CA1072969A - Hypolipidemic p-aminobenzoic acids - Google Patents

Hypolipidemic p-aminobenzoic acids

Info

Publication number
CA1072969A
CA1072969A CA269,483A CA269483A CA1072969A CA 1072969 A CA1072969 A CA 1072969A CA 269483 A CA269483 A CA 269483A CA 1072969 A CA1072969 A CA 1072969A
Authority
CA
Canada
Prior art keywords
compound
benzodioxol
benzoic acid
hypolipidemic
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA269,483A
Other languages
English (en)
French (fr)
Inventor
Eugene R. Wagner
Bobbie J. Allen
Alfred A. Renzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Application granted granted Critical
Publication of CA1072969A publication Critical patent/CA1072969A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
CA269,483A 1976-01-19 1977-01-11 Hypolipidemic p-aminobenzoic acids Expired CA1072969A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65009076A 1976-01-19 1976-01-19

Publications (1)

Publication Number Publication Date
CA1072969A true CA1072969A (en) 1980-03-04

Family

ID=24607411

Family Applications (1)

Application Number Title Priority Date Filing Date
CA269,483A Expired CA1072969A (en) 1976-01-19 1977-01-11 Hypolipidemic p-aminobenzoic acids

Country Status (14)

Country Link
JP (1) JPS5289660A (enrdf_load_html_response)
AT (1) AT347923B (enrdf_load_html_response)
AU (1) AU500881B2 (enrdf_load_html_response)
BE (1) BE850516A (enrdf_load_html_response)
CA (1) CA1072969A (enrdf_load_html_response)
CH (1) CH628340A5 (enrdf_load_html_response)
DE (1) DE2702058C2 (enrdf_load_html_response)
DK (1) DK153471C (enrdf_load_html_response)
FR (1) FR2338040A1 (enrdf_load_html_response)
GB (2) GB1521459A (enrdf_load_html_response)
IE (1) IE44858B1 (enrdf_load_html_response)
NL (1) NL7700480A (enrdf_load_html_response)
NO (1) NO145839C (enrdf_load_html_response)
SE (1) SE435175B (enrdf_load_html_response)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE716668C (de) * 1938-02-15 1942-01-27 Dr Aladar Skita Verfahren zur Herstellung von Derivaten substituierter Aminobenzoesaeuren
FR2080069A5 (enrdf_load_html_response) * 1970-02-23 1971-11-12 Commissariat Energie Atomique
US3868416A (en) * 1973-10-01 1975-02-25 American Cyanamid Co Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives

Also Published As

Publication number Publication date
SE7700490L (sv) 1977-07-20
BE850516A (fr) 1977-07-19
DK153471B (da) 1988-07-18
DE2702058C2 (de) 1985-09-19
AU500881B2 (en) 1979-06-07
DK153471C (da) 1988-11-21
GB1521459A (en) 1978-08-16
NL7700480A (nl) 1977-07-21
NO145839B (no) 1982-03-01
SE435175B (sv) 1984-09-10
FR2338040B1 (enrdf_load_html_response) 1980-04-30
FR2338040A1 (fr) 1977-08-12
JPS6233230B2 (enrdf_load_html_response) 1987-07-20
ATA31277A (de) 1978-06-15
AT347923B (de) 1979-01-25
AU2114077A (en) 1978-07-13
IE44858B1 (en) 1982-04-21
CH628340A5 (en) 1982-02-26
DK8177A (da) 1977-07-20
NO770151L (no) 1977-07-20
IE44858L (en) 1977-07-19
DE2702058A1 (de) 1977-07-28
NO145839C (no) 1982-06-09
JPS5289660A (en) 1977-07-27
GB1521458A (en) 1978-08-16

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Legal Events

Date Code Title Description
MKEX Expiry