CA1055498A - 2,4-diamino-5-benzylpyrimidines, process for their preparation and pharmaceutical compositions containing these compounds - Google Patents

2,4-diamino-5-benzylpyrimidines, process for their preparation and pharmaceutical compositions containing these compounds

Info

Publication number
CA1055498A
CA1055498A CA262,152A CA262152A CA1055498A CA 1055498 A CA1055498 A CA 1055498A CA 262152 A CA262152 A CA 262152A CA 1055498 A CA1055498 A CA 1055498A
Authority
CA
Canada
Prior art keywords
acid
diamino
benzylpyrimidine
chemical equivalent
obvious chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA262,152A
Other languages
English (en)
French (fr)
Inventor
Walter Liebenow
Jaroslav Prikryl
Edgar Fritschi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heumann Ludwig and Co GmbH
Original Assignee
Heumann Ludwig and Co GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Ludwig and Co GmbH filed Critical Heumann Ludwig and Co GmbH
Application granted granted Critical
Publication of CA1055498A publication Critical patent/CA1055498A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA262,152A 1975-10-17 1976-09-27 2,4-diamino-5-benzylpyrimidines, process for their preparation and pharmaceutical compositions containing these compounds Expired CA1055498A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2546667A DE2546667C3 (de) 1975-10-17 1975-10-17 2,4-DiamüH»-5-(3-methoxy-4-hydroxy-5-halogenbenzyl)-pyrimidine, und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CA1055498A true CA1055498A (en) 1979-05-29

Family

ID=5959437

Family Applications (1)

Application Number Title Priority Date Filing Date
CA262,152A Expired CA1055498A (en) 1975-10-17 1976-09-27 2,4-diamino-5-benzylpyrimidines, process for their preparation and pharmaceutical compositions containing these compounds

Country Status (17)

Country Link
JP (1) JPS5251376A (xx)
AR (1) AR210905A1 (xx)
AT (1) AT352735B (xx)
AU (1) AU1724576A (xx)
BE (1) BE846397A (xx)
CA (1) CA1055498A (xx)
CH (1) CH623313A5 (xx)
DE (1) DE2546667C3 (xx)
ES (1) ES451375A1 (xx)
FR (1) FR2327786A1 (xx)
GB (1) GB1522537A (xx)
GR (1) GR60352B (xx)
HU (1) HU174155B (xx)
IL (1) IL50430A0 (xx)
MX (1) MX4485E (xx)
NL (1) NL7609652A (xx)
PT (1) PT65482B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2720771C3 (de) 1977-05-09 1979-11-29 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-Diamino-5-(33-dimethoxy-4thioalkyl-benzyD-pyrimidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
MA18450A1 (fr) * 1978-05-24 1979-12-31 Wellcome Found Composition de benzylpirimidines
HU188588B (en) * 1982-08-13 1986-04-28 Egyt Gyogyszervegyeszeti Gyar Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives

Also Published As

Publication number Publication date
GB1522537A (en) 1978-08-23
GR60352B (en) 1978-05-18
FR2327786A1 (fr) 1977-05-13
AT352735B (de) 1979-10-10
DE2546667A1 (de) 1977-04-28
PT65482A (de) 1976-09-01
FR2327786B1 (xx) 1980-04-18
PT65482B (de) 1978-02-13
HU174155B (hu) 1979-11-28
ES451375A1 (es) 1981-10-16
AU1724576A (en) 1978-03-02
BE846397A (fr) 1977-01-17
DE2546667C3 (de) 1978-10-12
DE2546667B2 (de) 1978-02-09
MX4485E (es) 1982-05-21
AR210905A1 (es) 1977-09-30
CH623313A5 (en) 1981-05-29
ATA649276A (de) 1979-03-15
IL50430A0 (en) 1976-11-30
JPS5251376A (en) 1977-04-25
NL7609652A (nl) 1977-04-19

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