CA1074802A - L'acide desoxyclavulanique, ses sels et ses esters - Google Patents

L'acide desoxyclavulanique, ses sels et ses esters

Info

Publication number
CA1074802A
CA1074802A CA250,165A CA250165A CA1074802A CA 1074802 A CA1074802 A CA 1074802A CA 250165 A CA250165 A CA 250165A CA 1074802 A CA1074802 A CA 1074802A
Authority
CA
Canada
Prior art keywords
formula
salt
acid
iii
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA250,165A
Other languages
English (en)
Inventor
Thomas T. Howarth
Roger J. Ponsford
Jennifer Goodacre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB15209/75A external-priority patent/GB1545467A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of CA1074802A publication Critical patent/CA1074802A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D503/02—Preparation
    • C07D503/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
CA250,165A 1975-04-14 1976-04-13 L'acide desoxyclavulanique, ses sels et ses esters Expired CA1074802A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB15209/75A GB1545467A (en) 1975-04-14 1975-04-14 Deoxyclavulanic acid and deoxyisoclavulanic acid and derivatives thereof
GB3967175 1975-09-27

Publications (1)

Publication Number Publication Date
CA1074802A true CA1074802A (fr) 1980-04-01

Family

ID=26251136

Family Applications (1)

Application Number Title Priority Date Filing Date
CA250,165A Expired CA1074802A (fr) 1975-04-14 1976-04-13 L'acide desoxyclavulanique, ses sels et ses esters

Country Status (22)

Country Link
JP (1) JPS51127093A (fr)
AR (1) AR208773A1 (fr)
AT (1) AT342199B (fr)
AU (1) AU497577B2 (fr)
CA (1) CA1074802A (fr)
CH (1) CH602742A5 (fr)
DE (1) DE2616088A1 (fr)
DK (1) DK144066C (fr)
ES (1) ES446468A1 (fr)
FI (1) FI760946A (fr)
FR (1) FR2336130A1 (fr)
GR (1) GR58256B (fr)
HU (1) HU175444B (fr)
IE (1) IE42666B1 (fr)
IL (1) IL49279A (fr)
LU (1) LU74749A1 (fr)
MX (1) MX3453E (fr)
NL (1) NL7603840A (fr)
NO (1) NO761241L (fr)
PT (1) PT64897B (fr)
SE (1) SE427037B (fr)
YU (1) YU69476A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5359690A (en) * 1976-09-09 1978-05-29 Glaxo Lab Ltd Production of novel betaa lactam
AT363181B (de) * 1976-10-25 1981-07-10 Glaxo Lab Ltd Verfahren zur herstellung von neuen clavulansaeurederivaten
GB9007143D0 (en) * 1990-03-30 1990-05-30 Beecham Group Plc Veterinary composition

Also Published As

Publication number Publication date
ES446468A1 (es) 1977-11-01
FR2336130B1 (fr) 1979-06-22
IE42666L (en) 1976-10-14
LU74749A1 (fr) 1976-11-11
AT342199B (de) 1978-03-28
CH602742A5 (fr) 1978-07-31
SE427037B (sv) 1983-02-28
YU69476A (en) 1982-05-31
MX3453E (es) 1980-12-03
SE7604287L (sv) 1976-10-15
NO761241L (fr) 1976-10-15
FR2336130A1 (fr) 1977-07-22
PT64897A (en) 1976-04-01
DK156576A (da) 1976-10-15
AU497577B2 (en) 1978-12-21
IL49279A0 (en) 1976-06-30
DK144066C (da) 1982-05-10
AU1302076A (en) 1977-10-20
JPS51127093A (en) 1976-11-05
NL7603840A (nl) 1976-10-18
IL49279A (en) 1979-05-31
FI760946A (fr) 1976-10-15
HU175444B (hu) 1980-08-28
GR58256B (en) 1977-09-15
PT64897B (en) 1977-08-18
DK144066B (da) 1981-11-30
DE2616088A1 (de) 1976-10-28
ATA215576A (de) 1977-07-15
IE42666B1 (en) 1980-09-24
AR208773A1 (es) 1977-02-28

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Legal Events

Date Code Title Description
MKEX Expiry