CA1039185A - Hypothyroid serum control - Google Patents
Hypothyroid serum controlInfo
- Publication number
- CA1039185A CA1039185A CA227,609A CA227609A CA1039185A CA 1039185 A CA1039185 A CA 1039185A CA 227609 A CA227609 A CA 227609A CA 1039185 A CA1039185 A CA 1039185A
- Authority
- CA
- Canada
- Prior art keywords
- serum
- hypothyroid
- uptake
- supernatant
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000002966 serum Anatomy 0.000 title claims abstract description 99
- 238000012360 testing method Methods 0.000 claims abstract description 20
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 claims abstract description 9
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 claims abstract description 8
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical compound IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 claims abstract description 8
- 229940034208 thyroxine Drugs 0.000 claims abstract description 7
- 229940035722 triiodothyronine Drugs 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 24
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 14
- 229910052799 carbon Inorganic materials 0.000 claims description 13
- 239000006228 supernatant Substances 0.000 claims description 13
- 239000000203 mixture Substances 0.000 claims description 11
- 206010020850 Hyperthyroidism Diseases 0.000 claims description 7
- 235000015278 beef Nutrition 0.000 claims description 6
- 230000007935 neutral effect Effects 0.000 claims description 6
- 241001465754 Metazoa Species 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 239000013643 reference control Substances 0.000 claims description 4
- 239000002002 slurry Substances 0.000 claims description 4
- 108010000259 Thyroxine-Binding Globulin Proteins 0.000 abstract description 2
- 102000002248 Thyroxine-Binding Globulin Human genes 0.000 abstract description 2
- 102100028709 Thyroxine-binding globulin Human genes 0.000 description 20
- 238000002474 experimental method Methods 0.000 description 7
- 241000736355 Euthyroides Species 0.000 description 5
- 102000004169 proteins and genes Human genes 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 238000009601 thyroid function test Methods 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 229940011871 estrogen Drugs 0.000 description 3
- 239000000262 estrogen Substances 0.000 description 3
- 208000003532 hypothyroidism Diseases 0.000 description 3
- 230000002989 hypothyroidism Effects 0.000 description 3
- 230000002285 radioactive effect Effects 0.000 description 3
- 210000001685 thyroid gland Anatomy 0.000 description 3
- 239000005495 thyroid hormone Substances 0.000 description 3
- 229940036555 thyroid hormone Drugs 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 108010048889 Thyroxine-Binding Proteins Proteins 0.000 description 2
- 102000009488 Thyroxine-Binding Proteins Human genes 0.000 description 2
- 239000003463 adsorbent Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- 230000002860 competitive effect Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000035935 pregnancy Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 241000283707 Capra Species 0.000 description 1
- 102000014914 Carrier Proteins Human genes 0.000 description 1
- 102000006395 Globulins Human genes 0.000 description 1
- 108010044091 Globulins Proteins 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 108091008324 binding proteins Proteins 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229940127234 oral contraceptive Drugs 0.000 description 1
- 239000003539 oral contraceptive agent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940032953 thyroid therapy drug Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/106664—Blood serum or blood plasma standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US473463A US3922145A (en) | 1974-05-28 | 1974-05-28 | Hypothyroid serum control |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1039185A true CA1039185A (en) | 1978-09-26 |
Family
ID=23879629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA227,609A Expired CA1039185A (en) | 1974-05-28 | 1975-05-23 | Hypothyroid serum control |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3922145A (https=) |
| JP (1) | JPS552027B2 (https=) |
| CA (1) | CA1039185A (https=) |
| DE (1) | DE2517219B2 (https=) |
| DK (1) | DK233575A (https=) |
| FR (1) | FR2273282B1 (https=) |
| GB (1) | GB1480199A (https=) |
| IT (1) | IT1038419B (https=) |
| MX (1) | MX3040E (https=) |
| NO (1) | NO751877L (https=) |
| SE (1) | SE7506104L (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230601A (en) * | 1978-05-03 | 1980-10-28 | Eastman Kodak Company | Calibrator composition based upon dialyzed blood serum |
| WO1983000023A1 (en) * | 1981-06-24 | 1983-01-06 | Amf Inc | Process for preparing a zero standard serum |
| US4431741A (en) * | 1981-12-17 | 1984-02-14 | Baxter Travenol Laboratories, Inc. | Hypothyroid control serum |
| JP3363342B2 (ja) * | 1997-05-14 | 2003-01-08 | 本田技研工業株式会社 | 車両用燃料タンクのベント装置 |
| JP7110360B2 (ja) | 2017-10-09 | 2022-08-01 | テルモ ビーシーティー バイオテクノロジーズ，エルエルシー | 凍結乾燥方法 |
| CN113614477B (zh) | 2019-03-14 | 2023-04-28 | 泰尔茂比司特生物技术有限公司 | 冷冻干燥装载托盘组件及系统 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3516794A (en) * | 1964-12-14 | 1970-06-23 | Squibb & Sons Inc | Apparatus and method for determining thyroid function |
| US3743482A (en) * | 1970-12-30 | 1973-07-03 | Nuclear Med Lab | Method and apparatus for determining thyroid function |
| US3775615A (en) * | 1971-07-06 | 1973-11-27 | Nuclear Med Lab | Method of determining thyroid function |
| US3776698A (en) * | 1972-01-24 | 1973-12-04 | Nuclear Med Lab | Test for thyroid hormone |
-
1974
- 1974-05-28 US US473463A patent/US3922145A/en not_active Expired - Lifetime
-
1975
- 1975-04-18 DE DE19752517219 patent/DE2517219B2/de not_active Ceased
- 1975-04-21 MX MX000428U patent/MX3040E/es unknown
- 1975-05-14 GB GB20352/75A patent/GB1480199A/en not_active Expired
- 1975-05-23 FR FR7516183A patent/FR2273282B1/fr not_active Expired
- 1975-05-23 CA CA227,609A patent/CA1039185A/en not_active Expired
- 1975-05-26 IT IT23724/75A patent/IT1038419B/it active
- 1975-05-27 NO NO751877A patent/NO751877L/no unknown
- 1975-05-27 JP JP6341675A patent/JPS552027B2/ja not_active Expired
- 1975-05-27 DK DK233575A patent/DK233575A/da unknown
- 1975-05-28 SE SE7506104A patent/SE7506104L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2517219B2 (de) | 1976-11-04 |
| US3922145A (en) | 1975-11-25 |
| JPS552027B2 (https=) | 1980-01-18 |
| FR2273282B1 (https=) | 1978-02-03 |
| GB1480199A (en) | 1977-07-20 |
| DE2517219A1 (de) | 1975-12-11 |
| MX3040E (es) | 1980-03-04 |
| AU8061975A (en) | 1976-11-04 |
| DK233575A (da) | 1975-11-29 |
| IT1038419B (it) | 1979-11-20 |
| SE7506104L (sv) | 1975-12-01 |
| JPS513290A (https=) | 1976-01-12 |
| FR2273282A1 (https=) | 1975-12-26 |
| NO751877L (https=) | 1975-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Rehfeld et al. | Immunoreactive gastrin components in human serum | |
| McNair et al. | Hypoparathyroidism in diabetes mellitus | |
| Katz | Iron and protein kinetics studied by means of doubly labeled human crystalline transferrin | |
| Venge et al. | Radioimmunoassay of human eosinophil cationic protein | |
| Cartwright et al. | Chemical, clinical, and immunological studies on the products of human plasma fractionation. XXXIX. The anemia of infection. Studies on the iron-binding capacity of serum | |
| Boyce et al. | Total nondialyzable solids (TNDS) in human urine. XIII. Immunological detection of a component peculiar to renal calculous matrix and to urine of calculous patients | |
| IL46708A (en) | Isolation of component materials of aqueous solutions soluble in lipophilic solvents | |
| JPS6122781B2 (https=) | ||
| DE2608667A1 (de) | Diagnostisches feststoffreagens und verfahren zu dessen herstellung | |
| EP0332444B1 (en) | Reagent for diagnosis of cancer | |
| Gamstedt et al. | Corticosteroids and thyroid function: different effects on plasma volume, thyroid hormones and thyroid hormone‐binding proteins after oral and intravenous administration | |
| CA1039185A (en) | Hypothyroid serum control | |
| Neuvonen et al. | Effects of resins and activated charcoal on the absorption of digoxin, carbamazepine and frusemide. | |
| US3941564A (en) | Method for assessing thyroid function | |
| Karp et al. | Thyrotoxicosis from molar thyrotropin | |
| Massaglia et al. | Fractionation of antibodies to testosterone | |
| Goldberg et al. | Enhancement of diphenylhydantoin binding by lipid extraction. | |
| Jochemsen et al. | Pharmacokinetics and bioavailability of intravenous, oral, and rectal nitrazepam in humans | |
| Bourgoin et al. | Characteristics of tryptophan binding in the serum of the newborn rat | |
| JP2672961B2 (ja) | 第▲ｖｉｉｉ▼：ｃ因子欠乏血漿の調製方法 | |
| JPS59148718A (ja) | ユビデカレノン組成物 | |
| Bastomsky et al. | A simple ligand-binding assay for thyroxine-binding globulin on reusable Sephadex columns | |
| Rao et al. | Antisera for radioimmunoassay of 17α-ethynylestradiol and mestranol | |
| US4066410A (en) | Thyroid hormone assay | |
| Laurian et al. | Incidence of immune responses following 102 infusions of autoplex in 18 hemophilic patients with antibody to factor VIII |