CA1055027A - Basically substituted 3,4-dihydro-2h-isoquinolin-1-thiones and process for preparing them - Google Patents

Basically substituted 3,4-dihydro-2h-isoquinolin-1-thiones and process for preparing them

Info

Publication number
CA1055027A
CA1055027A CA233,696A CA233696A CA1055027A CA 1055027 A CA1055027 A CA 1055027A CA 233696 A CA233696 A CA 233696A CA 1055027 A CA1055027 A CA 1055027A
Authority
CA
Canada
Prior art keywords
formula
dihydro
acid
compound
defined above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA233,696A
Other languages
English (en)
French (fr)
Inventor
Rudolf Kunstmann
Joachim Kaiser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1055027A publication Critical patent/CA1055027A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CA233,696A 1974-08-14 1975-08-13 Basically substituted 3,4-dihydro-2h-isoquinolin-1-thiones and process for preparing them Expired CA1055027A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19742438966 DE2438966A1 (de) 1974-08-14 1974-08-14 Basisch substituierte 3,,4-dihydro2h-isochinolin-1-one und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CA1055027A true CA1055027A (en) 1979-05-22

Family

ID=5923161

Family Applications (1)

Application Number Title Priority Date Filing Date
CA233,696A Expired CA1055027A (en) 1974-08-14 1975-08-13 Basically substituted 3,4-dihydro-2h-isoquinolin-1-thiones and process for preparing them

Country Status (11)

Country Link
JP (1) JPS5143767A (fi)
AT (1) AT349019B (fi)
BE (1) BE832470A (fi)
CA (1) CA1055027A (fi)
DE (1) DE2438966A1 (fi)
DK (1) DK367175A (fi)
FR (1) FR2281763A1 (fi)
GB (1) GB1516535A (fi)
IE (1) IE41512B1 (fi)
LU (1) LU73197A1 (fi)
NL (1) NL7509486A (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58203968A (ja) * 1982-05-21 1983-11-28 Otsuka Pharmaceut Co Ltd イソカルボスチリル誘導体
US8404896B2 (en) * 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2143744A1 (de) * 1971-09-01 1973-03-08 Hoechst Ag 3,4-dihydro-2h-isochinolin-1-one und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DE2438966A1 (de) 1976-03-04
NL7509486A (nl) 1976-02-17
ATA629775A (de) 1978-08-15
DK367175A (da) 1976-02-15
FR2281763A1 (fr) 1976-03-12
JPS5143767A (en) 1976-04-14
BE832470A (fr) 1976-02-16
IE41512L (en) 1976-02-14
IE41512B1 (en) 1980-01-16
FR2281763B1 (fi) 1978-09-01
LU73197A1 (fi) 1977-04-13
GB1516535A (en) 1978-07-05
AT349019B (de) 1979-03-12

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