CA1076118A - Benzofuranyl derivatives of tetrahydropyridine and piperidine compounds - Google Patents

Benzofuranyl derivatives of tetrahydropyridine and piperidine compounds

Info

Publication number
CA1076118A
CA1076118A CA234,433A CA234433A CA1076118A CA 1076118 A CA1076118 A CA 1076118A CA 234433 A CA234433 A CA 234433A CA 1076118 A CA1076118 A CA 1076118A
Authority
CA
Canada
Prior art keywords
general formula
benzofuranyl
compound
methyl
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA234,433A
Other languages
English (en)
French (fr)
Inventor
Raymond Bernasconi
Karl Schenker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA1076118A publication Critical patent/CA1076118A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA234,433A 1974-08-30 1975-08-28 Benzofuranyl derivatives of tetrahydropyridine and piperidine compounds Expired CA1076118A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1183774A CH605925A5 (pt) 1974-08-30 1974-08-30
CH1511677A CH609980A5 (en) 1974-08-30 1974-08-30 Process for the preparation of novel piperidine derivatives

Publications (1)

Publication Number Publication Date
CA1076118A true CA1076118A (en) 1980-04-22

Family

ID=25709012

Family Applications (1)

Application Number Title Priority Date Filing Date
CA234,433A Expired CA1076118A (en) 1974-08-30 1975-08-28 Benzofuranyl derivatives of tetrahydropyridine and piperidine compounds

Country Status (11)

Country Link
JP (1) JPS5148673A (pt)
AT (1) AT348523B (pt)
AU (1) AU499372B2 (pt)
BE (1) BE832885A (pt)
CA (1) CA1076118A (pt)
CH (2) CH605925A5 (pt)
DE (1) DE2537837A1 (pt)
FR (1) FR2282887A1 (pt)
GB (1) GB1510977A (pt)
NL (1) NL7510142A (pt)
SE (1) SE7508897L (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006524A1 (de) * 1978-06-22 1980-01-09 Ciba-Geigy Ag Neue Tetrahydropyridin- und Piperidinderivate und deren Säureadditionssalze, Verfahren zu deren Herstellung und solche enthaltende pharmazeutische Zusammensetzungen
US4455427A (en) * 1981-07-01 1984-06-19 The Upjohn Company Pyridyl-substituted-benzofurans
US4495357A (en) * 1981-07-01 1985-01-22 The Upjohn Company Pyridyl-substituted-benzofurans
US4490531A (en) * 1981-07-01 1984-12-25 The Upjohn Company Pyridyl-substituted-benzofurans
US4447620A (en) * 1982-06-08 1984-05-08 The Upjohn Company Imidazolyl-substituted benzothiophenes
US4452986A (en) * 1982-06-08 1984-06-05 The Upjohn Company Imidazolyl-substituted benzofurans
US4611059A (en) * 1982-10-12 1986-09-09 The Upjohn Company Pyridyl-substituted benzothiophenes
US4855435A (en) * 1982-10-12 1989-08-08 The Upjohn Company Pyridyl-substituted benzothiophenes
AU579647B2 (en) * 1985-02-21 1988-12-01 Asahi Kasei Kogyo Kabushiki Kaisha Process for adsorption treatment of dissolved fluorine
TW266206B (pt) * 1993-04-28 1995-12-21 Takeda Pharm Industry Co Ltd
DE69701298T2 (de) * 1996-04-15 2000-10-05 Takeda Chemical Industries, Ltd. Hydroxypyridin-Derivate, ihre Herstellung und ihre pharmazeutische Verwendung

Also Published As

Publication number Publication date
FR2282887A1 (fr) 1976-03-26
DE2537837A1 (de) 1976-03-18
AU499372B2 (en) 1979-04-12
AU8435675A (en) 1977-03-03
NL7510142A (nl) 1976-03-02
BE832885A (fr) 1976-03-01
ATA667875A (de) 1978-07-15
AT348523B (de) 1979-02-26
CH605925A5 (pt) 1978-10-13
GB1510977A (en) 1978-05-17
JPS5148673A (pt) 1976-04-26
SE7508897L (sv) 1976-03-01
CH609980A5 (en) 1979-03-30
FR2282887B1 (pt) 1980-04-18

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Legal Events

Date Code Title Description
MKEX Expiry