CA1041544A - 2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3(tertbutylamino)-propoxy)-2,3-naphtalenediols - Google Patents

2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3(tertbutylamino)-propoxy)-2,3-naphtalenediols

Info

Publication number
CA1041544A
CA1041544A CA198,374A CA198374A CA1041544A CA 1041544 A CA1041544 A CA 1041544A CA 198374 A CA198374 A CA 198374A CA 1041544 A CA1041544 A CA 1041544A
Authority
CA
Canada
Prior art keywords
tert
tetrahydro
cis
tartaric acid
butylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA198,374A
Other languages
English (en)
Inventor
Frederic P. Hauck
Joseph E. Sundeen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Priority to CA305,559A priority Critical patent/CA1059147A/fr
Priority to CA305,558A priority patent/CA1064965A/fr
Application granted granted Critical
Publication of CA1041544A publication Critical patent/CA1041544A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA198,374A 1973-05-03 1974-04-29 2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3(tertbutylamino)-propoxy)-2,3-naphtalenediols Expired CA1041544A (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA305,559A CA1059147A (fr) 1973-05-03 1978-06-15 Derives 2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3-(tertbutylamino)-propoxy)-2,3-naphtalenediols
CA305,558A CA1064965A (fr) 1973-05-03 1978-06-15 2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3-(tert-butylamino)-propoxy)-2,3-naphthalenediols optiquement actifs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35705873A 1973-05-03 1973-05-03
US35705973A 1973-05-03 1973-05-03

Publications (1)

Publication Number Publication Date
CA1041544A true CA1041544A (fr) 1978-10-31

Family

ID=26999501

Family Applications (1)

Application Number Title Priority Date Filing Date
CA198,374A Expired CA1041544A (fr) 1973-05-03 1974-04-29 2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3(tertbutylamino)-propoxy)-2,3-naphtalenediols

Country Status (5)

Country Link
JP (1) JPS5018449A (fr)
CA (1) CA1041544A (fr)
DE (1) DE2421549A1 (fr)
FR (1) FR2236489B1 (fr)
GB (1) GB1464950A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5319141A (en) * 1989-09-25 1994-06-07 Acic (Canada) Inc. Process of making nadolol

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5844899Y2 (ja) * 1978-09-30 1983-10-12 新東工業株式会社 竪型無枠式鋳型造型機
AU2297192A (en) * 1991-06-28 1993-01-25 Sepracor, Inc. Optically pure s(-) nadolol for treatment of cardiovascular disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE755071A (fr) * 1969-09-17 1971-02-22 Warner Lambert Pharmaceutical Procede de resolution de la dl-5-/3-(terbutylamino)-2- hydroxy-propoxy/-3,4-dihydro-1(2h) naphtalenone

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5319141A (en) * 1989-09-25 1994-06-07 Acic (Canada) Inc. Process of making nadolol

Also Published As

Publication number Publication date
JPS5018449A (fr) 1975-02-26
FR2236489B1 (fr) 1978-07-28
FR2236489A1 (fr) 1975-02-07
GB1464950A (en) 1977-02-16
DE2421549A1 (de) 1974-11-21

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