CA1078731A - Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid) - Google Patents

Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)

Info

Publication number
CA1078731A
CA1078731A CA268,001A CA268001A CA1078731A CA 1078731 A CA1078731 A CA 1078731A CA 268001 A CA268001 A CA 268001A CA 1078731 A CA1078731 A CA 1078731A
Authority
CA
Canada
Prior art keywords
triethylene tetramine
phosphonic acid
methylene phosphonic
kit
tetramine hexa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA268,001A
Other languages
English (en)
French (fr)
Inventor
Richard E. Rolleston
Jacques A. Nadeau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Charles E Frosst and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charles E Frosst and Co filed Critical Charles E Frosst and Co
Priority to CA268,001A priority Critical patent/CA1078731A/en
Priority to US05/838,709 priority patent/US4187284A/en
Priority to NL7713161A priority patent/NL7713161A/xx
Priority to FR7737497A priority patent/FR2374014A1/fr
Priority to JP15074877A priority patent/JPS5377016A/ja
Priority to BE183512A priority patent/BE861923A/xx
Application granted granted Critical
Publication of CA1078731A publication Critical patent/CA1078731A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA268,001A 1976-12-16 1976-12-16 Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid) Expired CA1078731A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA268,001A CA1078731A (en) 1976-12-16 1976-12-16 Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)
US05/838,709 US4187284A (en) 1976-12-16 1977-10-03 Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)
NL7713161A NL7713161A (nl) 1976-12-16 1977-11-29 Kit voor de bereiding van een injiceerbare tech- netium-99m bevattende oplossing alsmede werkwijze voor het bereiden van een verbeterde injiceerbare oplossing voor beenderbeeldvorming.
FR7737497A FR2374014A1 (fr) 1976-12-16 1977-12-13 Ensemble de fournitures pour la formation d'images du squelette utilisant du triethylene tetramine hexa (acide methylene phosphonique)
JP15074877A JPS5377016A (en) 1976-12-16 1977-12-16 Scaffold reflection kit utilizing triethylene tetramine hexa*methylene phosphonate
BE183512A BE861923A (fr) 1976-12-16 1977-12-16 Ensemble de fournitures pour la formation d'images du squelette utilisant du triethylene tetramine hexa(acide methylene phosphonique)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA268,001A CA1078731A (en) 1976-12-16 1976-12-16 Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)

Publications (1)

Publication Number Publication Date
CA1078731A true CA1078731A (en) 1980-06-03

Family

ID=4107511

Family Applications (1)

Application Number Title Priority Date Filing Date
CA268,001A Expired CA1078731A (en) 1976-12-16 1976-12-16 Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)

Country Status (6)

Country Link
US (1) US4187284A (oth)
JP (1) JPS5377016A (oth)
BE (1) BE861923A (oth)
CA (1) CA1078731A (oth)
FR (1) FR2374014A1 (oth)
NL (1) NL7713161A (oth)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0164843A3 (en) * 1984-06-04 1987-09-23 The Dow Chemical Company Organic amine phosphonic acid complexes for the treatment of calcific tumors
US4898724A (en) * 1984-06-04 1990-02-06 The Dow Chemical Company Organis amine phosphonic acid complexes for the treatment of calcific tumors
US6767531B2 (en) 1999-07-11 2004-07-27 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US7115720B2 (en) 2001-01-08 2006-10-03 Neorx Corporation Therapeutic and diagnostic compounds, compositions, and methods

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515766A (en) * 1980-06-23 1985-05-07 The Massachusetts General Hospital Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium
US4504463A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
GB8310438D0 (en) * 1983-04-18 1983-05-25 Amersham Int Plc Bone-seeking complexes of technetium-99m
US4582698A (en) * 1983-09-19 1986-04-15 The Dow Chemical Company Process for imaging cardiac infarcts
IL74386A (en) * 1984-02-27 1988-12-30 Dow Chemical Co Bis(aminomethyl)bicyclo(2.2.1)heptanes useful as metal ion control agents
US4560548A (en) * 1984-04-10 1985-12-24 The Dow Chemical Company Bone seeking Tc-99m complexes of phosphonate derivatives of bis(aminoalkyl)piperazine
US5059412A (en) * 1984-06-04 1991-10-22 The Dow Chemical Company Macrocyclic aminophosphonic acid complexes for the treatment of calcific tumors
JPS6117596A (ja) * 1984-07-03 1986-01-25 Fujisawa Pharmaceut Co Ltd ホスミドマイシンまたはその塩類の凍結乾燥粉体およびその製造法
FR2636632B1 (fr) * 1988-09-16 1996-02-02 Oris Ind Produits radiopharmaceutiques constitues par des complexes de tc, re ou y comportant des ligands tetraphosphonates et leur preparation
US20060008422A1 (en) * 2004-01-09 2006-01-12 Abraham Araya Dentifrice compositons and abrasive systems
GB0400408D0 (en) * 2004-01-09 2004-02-11 Ineos Silicas Ltd Dentifrice compositions containing zeolites
DE102014210378B4 (de) 2014-06-02 2018-10-04 Zschimmer & Schwarz Mohsdorf GmbH &Co.KG. Verfahren zur Herstellung hochreiner Aminoalkylenphosphonsäuren
TWI902661B (zh) 2018-05-04 2025-11-01 法商奧法蘭股份公司 三伸乙基四胺四鹽酸鹽之結晶型及其醫藥用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2017974A1 (de) * 1970-04-15 1971-11-04 Joh. A. Benckiser Gmbh Chemische Fabrik, 6700 Ludwigshafen Verfahren zur Herstellung von Aminoalkylenphosphonsäuren
US3983227A (en) * 1973-05-23 1976-09-28 The Procter & Gamble Company Dry mixture containing diphosphonates and a stannous salt useful in the preparation of Tc99M containing bone scanning agents
CA1027135A (en) * 1973-06-11 1978-02-28 Research Corporation Bone-seeking technetium-99m complex
US3974268A (en) * 1975-05-30 1976-08-10 Research Corporation Bone-seeking technetium-99m imidodiphosphonate complex
US4017595A (en) * 1975-08-28 1977-04-12 Research Corporation Bone-seeking indium-113m or indium-111 organic phosphonate complexes

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0164843A3 (en) * 1984-06-04 1987-09-23 The Dow Chemical Company Organic amine phosphonic acid complexes for the treatment of calcific tumors
US4898724A (en) * 1984-06-04 1990-02-06 The Dow Chemical Company Organis amine phosphonic acid complexes for the treatment of calcific tumors
US5300279A (en) * 1984-06-04 1994-04-05 The Dow Chemical Company Organic amine phosphonic acid complexes for the treatment of calcific tumors
US7097823B2 (en) 1999-07-11 2006-08-29 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7070759B2 (en) 1999-07-11 2006-07-04 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US6767531B2 (en) 1999-07-11 2004-07-27 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7378077B2 (en) 1999-07-11 2008-05-27 Poniard Pharmaceuticals, Inc. High dose radionuclide complexes for bone marrow suppression
US7408046B2 (en) 1999-07-11 2008-08-05 Poniard Pharmaceuticals, Inc. Treatment of bone-associated cancers
US7605239B2 (en) 1999-07-11 2009-10-20 Poniard Pharmaceuticals, Inc. Skeletal-targeted radiation to treat bone-associated pathologies
US7691985B2 (en) 1999-07-11 2010-04-06 Poniard Pharmaceuticals, Inc. Skeletal-targeted radiation to treat bone-associated pathologies
US7696331B2 (en) 1999-07-11 2010-04-13 Poniard Pharmaceuticals, Inc. High dose radionuclide complexes for bone marrow treatment
US7115720B2 (en) 2001-01-08 2006-10-03 Neorx Corporation Therapeutic and diagnostic compounds, compositions, and methods
US7385042B2 (en) 2001-01-08 2008-06-10 Poniard Pharmaceuticals, Inc. Therapeutic and diagnostic compounds, compositions, and methods

Also Published As

Publication number Publication date
BE861923A (fr) 1978-06-16
FR2374014A1 (fr) 1978-07-13
FR2374014B1 (oth) 1980-04-04
NL7713161A (nl) 1978-06-20
US4187284A (en) 1980-02-05
JPS5377016A (en) 1978-07-08

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Legal Events

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