)CCC2C(C)C(=O)OC(C)CC(O2)CCC2C(C)C(=O)OC(C)CC(O2)CCC2C(C)C(=O)OC(C)CC2CCC1O2 RMIXHJPMNBXMBU-UHFFFAOYSA-N 0.000 claims description 3
- 240000007594 Oryza sativa Species 0.000 claims description 3
- 235000007164 Oryza sativa Nutrition 0.000 claims description 3
- 235000019764 Soybean Meal Nutrition 0.000 claims description 3
- 241000209140 Triticum Species 0.000 claims description 3
- 235000021307 Triticum Nutrition 0.000 claims description 3
- 239000008120 corn starch Substances 0.000 claims description 3
- 235000012054 meals Nutrition 0.000 claims description 3
- -1 monoactin Chemical compound 0.000 claims description 3
- 235000009566 rice Nutrition 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- 239000004455 soybean meal Substances 0.000 claims description 3
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 231100000915 pathological change Toxicity 0.000 description 12
- 230000036285 pathological change Effects 0.000 description 12
- 210000000813 small intestine Anatomy 0.000 description 12
- 210000004534 cecum Anatomy 0.000 description 11
- 241000287828 Gallus gallus Species 0.000 description 9
- 210000003250 oocyst Anatomy 0.000 description 7
- 238000012360 testing method Methods 0.000 description 6
- 235000013330 chicken meat Nutrition 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 210000004877 mucosa Anatomy 0.000 description 5
- 230000001575 pathological effect Effects 0.000 description 5
- 210000000664 rectum Anatomy 0.000 description 5
- 241000272496 Galliformes Species 0.000 description 4
- 238000009395 breeding Methods 0.000 description 4
- 230000001488 breeding effect Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 230000002008 hemorrhagic effect Effects 0.000 description 4
- 230000000069 prophylactic effect Effects 0.000 description 4
- 241000223924 Eimeria Species 0.000 description 3
- 238000007792 addition Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000017074 necrotic cell death Effects 0.000 description 3
- 206010003694 Atrophy Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 241000286209 Phasianidae Species 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000037444 atrophy Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 210000001198 duodenum Anatomy 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000272525 Anas platyrhynchos Species 0.000 description 1
- 241000224483 Coccidia Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000223931 Eimeria acervulina Species 0.000 description 1
- 241000499563 Eimeria necatrix Species 0.000 description 1
- 241000223932 Eimeria tenella Species 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010037549 Purpura Diseases 0.000 description 1
- 241000519995 Stachys sylvatica Species 0.000 description 1
- 239000000642 acaricide Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000002133 anti-thiamin Effects 0.000 description 1
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N ferric oxide Chemical compound O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 210000003736 gastrointestinal content Anatomy 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 206010034754 petechiae Diseases 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 description 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Polymers & Plastics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4979/77 | 1977-01-21 | ||
| JP497977A JPS5391143A (en) | 1977-01-21 | 1977-01-21 | Anticoccidiosis agent for cattle and poultry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1104925A true CA1104925A (en) | 1981-07-14 |
Family
ID=11598708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA295,285A Expired CA1104925A (en) | 1977-01-21 | 1978-01-19 | Composition and method for treating or preventing fowl coccidiosis |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4136191A (en:Method) |
| JP (1) | JPS5391143A (en:Method) |
| CA (1) | CA1104925A (en:Method) |
| DE (1) | DE2802455C2 (en:Method) |
| FR (1) | FR2377803A1 (en:Method) |
| GB (1) | GB1570577A (en:Method) |
| IT (1) | IT1102815B (en:Method) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5930060B2 (ja) * | 1977-08-18 | 1984-07-25 | 日本化薬株式会社 | 動物用発育促進剤 |
| JPS57175118A (en) * | 1981-04-21 | 1982-10-28 | Kaken Pharmaceut Co Ltd | Feed efficiency improver and coccidioidis preventive or remedy |
| US6608033B1 (en) * | 1999-08-27 | 2003-08-19 | Pfizer Inc. | Treatment or prevention of coccidiosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3150042A (en) * | 1963-03-15 | 1964-09-22 | Upjohn Co | Treating coccidiosis with lincomycin |
| GB1318708A (en) * | 1969-09-06 | 1973-05-31 | Chugai Pharmaceutical Co Ltd | Agricultural compositions and methods of controlling mites and insects |
-
1977
- 1977-01-21 JP JP497977A patent/JPS5391143A/ja active Pending
-
1978
- 1978-01-18 US US05/870,487 patent/US4136191A/en not_active Expired - Lifetime
- 1978-01-19 CA CA295,285A patent/CA1104925A/en not_active Expired
- 1978-01-20 IT IT47732/78A patent/IT1102815B/it active
- 1978-01-20 FR FR7801699A patent/FR2377803A1/fr active Granted
- 1978-01-20 DE DE2802455A patent/DE2802455C2/de not_active Expired
- 1978-01-20 GB GB2417/78A patent/GB1570577A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4136191A (en) | 1979-01-23 |
| IT7847732A0 (it) | 1978-01-20 |
| DE2802455C2 (de) | 1982-10-21 |
| DE2802455A1 (de) | 1978-07-27 |
| IT1102815B (it) | 1985-10-07 |
| FR2377803A1 (fr) | 1978-08-18 |
| JPS5391143A (en) | 1978-08-10 |
| FR2377803B1 (en:Method) | 1981-07-03 |
| GB1570577A (en) | 1980-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |