FR2636632B1 - Produits radiopharmaceutiques constitues par des complexes de tc, re ou y comportant des ligands tetraphosphonates et leur preparation - Google Patents

Produits radiopharmaceutiques constitues par des complexes de tc, re ou y comportant des ligands tetraphosphonates et leur preparation

Info

Publication number
FR2636632B1
FR2636632B1 FR8812099A FR8812099A FR2636632B1 FR 2636632 B1 FR2636632 B1 FR 2636632B1 FR 8812099 A FR8812099 A FR 8812099A FR 8812099 A FR8812099 A FR 8812099A FR 2636632 B1 FR2636632 B1 FR 2636632B1
Authority
FR
France
Prior art keywords
tetraphosphonates
complexes
preparation
including letters
radiopharmaceutical products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8812099A
Other languages
English (en)
Other versions
FR2636632A1 (fr
Inventor
Roberto Pasqualini
Michel Vidal
Maurice Vincens
Veronique Comazzi
Henri Mollier
Michele Lecayon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oris Industrie SA
Original Assignee
Oris Industrie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oris Industrie SA filed Critical Oris Industrie SA
Priority to FR8812099A priority Critical patent/FR2636632B1/fr
Priority to PCT/FR1989/000473 priority patent/WO1990002571A1/fr
Publication of FR2636632A1 publication Critical patent/FR2636632A1/fr
Application granted granted Critical
Publication of FR2636632B1 publication Critical patent/FR2636632B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR8812099A 1988-09-16 1988-09-16 Produits radiopharmaceutiques constitues par des complexes de tc, re ou y comportant des ligands tetraphosphonates et leur preparation Expired - Fee Related FR2636632B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR8812099A FR2636632B1 (fr) 1988-09-16 1988-09-16 Produits radiopharmaceutiques constitues par des complexes de tc, re ou y comportant des ligands tetraphosphonates et leur preparation
PCT/FR1989/000473 WO1990002571A1 (fr) 1988-09-16 1989-09-15 Produits radiopharmaceutiques constitues par des complexes tetraphosphonates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8812099A FR2636632B1 (fr) 1988-09-16 1988-09-16 Produits radiopharmaceutiques constitues par des complexes de tc, re ou y comportant des ligands tetraphosphonates et leur preparation

Publications (2)

Publication Number Publication Date
FR2636632A1 FR2636632A1 (fr) 1990-03-23
FR2636632B1 true FR2636632B1 (fr) 1996-02-02

Family

ID=9370067

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8812099A Expired - Fee Related FR2636632B1 (fr) 1988-09-16 1988-09-16 Produits radiopharmaceutiques constitues par des complexes de tc, re ou y comportant des ligands tetraphosphonates et leur preparation

Country Status (2)

Country Link
FR (1) FR2636632B1 (fr)
WO (1) WO1990002571A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT98000B (pt) * 1990-06-18 1998-11-30 Dow Chemical Co Metodo de utilizacao de complexos de acido aminofosfonico como agentes produtores de imagens
EP0538402B1 (fr) * 1990-07-06 2006-03-08 Mallinckrodt Inc. Procede de preparation d'une solution d'un complexe de rhenium radioactif
WO1994026755A1 (fr) * 1993-05-06 1994-11-24 The Dow Chemical Company Complexes d'acides bicyclopolyazamacrocyclophosphoniques, conjugues de ces derniers, procede de preparation associe et d'utilisation en tant que produits radiopharmaceutiques
KR960702470A (ko) * 1993-05-06 1996-04-27 스티븐 에스. 그레이스 콘트라스트제로서 사용하기 위한 비사이클로폴리아자매크로사이클로포스폰산, 그의 착체 및 복합제, 및 이들의 제조방법(bicyclopolyaza-macrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents, and processes for their preparation)
AU2001221607A1 (en) * 2000-11-20 2002-05-27 Ecole Polytechnique Federale De Lausanne (Epfl) Endosseous implant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032625A (en) * 1973-06-11 1977-06-28 Research Corporation Bone-seeking technetium-99m complex
CA1078731A (fr) * 1976-12-16 1980-06-03 Charles E. Frosst And Co. Kit de radiographie des os, utilisant le triethylene tetramine hexa (acide methylenephosphonique)
DE2755874A1 (de) * 1977-12-15 1979-06-21 Hoechst Ag Zinnhaltige markierungsbestecke, verfahren zu ihrer herstellung und praeparate zur skelettdarstellung
US4560548A (en) * 1984-04-10 1985-12-24 The Dow Chemical Company Bone seeking Tc-99m complexes of phosphonate derivatives of bis(aminoalkyl)piperazine
GB8603537D0 (en) * 1986-02-13 1986-03-19 Parker D Conjugate compound

Also Published As

Publication number Publication date
FR2636632A1 (fr) 1990-03-23
WO1990002571A1 (fr) 1990-03-22

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse