CA1037960A - Amidoxime derivatives and process for preparing the same - Google Patents

Amidoxime derivatives and process for preparing the same

Info

Publication number
CA1037960A
CA1037960A CA217,910A CA217910A CA1037960A CA 1037960 A CA1037960 A CA 1037960A CA 217910 A CA217910 A CA 217910A CA 1037960 A CA1037960 A CA 1037960A
Authority
CA
Canada
Prior art keywords
benzofuryloxy
propionamidoxime
process according
acceptable acid
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA217,910A
Other languages
English (en)
French (fr)
Inventor
Fernand Binon
Pierre L. Eymard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Application granted granted Critical
Publication of CA1037960A publication Critical patent/CA1037960A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA217,910A 1974-01-15 1975-01-14 Amidoxime derivatives and process for preparing the same Expired CA1037960A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7401286A FR2257273B1 (US20080138455A1-20080612-C00006.png) 1974-01-15 1974-01-15

Publications (1)

Publication Number Publication Date
CA1037960A true CA1037960A (en) 1978-09-05

Family

ID=9133487

Family Applications (1)

Application Number Title Priority Date Filing Date
CA217,910A Expired CA1037960A (en) 1974-01-15 1975-01-14 Amidoxime derivatives and process for preparing the same

Country Status (23)

Country Link
US (1) US3931240A (US20080138455A1-20080612-C00006.png)
JP (1) JPS541301B2 (US20080138455A1-20080612-C00006.png)
AR (1) AR201414A1 (US20080138455A1-20080612-C00006.png)
AT (1) AT340912B (US20080138455A1-20080612-C00006.png)
BE (1) BE824227A (US20080138455A1-20080612-C00006.png)
CA (1) CA1037960A (US20080138455A1-20080612-C00006.png)
CH (1) CH593245A5 (US20080138455A1-20080612-C00006.png)
DE (1) DE2501122C3 (US20080138455A1-20080612-C00006.png)
DK (1) DK137953B (US20080138455A1-20080612-C00006.png)
ES (1) ES433816A1 (US20080138455A1-20080612-C00006.png)
FI (1) FI63746C (US20080138455A1-20080612-C00006.png)
FR (1) FR2257273B1 (US20080138455A1-20080612-C00006.png)
GB (1) GB1462311A (US20080138455A1-20080612-C00006.png)
HU (1) HU168062B (US20080138455A1-20080612-C00006.png)
IE (1) IE40883B1 (US20080138455A1-20080612-C00006.png)
IT (1) IT1044267B (US20080138455A1-20080612-C00006.png)
NL (1) NL166020C (US20080138455A1-20080612-C00006.png)
NO (1) NO137894C (US20080138455A1-20080612-C00006.png)
OA (1) OA04881A (US20080138455A1-20080612-C00006.png)
SE (1) SE422202B (US20080138455A1-20080612-C00006.png)
SU (1) SU545254A3 (US20080138455A1-20080612-C00006.png)
YU (1) YU36495B (US20080138455A1-20080612-C00006.png)
ZA (1) ZA748105B (US20080138455A1-20080612-C00006.png)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422630A1 (fr) * 1978-04-14 1979-11-09 Synthelabo Derives de propionamidoxime et leur application en therapeutique
FR2506767A1 (fr) 1981-05-26 1982-12-03 Synthelabo Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique
FR2506764A1 (fr) * 1981-05-26 1982-12-03 Synthelabo Derives d'amidoximes, leur preparation et leur application en therapeutique
JPS58131482A (ja) * 1982-01-29 1983-08-05 Matsushita Electric Ind Co Ltd リフト型逆止弁
US4851554A (en) * 1987-04-06 1989-07-25 University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4806663A (en) * 1987-04-06 1989-02-21 The University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4831156A (en) * 1987-09-30 1989-05-16 The University Of Tennessee Research Corp. 3-substituted 2-alkyl indole derivatives
AU5257401A (en) * 2000-04-28 2001-11-12 Asahi Chemical Ind Novel bicyclic compounds

Also Published As

Publication number Publication date
NO750104L (US20080138455A1-20080612-C00006.png) 1975-08-11
DE2501122C3 (de) 1982-03-18
DK645174A (US20080138455A1-20080612-C00006.png) 1975-09-08
ATA26875A (de) 1977-05-15
NL7500399A (nl) 1975-07-17
JPS541301B2 (US20080138455A1-20080612-C00006.png) 1979-01-23
SE7500360L (US20080138455A1-20080612-C00006.png) 1975-07-16
HU168062B (US20080138455A1-20080612-C00006.png) 1976-02-28
AT340912B (de) 1978-01-10
ZA748105B (en) 1976-01-28
AR201414A1 (es) 1975-03-07
NL166020C (nl) 1981-06-15
FI63746B (fi) 1983-04-29
GB1462311A (en) 1977-01-26
ES433816A1 (es) 1976-09-16
SE422202B (sv) 1982-02-22
FR2257273A1 (US20080138455A1-20080612-C00006.png) 1975-08-08
AU7665374A (en) 1976-06-24
CH593245A5 (US20080138455A1-20080612-C00006.png) 1977-11-30
OA04881A (fr) 1980-10-31
NO137894C (no) 1978-05-24
NL166020B (nl) 1981-01-15
DK137953B (da) 1978-06-12
FI353674A (US20080138455A1-20080612-C00006.png) 1975-07-16
JPS50101348A (US20080138455A1-20080612-C00006.png) 1975-08-11
YU36495B (en) 1984-02-29
DE2501122B2 (de) 1981-05-21
NO137894B (no) 1978-02-06
BE824227A (fr) 1975-07-09
FI63746C (fi) 1983-08-10
DK137953C (US20080138455A1-20080612-C00006.png) 1978-12-18
IE40883B1 (en) 1979-09-12
FR2257273B1 (US20080138455A1-20080612-C00006.png) 1978-01-13
YU349874A (en) 1982-02-25
IT1044267B (it) 1980-03-20
US3931240A (en) 1976-01-06
IE40883L (en) 1975-07-15
DE2501122A1 (de) 1975-07-17
SU545254A3 (ru) 1977-01-30

Similar Documents

Publication Publication Date Title
US4569801A (en) Alkylsulfonamidophenylalkylamines
DK175394B1 (da) Lægemiddelpræparat og catecholderivater til brug ved fremstilling deraf
EP0371876A1 (fr) Composés isoxazoles et isoxazolines à activité anticonvulsivante, procédé de préparation et compositions thérapeutiques les contenant
WO2002079143A1 (en) N-phenpropylcyclopentyl-substituted glutaramide derivatives as nep inhibitors for fsad
CA1037960A (en) Amidoxime derivatives and process for preparing the same
EP0114878B1 (en) Phthalazine substituted aminomethyl benzene derivatives, compositions and use
SU728713A3 (ru) Способ получени производных салициланилида
EP0113778A1 (en) ARYL-SUBSTITUTED AMINOMETHYLBENZENE CABBAGE BODIES AS ANTIARRYTHMIC AGENTS.
EP0022118A1 (fr) Nouveaux dérivés de sulfonyl-aniline, leur procédé de préparation et leur application en thérapeutique
CA2351129A1 (en) Novel substituted nitrocatechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them
CH617697A5 (US20080138455A1-20080612-C00006.png)
HU214320B (hu) Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US4596827A (en) Alkylsulfonamidophenylalkylamine compounds used for treating arrhythmia
US5286866A (en) Piperidinyl compounds
US3984470A (en) Amidoxime derivatives and process for preparing the same
DK166878B (da) Fluorallylaminer og pharmakologisk acceptable syreadditionssalte deraf samt pharmaceutisk praeparat indeholdende disse forbindelser
NO152698B (no) Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive 2-hydroxy-5-(1-hydroxy-2-piperazinylethyl)-benzosyrederivater
US4490392A (en) Benzylalcohol derivative and process for preparing
US5118708A (en) Use of 5-phenyl-2-furan esters, amides and ketones as neuroprotective agents
EA014236B1 (ru) Новые пиперазиновые производные диалкилоксиндолов
JPS6214545B2 (US20080138455A1-20080612-C00006.png)
KR102114389B1 (ko) 신규 소듐채널 저해 화합물, 이의 제조방법, 및 이를 포함하는 소듐채널 관련 질환의 예방 또는 치료용 약학적 조성물
DK169328B1 (da) Indolcarboxamidderivater, deres fremstilling samt farmaceutiske præparater med indhold deraf
SU940645A3 (ru) Способ получени производных 1,1 @ -бифенил-2-илалкиламина
RU2194046C2 (ru) Новые нитрометилкетоны, способ их получения и содержащие их композиции