CA1039731A - Process for preparing new 2-methoxy-benzamide derivatives - Google Patents

Process for preparing new 2-methoxy-benzamide derivatives

Info

Publication number
CA1039731A
CA1039731A CA241,723A CA241723A CA1039731A CA 1039731 A CA1039731 A CA 1039731A CA 241723 A CA241723 A CA 241723A CA 1039731 A CA1039731 A CA 1039731A
Authority
CA
Canada
Prior art keywords
formula
alkyl
process according
carbon atoms
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA241,723A
Other languages
English (en)
French (fr)
Inventor
Henry Najer
Don P.R.L. Giudicelli
Maurice Jalfre
Daniel C.L. Obitz
Philippe M.J. Manoury
Jean-Pierre Kaplan
Bernard M. Raizon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7441718A external-priority patent/FR2294698A1/fr
Priority claimed from FR7531334A external-priority patent/FR2327771A2/fr
Priority claimed from FR7534570A external-priority patent/FR2331345A2/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of CA1039731A publication Critical patent/CA1039731A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA241,723A 1974-12-18 1975-12-15 Process for preparing new 2-methoxy-benzamide derivatives Expired CA1039731A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7441718A FR2294698A1 (fr) 1974-12-18 1974-12-18 Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
FR7531334A FR2327771A2 (fr) 1975-10-14 1975-10-14 Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
FR7534570A FR2331345A2 (fr) 1975-11-13 1975-11-13 Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment

Publications (1)

Publication Number Publication Date
CA1039731A true CA1039731A (en) 1978-10-03

Family

ID=27250393

Family Applications (1)

Application Number Title Priority Date Filing Date
CA241,723A Expired CA1039731A (en) 1974-12-18 1975-12-15 Process for preparing new 2-methoxy-benzamide derivatives

Country Status (17)

Country Link
AT (1) AT353782B (xx)
AU (1) AU497616B2 (xx)
CA (1) CA1039731A (xx)
CH (1) CH612668A5 (xx)
DE (1) DE2556457C3 (xx)
DK (1) DK574075A (xx)
ES (2) ES443563A1 (xx)
FI (1) FI753586A (xx)
GB (1) GB1508880A (xx)
GR (1) GR59205B (xx)
IE (1) IE42210B1 (xx)
IL (1) IL48678A (xx)
LU (1) LU74026A1 (xx)
MX (1) MX3180E (xx)
NL (1) NL168219C (xx)
NO (1) NO143625C (xx)
SE (1) SE412908B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189495A (en) * 1974-09-17 1980-02-19 Synthelabo 2-Methoxy-benzamide derivatives
US4097481A (en) * 1976-11-08 1978-06-27 Riker Laboratories, Inc. Tertiary amide derivatives of pyrrolidine and piperidine
FR2415099A1 (fr) * 1978-01-20 1979-08-17 Ile De France Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes
FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
SE411118B (sv) * 1978-03-23 1979-12-03 Astra Laekemedel Ab Ett forfarande for framstellning av 2,6-dialkoxibensamider med terapentiska egenskaper
SE8101536L (sv) * 1981-03-11 1982-09-12 Astra Laekemedel Ab Bensamid-derivat
SE8205135D0 (sv) * 1982-09-09 1982-09-09 Astra Laekemedel Ab Benzamido-derivatives
EP0623601A1 (en) * 1993-04-30 1994-11-09 Shell Internationale Researchmaatschappij B.V. N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides
IL109422A0 (en) * 1993-04-30 1994-07-31 Shell Int Research N-benzyl heterocyclic compounds, process for their preparation and pesticidal compositions containing them
AU2160900A (en) * 1998-12-11 2000-06-26 American Biogenetic Sciences, Inc. Substituted nitrogen heterocyclic compounds and therapeutic uses thereof

Also Published As

Publication number Publication date
ES457872A1 (es) 1978-03-01
CH612668A5 (xx) 1979-08-15
SE7514143L (sv) 1976-06-21
ES443563A1 (es) 1977-08-16
GR59205B (en) 1977-11-26
IE42210B1 (en) 1980-06-18
AU8764675A (en) 1977-06-23
NO754284L (xx) 1976-06-21
NO143625C (no) 1981-03-18
NO143625B (no) 1980-12-08
DE2556457C3 (de) 1981-02-12
DK574075A (da) 1976-06-19
IL48678A (en) 1979-01-31
NL7514620A (nl) 1976-06-22
FI753586A (xx) 1976-06-19
LU74026A1 (xx) 1976-11-11
IE42210L (en) 1976-06-18
AU497616B2 (en) 1978-12-21
AT353782B (de) 1979-12-10
DE2556457B2 (de) 1980-05-29
ATA959075A (de) 1979-05-15
NL168219C (nl) 1982-03-16
GB1508880A (en) 1978-04-26
NL168219B (nl) 1981-10-16
IL48678A0 (en) 1976-02-29
SE412908B (sv) 1980-03-24
DE2556457A1 (de) 1976-06-24
MX3180E (es) 1980-06-11

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