IE41512L - 3, 4 - dihydro - 2h - isoquinolin - 1 - ones - Google Patents

3, 4 - dihydro - 2h - isoquinolin - 1 - ones

Info

Publication number
IE41512L
IE41512L IE180275A IE180275A IE41512L IE 41512 L IE41512 L IE 41512L IE 180275 A IE180275 A IE 180275A IE 180275 A IE180275 A IE 180275A IE 41512 L IE41512 L IE 41512L
Authority
IE
Ireland
Prior art keywords
chained
branched
radical
hydrogen
substituted
Prior art date
Application number
IE180275A
Other versions
IE41512B1 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE41512L publication Critical patent/IE41512L/en
Publication of IE41512B1 publication Critical patent/IE41512B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

this invention relates to 3,4-aihydro-2H-isoquinoline-l-ones of the formula (X) wherein X1 represents hydrogen, a saturated or unsaturated, sraight-chained or branched alkyl radical having 1 to 6 carbon atoms or the phenyl radical, R2 represents a dialkylaminoalkyl radical of the formula wherein A represents a straight-chained or branched low molecular alkylene group and R5 and R6 are identical or different and represent straight-chained or branched, low molecular alkyl radicals and may form together with the nitrogen atom a 5-, 6or 7-membered ring, wherein one of the hydrocarbons is substituted by a hetero atom which may be substituted with hydrogen, C1-C4 alkyl or the phenyl radical, R3 and R4 are identical or different and represent hydrogen or a lower alkoxy group having 1 to 4 carbon atoms, and the physiologically tolerable salts thereof. The compounds have an antiarrhythmic activity and are suitable for treating disturbances of cardiac rhythm. [CA1055027A]
IE180275A 1974-08-14 1975-08-13 3,4-dihydro-2h-isoquinoline-1-ones and process for preparing them IE41512B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19742438966 DE2438966A1 (en) 1974-08-14 1974-08-14 BASIC SUBSTITUTES 3, 4-DIHYDRO2H-ISOCHINOLIN-1-ONE AND THE PROCESS FOR THEIR PRODUCTION

Publications (2)

Publication Number Publication Date
IE41512L true IE41512L (en) 1976-02-14
IE41512B1 IE41512B1 (en) 1980-01-16

Family

ID=5923161

Family Applications (1)

Application Number Title Priority Date Filing Date
IE180275A IE41512B1 (en) 1974-08-14 1975-08-13 3,4-dihydro-2h-isoquinoline-1-ones and process for preparing them

Country Status (11)

Country Link
JP (1) JPS5143767A (en)
AT (1) AT349019B (en)
BE (1) BE832470A (en)
CA (1) CA1055027A (en)
DE (1) DE2438966A1 (en)
DK (1) DK367175A (en)
FR (1) FR2281763A1 (en)
GB (1) GB1516535A (en)
IE (1) IE41512B1 (en)
LU (1) LU73197A1 (en)
NL (1) NL7509486A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58203968A (en) * 1982-05-21 1983-11-28 Otsuka Pharmaceut Co Ltd Isocarbostyryl derivative
ATE547394T1 (en) * 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-BENZYL)-2,2-(BIS-PHENYL)-PROPANE-1- AMINE DERIVATIVES AS CETP INHIBITORS FOR THE TREATMENT OF ATHEROSCLERosis AND CARDIOVASCULAR DISEASES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2143744A1 (en) * 1971-09-01 1973-03-08 Hoechst Ag 3,4-DIHYDRO-2H-ISOCHINOLIN-1-ONE AND THE METHOD FOR MANUFACTURING IT

Also Published As

Publication number Publication date
CA1055027A (en) 1979-05-22
AT349019B (en) 1979-03-12
FR2281763B1 (en) 1978-09-01
BE832470A (en) 1976-02-16
IE41512B1 (en) 1980-01-16
DK367175A (en) 1976-02-15
JPS5143767A (en) 1976-04-14
DE2438966A1 (en) 1976-03-04
GB1516535A (en) 1978-07-05
FR2281763A1 (en) 1976-03-12
LU73197A1 (en) 1977-04-13
NL7509486A (en) 1976-02-17
ATA629775A (en) 1978-08-15

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