CA1061731A - Aminocyclitol antibiotics and processes therefor - Google Patents

Aminocyclitol antibiotics and processes therefor

Info

Publication number
CA1061731A
CA1061731A CA245,916A CA245916A CA1061731A CA 1061731 A CA1061731 A CA 1061731A CA 245916 A CA245916 A CA 245916A CA 1061731 A CA1061731 A CA 1061731A
Authority
CA
Canada
Prior art keywords
methyl
formula
hydroxy
methylamino
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA245,916A
Other languages
English (en)
French (fr)
Inventor
Sol J. Daum
Robert L. Clarke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/550,273 external-priority patent/US3972930A/en
Priority claimed from US05/615,593 external-priority patent/US3982996A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Application granted granted Critical
Publication of CA1061731A publication Critical patent/CA1061731A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/487Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/497Saturated compounds containing a keto group being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA245,916A 1975-02-18 1976-02-17 Aminocyclitol antibiotics and processes therefor Expired CA1061731A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/550,273 US3972930A (en) 1975-02-18 1975-02-18 Aminocyclitol antibiotics
US05/615,593 US3982996A (en) 1975-09-22 1975-09-22 Process for preparing aminocyclitol antibiotics

Publications (1)

Publication Number Publication Date
CA1061731A true CA1061731A (en) 1979-09-04

Family

ID=27069389

Family Applications (1)

Application Number Title Priority Date Filing Date
CA245,916A Expired CA1061731A (en) 1975-02-18 1976-02-17 Aminocyclitol antibiotics and processes therefor

Country Status (21)

Country Link
JP (1) JPS51108041A (US20110158925A1-20110630-C00042.png)
AR (3) AR221027A1 (US20110158925A1-20110630-C00042.png)
AU (1) AU503105B2 (US20110158925A1-20110630-C00042.png)
CA (1) CA1061731A (US20110158925A1-20110630-C00042.png)
CH (3) CH617964A5 (US20110158925A1-20110630-C00042.png)
DE (1) DE2606517A1 (US20110158925A1-20110630-C00042.png)
DK (1) DK143111C (US20110158925A1-20110630-C00042.png)
EG (1) EG12994A (US20110158925A1-20110630-C00042.png)
ES (1) ES445274A1 (US20110158925A1-20110630-C00042.png)
FI (1) FI56026C (US20110158925A1-20110630-C00042.png)
FR (1) FR2301265A1 (US20110158925A1-20110630-C00042.png)
GB (1) GB1529376A (US20110158925A1-20110630-C00042.png)
GR (1) GR60050B (US20110158925A1-20110630-C00042.png)
IE (1) IE42807B1 (US20110158925A1-20110630-C00042.png)
IL (1) IL49053A (US20110158925A1-20110630-C00042.png)
IN (2) IN147046B (US20110158925A1-20110630-C00042.png)
NL (1) NL7601655A (US20110158925A1-20110630-C00042.png)
NO (3) NO147308C (US20110158925A1-20110630-C00042.png)
NZ (1) NZ180036A (US20110158925A1-20110630-C00042.png)
PT (1) PT64816B (US20110158925A1-20110630-C00042.png)
SE (2) SE7601810L (US20110158925A1-20110630-C00042.png)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE476970A (US20110158925A1-20110630-C00042.png) * 1946-10-24
WO2007142150A1 (ja) 2006-06-02 2007-12-13 Meiji Seika Kaisha, Ltd. 新規アミノグリコシド系抗生物質

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606434A5 (US20110158925A1-20110630-C00042.png) * 1973-08-06 1978-10-31 Scherico Ltd

Also Published As

Publication number Publication date
FI56026C (fi) 1979-11-12
AU503105B2 (en) 1979-08-23
AR227266A1 (es) 1982-10-15
AR217417A1 (es) 1980-03-31
DK63176A (da) 1976-08-19
NO760472L (US20110158925A1-20110630-C00042.png) 1976-08-19
AU1117776A (en) 1977-08-25
DK143111C (da) 1981-11-16
IN149240B (US20110158925A1-20110630-C00042.png) 1981-10-10
FI56026B (fi) 1979-07-31
PT64816A (en) 1976-03-01
PT64816B (en) 1978-07-03
FR2301265B1 (US20110158925A1-20110630-C00042.png) 1979-05-25
IN147046B (US20110158925A1-20110630-C00042.png) 1979-10-27
CH617964A5 (en) 1980-06-30
CH618214A5 (en) 1980-07-15
DE2606517A1 (de) 1976-08-26
GR60050B (en) 1978-04-04
NO146811C (no) 1982-12-15
EG12994A (en) 1980-07-31
IL49053A0 (en) 1976-04-30
GB1529376A (en) 1978-10-18
SE8007540L (sv) 1980-10-27
NO820574L (no) 1976-08-19
NO147308C (no) 1983-03-16
ES445274A1 (es) 1977-06-16
IE42807B1 (en) 1980-10-22
AR221027A1 (es) 1980-12-30
CH618215A5 (en) 1980-07-15
SE7601810L (sv) 1976-08-19
IL49053A (en) 1979-11-30
JPS51108041A (US20110158925A1-20110630-C00042.png) 1976-09-25
NL7601655A (nl) 1976-08-20
NO147308B (no) 1982-12-06
IE42807L (en) 1976-08-18
NO146811B (no) 1982-09-06
NZ180036A (en) 1979-10-25
FI760387A (US20110158925A1-20110630-C00042.png) 1976-08-19
NO803185L (no) 1976-08-19
NO148298C (no) 1983-09-14
FR2301265A1 (fr) 1976-09-17
DK143111B (da) 1981-03-30
NO148298B (no) 1983-06-06

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