CA1046057A - 1-N-(.alpha.-HYDROXY-.beta.-AMINOPROPIONYL) XK-62-2 AND METHOD OF PRODUCTION THEREOF - Google Patents

1-N-(.alpha.-HYDROXY-.beta.-AMINOPROPIONYL) XK-62-2 AND METHOD OF PRODUCTION THEREOF

Info

Publication number
CA1046057A
CA1046057A CA221,422A CA221422A CA1046057A CA 1046057 A CA1046057 A CA 1046057A CA 221422 A CA221422 A CA 221422A CA 1046057 A CA1046057 A CA 1046057A
Authority
CA
Canada
Prior art keywords
group
hydroxy
compound
protecting
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA221,422A
Other languages
English (en)
French (fr)
Inventor
Shinji Tomioka
Yasuki Mori
Kunikatsu Shirahata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of CA1046057A publication Critical patent/CA1046057A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA221,422A 1974-03-07 1975-03-06 1-N-(.alpha.-HYDROXY-.beta.-AMINOPROPIONYL) XK-62-2 AND METHOD OF PRODUCTION THEREOF Expired CA1046057A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2575374A JPS573679B2 (cs) 1974-03-07 1974-03-07

Publications (1)

Publication Number Publication Date
CA1046057A true CA1046057A (en) 1979-01-09

Family

ID=12174581

Family Applications (1)

Application Number Title Priority Date Filing Date
CA221,422A Expired CA1046057A (en) 1974-03-07 1975-03-06 1-N-(.alpha.-HYDROXY-.beta.-AMINOPROPIONYL) XK-62-2 AND METHOD OF PRODUCTION THEREOF

Country Status (14)

Country Link
JP (1) JPS573679B2 (cs)
AT (1) AT340588B (cs)
CA (1) CA1046057A (cs)
CH (1) CH613710A5 (cs)
DE (1) DE2509885C3 (cs)
DK (1) DK88475A (cs)
ES (1) ES435375A1 (cs)
FR (1) FR2263251B1 (cs)
GB (1) GB1500218A (cs)
NL (1) NL7502740A (cs)
NO (1) NO140428C (cs)
PH (1) PH13670A (cs)
SE (1) SE416208B (cs)
ZA (1) ZA751414B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136254A (en) * 1976-06-17 1979-01-23 Schering Corporation Process of selectively blocking amino functions in aminoglycosides using transition metal salts and intermediates used thereby
EP0000057B1 (de) * 1977-06-10 1982-07-14 Bayer Ag Selektiv geschützte 4,6-Di-O-(aminoglycosyl)-1,3-diaminocyclitole

Also Published As

Publication number Publication date
AT340588B (de) 1977-12-27
SE416208B (sv) 1980-12-08
CH613710A5 (en) 1979-10-15
ES435375A1 (es) 1977-05-01
NO140428C (no) 1979-08-29
GB1500218A (en) 1978-02-08
ZA751414B (en) 1976-10-27
ATA173875A (de) 1977-04-15
DK88475A (cs) 1975-09-08
DE2509885C3 (de) 1978-08-17
NL7502740A (nl) 1975-09-09
DE2509885A1 (de) 1975-09-11
NO750720L (cs) 1975-09-09
NO140428B (no) 1979-05-21
FR2263251A1 (cs) 1975-10-03
JPS50117748A (cs) 1975-09-16
PH13670A (en) 1980-08-26
DE2509885B2 (de) 1977-12-08
JPS573679B2 (cs) 1982-01-22
FR2263251B1 (cs) 1977-07-22

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