CA1068694A - Process for preparing 2(1h)-quinazolinone derivatives - Google Patents
Process for preparing 2(1h)-quinazolinone derivativesInfo
- Publication number
- CA1068694A CA1068694A CA267,562A CA267562A CA1068694A CA 1068694 A CA1068694 A CA 1068694A CA 267562 A CA267562 A CA 267562A CA 1068694 A CA1068694 A CA 1068694A
- Authority
- CA
- Canada
- Prior art keywords
- phenyl
- methyl
- methoxy
- quinazolinone
- sulfur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
- C07D239/82—Oxygen atoms with an aryl radical attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50148279A JPS5271483A (en) | 1975-12-11 | 1975-12-11 | Synthesis of 2(1h)-quinazolinone derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1068694A true CA1068694A (en) | 1979-12-25 |
Family
ID=15449201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA267,562A Expired CA1068694A (en) | 1975-12-11 | 1976-12-09 | Process for preparing 2(1h)-quinazolinone derivatives |
Country Status (13)
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT374469B (de) * | 1978-12-07 | 1984-04-25 | Ortho Pharma Corp | Verfahren zur herstellung von neuen substituierten chinazolinen und ihren salzen |
US4617392A (en) * | 1983-09-29 | 1986-10-14 | Ortho Pharmaceutical Corporation | 4-alkyl-5,6-methylenedioxy-2-1[H]-quinazolinones useful as cardiotonic agents |
US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
AR038658A1 (es) * | 2001-06-15 | 2005-01-26 | Novartis Ag | Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento |
EP1394242A3 (en) * | 2002-08-07 | 2004-04-21 | Rohm And Haas Company | Cyclic thioureas and their use as additives for lubricating oils |
GB0230015D0 (en) * | 2002-12-23 | 2003-01-29 | Novartis Ag | Organic compounds |
AU2007231842B2 (en) * | 2002-12-23 | 2011-04-14 | Novartis Ag | Derivatives of aryl-quinazoline/aryl-2-amino-phenyl methanone which promote the release of parathyroid hormone |
JP4533391B2 (ja) * | 2004-01-16 | 2010-09-01 | エフ.ホフマン−ラ ロシュ アーゲー | 中枢神経系疾患の処置のための5−ヒドロキシトリプタミンレセプター(5−ht)のモジュレーターとしての、1−ベンジル−5−ピペラジン−1−イル−3,4−ジヒドロ−1h−キナゾリン−2−オン誘導体、ならびにそれぞれの1h−ベンゾ(1,2,6)チアジアジン−2,2−ジオキシドおよび1,4−ジヒドロベンゾ(d)(1,3)オキサジン−2−オン誘導体 |
US8058469B2 (en) * | 2008-11-03 | 2011-11-15 | Sabic Innovative Plastics Ip B.V. | Method for making carbamates, ureas and isocyanates |
US9834525B2 (en) | 2014-02-04 | 2017-12-05 | University Of Tennessee Research Foundation | Inhibitors of paxillin function and related compositions and methods |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE93775C (US20080094685A1-20080424-C00004.png) * | ||||
US3560501A (en) * | 1966-09-15 | 1971-02-02 | Ciba Geigy Corp | Process for making dihydroquinazolines |
US3509149A (en) * | 1968-05-10 | 1970-04-28 | Searle & Co | Aryl and aralkyl 3,4-dihydro-2-(1h)-quinazolinones |
CH522673A (de) * | 1969-11-27 | 1972-05-15 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen Diglycidylderivaten N-heterocyclischer Verbindungen, und ihre Anwendung |
US3748331A (en) * | 1971-05-06 | 1973-07-24 | Sandoz Ag | 1,4-disubstituted-methylenedioxy -2-(1h)-quinazolinones and quinazolinthiones |
BE785937A (fr) * | 1971-07-08 | 1973-01-08 | Sandoz Sa | Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments |
US3937705A (en) * | 1972-03-09 | 1976-02-10 | Sandoz, Inc. | 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone |
JPS5251379A (en) * | 1975-10-24 | 1977-04-25 | Sumitomo Chem Co Ltd | Preparation 3,4-dihydro-2(1h)-quinazoline derivates |
JPS5291885A (en) * | 1976-01-23 | 1977-08-02 | Sumitomo Chem Co Ltd | 3,4-dihydro-2(1h)-quinazolinone derivatives |
-
1975
- 1975-12-11 JP JP50148279A patent/JPS5271483A/ja active Pending
-
1976
- 1976-11-30 NL NL7613307A patent/NL7613307A/xx not_active Application Discontinuation
- 1976-12-06 US US05/748,145 patent/US4387223A/en not_active Expired - Lifetime
- 1976-12-06 GB GB50824/76A patent/GB1510270A/en not_active Expired
- 1976-12-07 FR FR7636740A patent/FR2376142A1/fr active Granted
- 1976-12-08 HU HU76SU934A patent/HU173530B/hu unknown
- 1976-12-09 CA CA267,562A patent/CA1068694A/en not_active Expired
- 1976-12-09 CH CH1550576A patent/CH602667A5/xx not_active IP Right Cessation
- 1976-12-09 SE SE7613839A patent/SE422578B/xx unknown
- 1976-12-09 DK DK553076AA patent/DK138989B/da unknown
- 1976-12-10 AT AT915976A patent/AT352737B/de not_active IP Right Cessation
- 1976-12-10 DE DE19762656156 patent/DE2656156A1/de not_active Withdrawn
- 1976-12-10 MX MX765213U patent/MX3930E/es unknown
Also Published As
Publication number | Publication date |
---|---|
SE7613839L (sv) | 1977-06-12 |
FR2376142B1 (US20080094685A1-20080424-C00004.png) | 1979-04-20 |
DK553076A (US20080094685A1-20080424-C00004.png) | 1977-06-12 |
SE422578B (sv) | 1982-03-15 |
NL7613307A (nl) | 1977-06-14 |
ATA915976A (de) | 1979-03-15 |
GB1510270A (en) | 1978-05-10 |
DK138989C (US20080094685A1-20080424-C00004.png) | 1979-05-14 |
DK138989B (da) | 1978-11-27 |
FR2376142A1 (fr) | 1978-07-28 |
HU173530B (hu) | 1979-06-28 |
US4387223A (en) | 1983-06-07 |
AT352737B (de) | 1979-10-10 |
DE2656156A1 (de) | 1977-06-23 |
MX3930E (es) | 1981-10-01 |
JPS5271483A (en) | 1977-06-14 |
AU2016476A (en) | 1977-11-10 |
CH602667A5 (US20080094685A1-20080424-C00004.png) | 1978-07-31 |
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