CA1088528A - Method of producing 2-halomethyl-1,4-benzodiazepines - Google Patents

Method of producing 2-halomethyl-1,4-benzodiazepines

Info

Publication number
CA1088528A
CA1088528A CA237,301A CA237301A CA1088528A CA 1088528 A CA1088528 A CA 1088528A CA 237301 A CA237301 A CA 237301A CA 1088528 A CA1088528 A CA 1088528A
Authority
CA
Canada
Prior art keywords
formula
solvent
halomethyl
phosphorus
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA237,301A
Other languages
English (en)
French (fr)
Inventor
Horst Zeugner
Wolfgang Milkowski
Hans Liepmann
Siegfried Funke
Werner Stuhmer
Rolf Huschens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Application granted granted Critical
Publication of CA1088528A publication Critical patent/CA1088528A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA237,301A 1974-10-10 1975-10-06 Method of producing 2-halomethyl-1,4-benzodiazepines Expired CA1088528A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP2448259.5 1974-10-10
DE19742448259 DE2448259A1 (de) 1974-10-10 1974-10-10 Verfahren zur herstellung von 2-halogenmethyl-1,4-benzodiazepinen

Publications (1)

Publication Number Publication Date
CA1088528A true CA1088528A (en) 1980-10-28

Family

ID=5927957

Family Applications (1)

Application Number Title Priority Date Filing Date
CA237,301A Expired CA1088528A (en) 1974-10-10 1975-10-06 Method of producing 2-halomethyl-1,4-benzodiazepines

Country Status (13)

Country Link
JP (1) JPS5165786A (nl)
AR (1) AR205941A1 (nl)
AT (1) AT346340B (nl)
CA (1) CA1088528A (nl)
CH (1) CH614199A5 (nl)
CS (2) CS184800B2 (nl)
DD (1) DD121788A5 (nl)
DE (1) DE2448259A1 (nl)
FI (1) FI752802A (nl)
GR (1) GR58594B (nl)
HU (1) HU173342B (nl)
NL (1) NL7511724A (nl)
SE (1) SE422206B (nl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES469020A1 (es) * 1977-05-10 1979-09-01 Kali Chemie Pharma Gmbh Procedimiento para la preparacion de nuevos 1-acil-2-hidroxi-1,3-diaminopropanos
DE2720968C2 (de) * 1977-05-10 1986-05-07 Kali-Chemie Pharma Gmbh, 3000 Hannover N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel
US8426761B2 (en) 2009-10-21 2013-04-23 Fanuc Ltd Method of detection of welding workpiece position using movable electrode

Also Published As

Publication number Publication date
GR58594B (en) 1977-11-10
CS184790B2 (en) 1978-09-15
SE422206B (sv) 1982-02-22
ATA772175A (de) 1978-03-15
HU173342B (hu) 1979-04-28
JPS5165786A (en) 1976-06-07
SE7511324L (sv) 1976-04-12
FI752802A (nl) 1976-04-11
NL7511724A (nl) 1976-04-13
CH614199A5 (en) 1979-11-15
AT346340B (de) 1978-11-10
DE2448259A1 (de) 1976-04-22
CS184800B2 (en) 1978-09-15
DD121788A5 (nl) 1976-08-20
JPS6218554B2 (nl) 1987-04-23
AR205941A1 (es) 1976-06-15

Similar Documents

Publication Publication Date Title
US4098786A (en) Benzodiazepin derivatives
Sternbach et al. Quinazolines and 1, 4-Benzodiazepines. VI. 1a Halo-, Methyl-, and Methoxy-substituted 1, 3-Dihydro-5-phenyl-2H-1, 4-benzodiazepin-2-ones1b, c
US4108852A (en) Process for preparing 1,5-benzodiazepine-2-ones
USRE30293E (en) Process for preparing 1,5-benzodiazepine-2-ones
CA1326035C (en) Process for the preparation of substituted quinolines
NO853255L (no) Fremgangsmaate for fremstilling av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-benzazepin.
US5034541A (en) Method of preparing 1-phenyl-1-diethylaminocarbonyl-2-phthalimidomethyl-cyclopropane-z
CA1088528A (en) Method of producing 2-halomethyl-1,4-benzodiazepines
US3267107A (en) 3-(4'-5'-methylenedioxy-phenyl)-7, 8-dimethoxy-1, 2, 3, 4,-tetrahydroisoquinolines
JPH0433791B2 (nl)
KR20020019902A (ko) 피페라진 고리 함유 화합물의 신규한 합성법 및 결정화법
US6197976B1 (en) Preparation of ketorolac
US4634768A (en) Halo-containing 3-methylflavone-8-carboxylic acid derivatives
NL8002610A (nl) Heterocyclische verbindingen en werkwijzen voor het bereiden en toepassen van deze verbindingen.
CA1100960A (en) 3-fluorobenzodiazepines
EP0008446B1 (en) Process for the preparation of carbazoles and novel carbazole derivatives utilized therein
US4102881A (en) Benzodiazepine derivatives
US3872089A (en) Substituted thienodiazepines
US4244869A (en) Benzodiazepine derivatives and process of making them
US4239684A (en) 1,5'-Benzodiazepine-2-ones, pharmaceutical compositions thereof and method of use thereof
US3927015A (en) 2-(3-Hydroxyaminomethyl-S-triazol-4-yl)benzophenones
US3182065A (en) 2-acetamidobenzoyl-pyridines
US3215737A (en) Preparation of 2-amino-5-nitro-benzophenone and derivatives thereof
CA1154027A (en) Derivatives of benzo¬b| furan
US3991070A (en) Process for preparing halo triazolo benzodiazepine

Legal Events

Date Code Title Description
MKEX Expiry